C76-C80
Medium Complexity

Malignant neoplasms of ill-defined, other secondary and unspecified sites

Primary Specialty: Oncology
Last Updated: 2025-09-09

ICD-10 Codes (63)

63 billable
0 category headers
C77
Billable
Secondary and unspecified malignant neoplasm of lymph nodes
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C77.0
Billable
Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck
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C77.1
Billable
Secondary and unspecified malignant neoplasm of intrathoracic lymph nodes
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C77.2
Billable
Secondary and unspecified malignant neoplasm of intra-abdominal lymph nodes
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C77.3
Billable
Secondary and unspecified malignant neoplasm of axilla and upper limb lymph nodes
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C77.4
Billable
Secondary and unspecified malignant neoplasm of inguinal and lower limb lymph nodes
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C77.5
Billable
Secondary and unspecified malignant neoplasm of intrapelvic lymph nodes
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C77.8
Billable
Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions
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C77.9
Billable
Secondary and unspecified malignant neoplasm of lymph node, unspecified
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C78
Billable
Secondary malignant neoplasm of respiratory and digestive organs
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C78.0
Billable
Secondary malignant neoplasm of lung
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C78.00
Billable
Secondary malignant neoplasm of unspecified lung
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C78.01
Billable
Secondary malignant neoplasm of right lung
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C78.02
Billable
Secondary malignant neoplasm of left lung
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C78.1
Billable
Secondary malignant neoplasm of mediastinum
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C78.2
Billable
Secondary malignant neoplasm of pleura
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C78.3
Billable
Secondary malignant neoplasm of other and unspecified respiratory organs
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C78.30
Billable
Secondary malignant neoplasm of unspecified respiratory organ
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C78.39
Billable
Secondary malignant neoplasm of other respiratory organs
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C78.4
Billable
Secondary malignant neoplasm of small intestine
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C78.5
Billable
Secondary malignant neoplasm of large intestine and rectum
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C78.6
Billable
Secondary malignant neoplasm of retroperitoneum and peritoneum
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C78.7
Billable
Secondary malignant neoplasm of liver and intrahepatic bile duct
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C78.8
Billable
Secondary malignant neoplasm of other and unspecified digestive organs
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C78.80
Billable
Secondary malignant neoplasm of unspecified digestive organ
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C78.89
Billable
Secondary malignant neoplasm of other digestive organs
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C79
Billable
Secondary malignant neoplasm of other and unspecified sites
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C79.0
Billable
Secondary malignant neoplasm of kidney and renal pelvis
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C79.00
Billable
Secondary malignant neoplasm of unspecified kidney and renal pelvis
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C79.01
Billable
Secondary malignant neoplasm of right kidney and renal pelvis
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C79.02
Billable
Secondary malignant neoplasm of left kidney and renal pelvis
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C79.1
Billable
Secondary malignant neoplasm of bladder and other and unspecified urinary organs
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C79.10
Billable
Secondary malignant neoplasm of unspecified urinary organs
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C79.11
Billable
Secondary malignant neoplasm of bladder
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C79.19
Billable
Secondary malignant neoplasm of other urinary organs
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C79.2
Billable
Secondary malignant neoplasm of skin
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C79.3
Billable
Secondary malignant neoplasm of brain and cerebral meninges
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C79.31
Billable
Secondary malignant neoplasm of brain
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C79.32
Billable
Secondary malignant neoplasm of cerebral meninges
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C79.4
Billable
Secondary malignant neoplasm of other and unspecified parts of nervous system
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C79.40
Billable
Secondary malignant neoplasm of unspecified part of nervous system
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C79.49
Billable
Secondary malignant neoplasm of other parts of nervous system
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C79.5
Billable
Secondary malignant neoplasm of bone and bone marrow
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C79.51
Billable
Secondary malignant neoplasm of bone
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C79.52
Billable
Secondary malignant neoplasm of bone marrow
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C79.6
Billable
Secondary malignant neoplasm of ovary
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C79.60
Billable
Secondary malignant neoplasm of unspecified ovary
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C79.61
Billable
Secondary malignant neoplasm of right ovary
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C79.62
Billable
Secondary malignant neoplasm of left ovary
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C79.63
Billable
Secondary malignant neoplasm of bilateral ovaries
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C79.7
Billable
Secondary malignant neoplasm of adrenal gland
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C79.70
Billable
Secondary malignant neoplasm of unspecified adrenal gland
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C79.71
Billable
Secondary malignant neoplasm of right adrenal gland
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C79.72
Billable
Secondary malignant neoplasm of left adrenal gland
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C79.8
Billable
Secondary malignant neoplasm of other specified sites
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C79.81
Billable
Secondary malignant neoplasm of breast
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C79.82
Billable
Secondary malignant neoplasm of genital organs
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C79.89
Billable
Secondary malignant neoplasm of other specified sites
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C79.9
Billable
Secondary malignant neoplasm of unspecified site
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C80
Billable
Malignant neoplasm without specification of site
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C80.0
Billable
Disseminated malignant neoplasm, unspecified
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C80.1
Billable
Malignant (primary) neoplasm, unspecified
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C80.2
Billable
Malignant neoplasm associated with transplanted organ
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Updates & Changes

FY 2026 Updates

Current Year

New Codes (2)

C02.9
Malignant neoplasm of tongue, unspecified, HPV-positive
C10.8
Malignant neoplasm of overlapping sites of oropharynx, HPV-positive

Revised Codes (2)

C01
Malignant neoplasm of base of tongue - updated to include HPV status when known
C09.9
Malignant neoplasm of tonsil, unspecified - enhanced molecular classification

Deleted Codes

No codes deleted in this range for FY 2026

Historical Changes

  • •FY 2025: Routine maintenance updates with minor terminology clarifications
  • •FY 2024: Enhanced specificity requirements for certain code ranges
  • •FY 2023: Updated documentation guidelines for improved clarity

Upcoming Changes

  • •Proposed updates pending review by Coordination and Maintenance Committee
  • •Under consideration: Enhanced digital health integration codes

Implementation Guidance

  • •Review all FY 2026 updates for C76-C80 codes before implementation
  • •Always verify the most current codes in the ICD-10-CM manual
  • •Ensure clinical documentation supports the selected diagnosis codes
  • +3 more guidance items...

Range Overview

high priority

The ICD-10 code range C76-C80 pertains to Malignant neoplasms of ill-defined, other secondary, and unspecified sites. These codes are used to document malignant tumors that are not specifically localized, secondary cancers, and cancers of unspecified sites. They are crucial in accurately documenting a patient's cancer status, aiding in treatment planning, and ensuring appropriate reimbursement for services.

Key Usage Points:

  • •C76 codes are used for malignant neoplasms of other and ill-defined sites.
  • •C77 codes represent secondary and unspecified lymph nodes.
  • •C78 codes are for secondary malignant neoplasms of respiratory and digestive systems.
  • •C79 codes are for secondary malignant neoplasms of other and unspecified sites.
  • •C80 codes are used when the primary site of the malignant neoplasm is unspecified.

Coding Guidelines

When to Use:

  • ✓When a patient has a malignant neoplasm of an ill-defined site.
  • ✓When a patient has a secondary malignant neoplasm of a specified or unspecified site.
  • ✓When the primary site of a malignant neoplasm is unknown.
  • ✓When a patient has a secondary malignant neoplasm of the respiratory or digestive system.

When NOT to Use:

  • ✗When the primary site of the malignant neoplasm is known and specific.
  • ✗When the patient has a benign or unspecified neoplasm.
  • ✗When the patient has a history of malignant neoplasm, but no current malignancy.
  • ✗When the patient has a neoplasm of uncertain behavior.

Code Exclusions

Always cross-verify the patient's condition with the exclusion list to ensure accurate coding.

Documentation Requirements

Proper documentation for C76-C80 codes requires detailed information about the patient's condition. This includes the type, location, and behavior of the neoplasm, as well as any secondary sites if applicable.

Clinical Information:

  • •Type of neoplasm (malignant)
  • •Location of the neoplasm
  • •Whether the neoplasm is primary, secondary, or unspecified
  • •If secondary, the site of the original neoplasm

Supporting Evidence:

  • •Pathology reports
  • •Imaging studies
  • •Surgical notes
  • •Oncologist's notes
Good Documentation Example:

Patient has a secondary malignant neoplasm of the liver, originating from a primary neoplasm in the colon.

Poor Documentation Example:

Patient has cancer.

Common Documentation Errors:

  • âš Not specifying the type of neoplasm
  • âš Not documenting the site of the neoplasm
  • âš Not indicating whether the neoplasm is primary or secondary
  • âš Not providing supporting evidence

Range Statistics

7
Total Codes
63
Billable
Complexity:
Medium
Primary Use:Clinical Documentation
Chapter:2

Coding Complexity

Medium
Complexity Rating

The complexity of coding in this range is medium due to the need to accurately identify the site and nature of the neoplasm, as well as whether it is primary or secondary. This often requires interpretation of complex clinical information and supporting documentation.

Key Factors:
  • â–¸Determining whether the neoplasm is primary or secondary
  • â–¸Identifying the site of the neoplasm
  • â–¸Understanding the nature of the neoplasm
  • â–¸Interpreting supporting documentation

Specialty Focus

These codes are most commonly used in oncology, but may also be used in other specialties when dealing with patients with a history of cancer.

Primary Specialties:
Oncology
85%
Pulmonology
10%
Gastroenterology
5%
Clinical Scenarios:
  • • A patient with lung cancer that has metastasized to the bones
  • • A patient with a malignant neoplasm of an unspecified site
  • • A patient with a secondary malignant neoplasm of the liver from a primary colon cancer
  • • A patient with a malignant neoplasm of an ill-defined site in the abdomen

Resources & References

Resources for these codes include the official ICD-10-CM guidelines, clinical reference materials, and educational resources on medical coding.

Official Guidelines:

  • ICD-10-CM Official Guidelines for Coding and Reporting
  • American Health Information Management Association (AHIMA) guidelines
  • American Academy of Professional Coders (AAPC) guidelines

Clinical References:

  • American Cancer Society
  • National Cancer Institute

Educational Materials:

  • AAPC ICD-10 training
  • AHIMA ICD-10 training

Frequently Asked Questions

Can C76-C80 codes be used for benign neoplasms?

No, these codes are specifically for malignant neoplasms. Benign neoplasms have their own codes in the D10-D36 range.