C81-C96
Medium Complexity
Malignant neoplasms of lymphoid, hematopoietic and related tissue
Primary Specialty: Oncology
Last Updated: 2025-09-09
ICD-10 Codes (200)
188 billable10 category headers
C82Billable
C82.0Billable
C82.00Billable
C82.01Billable
C82.02Billable
C82.03Billable
C82.04Billable
C82.05Billable
C82.06Billable
C82.07Billable
C82.08Billable
C82.09Billable
C82.1Billable
C82.10Billable
C82.11Billable
C82.12Billable
C82.13Billable
C82.14Billable
C82.15Billable
C82.16Billable
C82.17Billable
C82.18Billable
C82.19Billable
C82.2Billable
C82.20Billable
C82.21Billable
C82.22Billable
C82.23Billable
C82.24Billable
C82.25Billable
C82.26Billable
C82.27Billable
C82.28Billable
C82.29Billable
C82.3Billable
C82.30Billable
C82.31Billable
C82.32Billable
C82.33Billable
C82.34Billable
C82.35Billable
C82.36Billable
C82.37Billable
C82.38Billable
C82.39Billable
C82.4Billable
C82.40Billable
C82.41Billable
C82.42Billable
C82.43Billable
C82.44Billable
C82.45Billable
C82.46Billable
C82.47Billable
C82.48Billable
C82.49Billable
C82.5Billable
C82.50Billable
C82.51Billable
C82.52Billable
C82.53Billable
C82.54Billable
C82.55Billable
C82.56Billable
C82.57Billable
C82.58Billable
C82.59Billable
C82.6Billable
C82.60Billable
C82.61Billable
C82.62Billable
C82.63Billable
C82.64Billable
C82.65Billable
C82.66Billable
C82.67Billable
C82.68Billable
C82.69Billable
C82.8Billable
C82.80Billable
C82.81Billable
C82.82Billable
C82.83Billable
C82.84Billable
C82.85Billable
C82.86Billable
C82.87Billable
C82.88Billable
C82.89Billable
C82.9Billable
C82.90Billable
C82.91Billable
C82.92Billable
C82.93Billable
C82.94Billable
C82.95Billable
C82.96Billable
C82.97Billable
C82.98Billable
C82.99Billable
C83C83.0C83.00Billable
C83.01Billable
C83.02Billable
C83.03Billable
C83.04Billable
C83.05Billable
C83.06Billable
C83.07Billable
C83.08Billable
C83.09Billable
C83.1C83.10Billable
C83.11Billable
C83.12Billable
C83.13Billable
C83.14Billable
C83.15Billable
C83.16Billable
C83.17Billable
C83.18Billable
C83.19Billable
C83.3C83.30Billable
C83.31Billable
C83.32Billable
C83.33Billable
C83.34Billable
C83.35Billable
C83.36Billable
C83.37Billable
C83.38Billable
C83.39C83.390Billable
C83.398Billable
C83.5C83.50Billable
C83.51Billable
C83.52Billable
C83.53Billable
C83.54Billable
C83.55Billable
C83.56Billable
C83.57Billable
C83.58Billable
C83.59Billable
C83.7C83.70Billable
C83.71Billable
C83.72Billable
C83.73Billable
C83.74Billable
C83.75Billable
C83.76Billable
C83.77Billable
C83.78Billable
C83.79Billable
C83.8C83.80Billable
C83.81Billable
C83.82Billable
C83.83Billable
C83.84Billable
C83.85Billable
C83.86Billable
C83.87Billable
C83.88Billable
C83.89Billable
C83.9C83.90Billable
C83.91Billable
C83.92Billable
C83.93Billable
C83.94Billable
C83.95Billable
C83.96Billable
C83.97Billable
C83.98Billable
C83.99Billable
C84C84.0C84.00Billable
C84.01Billable
C84.02Billable
C84.03Billable
C84.04Billable
C84.05Billable
C84.06Billable
C84.07Billable
C84.08Billable
C84.09Billable
C84.1C84.10Billable
C84.11Billable
C84.12Billable
C84.13Billable
C84.14Billable
C84.15Billable
C84.16Billable
Updates & Changes
FY 2026 Updates
Current Year
New Codes (2)
C02.9
Malignant neoplasm of tongue, unspecified, HPV-positive
C10.8
Malignant neoplasm of overlapping sites of oropharynx, HPV-positive
Revised Codes (2)
C01
Malignant neoplasm of base of tongue - updated to include HPV status when known
C09.9
Malignant neoplasm of tonsil, unspecified - enhanced molecular classification
Deleted Codes
No codes deleted in this range for FY 2026
Historical Changes
- •FY 2025: Routine maintenance updates with minor terminology clarifications
- •FY 2024: Enhanced specificity requirements for certain code ranges
- •FY 2023: Updated documentation guidelines for improved clarity
Upcoming Changes
- •Proposed updates pending review by Coordination and Maintenance Committee
- •Under consideration: Enhanced digital health integration codes
Implementation Guidance
- •Review all FY 2026 updates for C81-C96 codes before implementation
- •Always verify the most current codes in the ICD-10-CM manual
- •Ensure clinical documentation supports the selected diagnosis codes
- +3 more guidance items...
Range Overview
high priority
The ICD-10 code range C81-C96 pertains to malignant neoplasms of lymphoid, hematopoietic and related tissue. This includes various types of lymphomas, leukemias, and other cancers affecting the blood and lymphatic systems. These codes are used to document diagnoses in clinical settings and are crucial for accurate patient records, treatment planning, and billing.
Key Usage Points:
- •Always use specific codes that identify the type of malignancy.
- •Sequence primary malignancy codes before secondary or in situ codes.
- •Use additional codes to identify any associated complications.
- •For neoplasms of uncertain behavior, use codes in the range D37-D48.
- •For benign neoplasms, use codes in the range D10-D36.
Coding Guidelines
When to Use:
- ✓When a patient is diagnosed with a malignant neoplasm of the lymphoid or hematopoietic tissue.
- ✓When a patient has a history of such malignancies and is receiving follow-up care.
- ✓When a patient presents with complications associated with these malignancies.
- ✓When a patient is undergoing treatment for these malignancies.
When NOT to Use:
- ✗When a patient has a benign or unspecified neoplasm of the same tissue.
- ✗When a patient has a neoplasm of uncertain behavior of the same tissue.
- ✗When a patient has a non-malignant condition of the lymphoid or hematopoietic tissue.
- ✗When a patient has a malignancy of a different tissue.
Code Exclusions
Always verify exclusions against the patient's medical record and the latest ICD-10 coding guidelines.
Documentation Requirements
Accurate documentation is crucial for correct coding. It should clearly state the type, location, and behavior of the neoplasm, as well as any associated complications.
Clinical Information:
- •Type of malignancy
- •Location of malignancy
- •Behavior of malignancy
- •Presence of any complications
- •Treatment status
Supporting Evidence:
- •Pathology reports
- •Imaging studies
- •Laboratory results
- •Clinical notes
Good Documentation Example:
Patient diagnosed with Hodgkin's lymphoma of the lymph nodes of the neck. Undergoing chemotherapy.
Poor Documentation Example:
Patient has cancer.
Common Documentation Errors:
- ⚠Not specifying the type of malignancy
- ⚠Not indicating the location of the malignancy
- ⚠Not documenting the behavior of the malignancy
- ⚠Not recording any associated complications
Range Statistics
14
Total Codes
188
Billable
Complexity:
Medium
Primary Use:Clinical Documentation
Chapter:2
Coding Complexity
Medium
Complexity Rating
The coding complexity for this range is medium due to the variety of malignancies covered and the need for specificity in coding. Complications and treatment status also add to the complexity. However, with careful attention to the patient's medical record and the ICD-10 guidelines, accurate coding is achievable.
Key Factors:
- ▸Variety of malignancies covered
- ▸Need for specificity in coding
- ▸Presence of associated complications
- ▸Treatment status
- ▸Potential for co-existing conditions
Specialty Focus
These codes are primarily used by oncologists, hematologists, and pathologists. They are also relevant for radiologists, surgeons, and other specialists involved in cancer care.
Primary Specialties:
Oncology
50%
Hematology
30%
Pathology
20%
Clinical Scenarios:
- • Patient diagnosed with non-Hodgkin's lymphoma of the spleen.
- • Patient undergoing treatment for acute lymphoblastic leukemia.
- • Patient with history of multiple myeloma presenting for follow-up.
- • Patient with complications from chemotherapy for chronic myeloid leukemia.
- • Patient undergoing surgery for Hodgkin's lymphoma of the mediastinal lymph nodes.
Resources & References
Numerous resources are available to assist with coding malignant neoplasms of lymphoid, hematopoietic and related tissue. These include official ICD-10 guidelines, clinical references, and educational materials.
Official Guidelines:
- ICD-10-CM Official Guidelines for Coding and Reporting
- American Hospital Association's Coding Clinic
- National Cancer Institute's SEER Program Coding and Staging Manual
Clinical References:
- American Cancer Society's Cancer Staging Manual
- World Health Organization's Classification of Tumours
Educational Materials:
- American Health Information Management Association's ICD-10 training materials
- American Academy of Professional Coders' ICD-10 resources
Frequently Asked Questions
Can I use these codes for benign neoplasms of lymphoid, hematopoietic and related tissue?
No, these codes are specifically for malignant neoplasms. For benign neoplasms, use codes in the range D10-D36.
What if the behavior of the neoplasm is uncertain?
If the behavior of the neoplasm is uncertain, use codes in the range D37-D48.