E20-E35
Medium Complexity

Disorders of other endocrine glands

Primary Specialty: Endocrinology
Last Updated: 2025-09-09

ICD-10 Codes (113)

113 billable
0 category headers
E21
Billable
Hyperparathyroidism and other disorders of parathyroid gland
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E21.0
Billable
Primary hyperparathyroidism
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E21.1
Billable
Secondary hyperparathyroidism, not elsewhere classified
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E21.2
Billable
Other hyperparathyroidism
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E21.3
Billable
Hyperparathyroidism, unspecified
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E21.4
Billable
Other specified disorders of parathyroid gland
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E21.5
Billable
Disorder of parathyroid gland, unspecified
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E22
Billable
Hyperfunction of pituitary gland
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E22.0
Billable
Acromegaly and pituitary gigantism
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E22.1
Billable
Hyperprolactinemia
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E22.2
Billable
Syndrome of inappropriate secretion of antidiuretic hormone
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E22.8
Billable
Other hyperfunction of pituitary gland
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E22.9
Billable
Hyperfunction of pituitary gland, unspecified
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E23
Billable
Hypofunction and other disorders of the pituitary gland
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E23.0
Billable
Hypopituitarism
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E23.1
Billable
Drug-induced hypopituitarism
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E23.2
Billable
Diabetes insipidus
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E23.3
Billable
Hypothalamic dysfunction, not elsewhere classified
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E23.6
Billable
Other disorders of pituitary gland
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E23.7
Billable
Disorder of pituitary gland, unspecified
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E24
Billable
Cushing's syndrome
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E24.0
Billable
Pituitary-dependent Cushing's disease
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E24.1
Billable
Nelson's syndrome
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E24.2
Billable
Drug-induced Cushing's syndrome
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E24.3
Billable
Ectopic ACTH syndrome
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E24.4
Billable
Alcohol-induced pseudo-Cushing's syndrome
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E24.8
Billable
Other Cushing's syndrome
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E24.9
Billable
Cushing's syndrome, unspecified
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E25
Billable
Adrenogenital disorders
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E25.0
Billable
Congenital adrenogenital disorders associated with enzyme deficiency
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E25.8
Billable
Other adrenogenital disorders
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E25.9
Billable
Adrenogenital disorder, unspecified
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E26
Billable
Hyperaldosteronism
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E26.0
Billable
Primary hyperaldosteronism
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E26.01
Billable
Conn's syndrome
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E26.02
Billable
Glucocorticoid-remediable aldosteronism
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E26.09
Billable
Other primary hyperaldosteronism
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E26.1
Billable
Secondary hyperaldosteronism
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E26.8
Billable
Other hyperaldosteronism
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E26.81
Billable
Bartter's syndrome
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E26.89
Billable
Other hyperaldosteronism
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E26.9
Billable
Hyperaldosteronism, unspecified
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E27
Billable
Other disorders of adrenal gland
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E27.0
Billable
Other adrenocortical overactivity
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E27.1
Billable
Primary adrenocortical insufficiency
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E27.2
Billable
Addisonian crisis
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E27.3
Billable
Drug-induced adrenocortical insufficiency
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E27.4
Billable
Other and unspecified adrenocortical insufficiency
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E27.40
Billable
Unspecified adrenocortical insufficiency
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E27.49
Billable
Other adrenocortical insufficiency
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E27.5
Billable
Adrenomedullary hyperfunction
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E27.8
Billable
Other specified disorders of adrenal gland
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E27.9
Billable
Disorder of adrenal gland, unspecified
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E28
Billable
Ovarian dysfunction
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E28.0
Billable
Estrogen excess
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E28.1
Billable
Androgen excess
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E28.2
Billable
Polycystic ovarian syndrome
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E28.3
Billable
Primary ovarian failure
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E28.31
Billable
Premature menopause
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E28.310
Billable
Symptomatic premature menopause
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E28.319
Billable
Asymptomatic premature menopause
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E28.39
Billable
Other primary ovarian failure
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E28.8
Billable
Other ovarian dysfunction
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E28.9
Billable
Ovarian dysfunction, unspecified
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E29
Billable
Testicular dysfunction
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E29.0
Billable
Testicular hyperfunction
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E29.1
Billable
Testicular hypofunction
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E29.8
Billable
Other testicular dysfunction
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E29.9
Billable
Testicular dysfunction, unspecified
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E30
Billable
Disorders of puberty, not elsewhere classified
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E30.0
Billable
Delayed puberty
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E30.1
Billable
Precocious puberty
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E30.8
Billable
Other disorders of puberty
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E30.9
Billable
Disorder of puberty, unspecified
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E31
Billable
Polyglandular dysfunction
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E31.0
Billable
Autoimmune polyglandular failure
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E31.1
Billable
Polyglandular hyperfunction
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E31.2
Billable
Multiple endocrine neoplasia [MEN] syndromes
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E31.20
Billable
Multiple endocrine neoplasia [MEN] syndrome, unspecified
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E31.21
Billable
Multiple endocrine neoplasia [MEN] type I
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E31.22
Billable
Multiple endocrine neoplasia [MEN] type IIA
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E31.23
Billable
Multiple endocrine neoplasia [MEN] type IIB
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E31.8
Billable
Other polyglandular dysfunction
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E31.9
Billable
Polyglandular dysfunction, unspecified
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E32
Billable
Diseases of thymus
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E32.0
Billable
Persistent hyperplasia of thymus
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E32.1
Billable
Abscess of thymus
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E32.8
Billable
Other diseases of thymus
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E32.9
Billable
Disease of thymus, unspecified
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E34
Billable
Other endocrine disorders
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E34.0
Billable
Carcinoid syndrome
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E34.00
Billable
Carcinoid syndrome, unspecified
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E34.01
Billable
Carcinoid heart syndrome
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E34.09
Billable
Other carcinoid syndrome
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E34.1
Billable
Other hypersecretion of intestinal hormones
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E34.2
Billable
Ectopic hormone secretion, not elsewhere classified
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E34.3
Billable
Short stature due to endocrine disorder
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E34.30
Billable
Short stature due to endocrine disorder, unspecified
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E34.31
Billable
Constitutional short stature
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E34.32
Billable
Genetic causes of short stature
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E34.321
Billable
Primary insulin-like growth factor-1 (IGF-1) deficiency
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E34.322
Billable
Insulin-like growth factor-1 (IGF-1) resistance
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E34.328
Billable
Other genetic causes of short stature
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E34.329
Billable
Unspecified genetic causes of short stature
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E34.39
Billable
Other short stature due to endocrine disorder
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E34.4
Billable
Constitutional tall stature
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E34.5
Billable
Androgen insensitivity syndrome
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E34.50
Billable
Androgen insensitivity syndrome, unspecified
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E34.51
Billable
Complete androgen insensitivity syndrome
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E34.52
Billable
Partial androgen insensitivity syndrome
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E34.8
Billable
Other specified endocrine disorders
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E34.9
Billable
Endocrine disorder, unspecified
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E35
Billable
Disorders of endocrine glands in diseases classified elsewhere
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Updates & Changes

FY 2026 Updates

Current Year

Deleted Codes

No codes deleted in this range for FY 2026

No significant changes for FY 2026

This range maintains stability with current coding practices

Historical Changes

  • •FY 2025: Routine maintenance updates with minor terminology clarifications
  • •FY 2024: Enhanced specificity requirements for certain code ranges
  • •FY 2023: Updated documentation guidelines for improved clarity

Upcoming Changes

  • •Proposed updates pending review by Coordination and Maintenance Committee
  • •Under consideration: Enhanced digital health integration codes

Implementation Guidance

  • •Review all FY 2026 updates for E20-E35 codes before implementation
  • •Always verify the most current codes in the ICD-10-CM manual
  • •Ensure clinical documentation supports the selected diagnosis codes
  • +3 more guidance items...

Range Overview

high priority

The ICD-10 code range E20-E35 pertains to disorders of other endocrine glands. This includes conditions such as hypoparathyroidism, hyperparathyroidism, other disorders of parathyroid gland, multiple endocrine neoplasia [MEN] syndromes, and other specified disorders of endocrine glands. These codes are used to document various endocrine disorders, excluding diabetes mellitus, thyroid disorders, and pituitary gland disorders.

Key Usage Points:

  • •These codes are used for endocrine disorders other than diabetes, thyroid, and pituitary gland disorders.
  • •E20-E35 codes include conditions related to parathyroid, adrenal, and other endocrine glands.
  • •The codes can be used to document both congenital and acquired conditions.
  • •Specificity is crucial when coding within this range, including the type of disorder and the affected gland.
  • •The codes in this range can be used in any healthcare setting, from outpatient clinics to inpatient hospital settings.

Coding Guidelines

When to Use:

  • ✓When a patient is diagnosed with a disorder of the parathyroid gland, such as hyperparathyroidism.
  • ✓When a patient has a disorder of the adrenal gland, such as Addison's disease.
  • ✓When a patient is diagnosed with a multiple endocrine neoplasia syndrome.
  • ✓When a patient has a disorder of the endocrine gland, not otherwise specified.

When NOT to Use:

  • ✗When a patient has a disorder of the thyroid gland; use codes in the E00-E07 range instead.
  • ✗When a patient has diabetes mellitus; use codes in the E08-E13 range instead.
  • ✗When a patient has a disorder of the pituitary gland; use codes in the E22-E23 range instead.
  • ✗When a patient has a disorder of the pancreas; use codes in the E15-E16 range instead.

Code Exclusions

Always verify exclusions with the latest ICD-10-CM official guidelines and the patient's medical record.

Documentation Requirements

Proper documentation for E20-E35 codes should clearly specify the type of endocrine disorder, the affected gland, and any related complications or manifestations. The documentation should be supported by clinical findings, diagnostic tests, and treatment plans.

Clinical Information:

  • •Specific type of endocrine disorder
  • •Affected gland
  • •Presence of any complications or manifestations
  • •Results of any relevant diagnostic tests
  • •Treatment plan

Supporting Evidence:

  • •Medical history
  • •Physical examination findings
  • •Laboratory test results
  • •Imaging studies
Good Documentation Example:

Patient diagnosed with primary hyperparathyroidism. Laboratory tests show elevated parathyroid hormone levels. Plan for surgical removal of parathyroid gland.

Poor Documentation Example:

Patient has endocrine disorder.

Common Documentation Errors:

  • âš Not specifying the type of endocrine disorder
  • âš Not identifying the affected gland
  • âš Not documenting any associated complications or manifestations
  • âš Not providing supporting evidence from clinical findings or diagnostic tests

Range Statistics

15
Total Codes
113
Billable
Complexity:
Medium
Primary Use:Clinical Documentation
Chapter:4

Coding Complexity

Medium
Complexity Rating

The E20-E35 code range has a medium complexity rating due to the need for specificity in identifying the type of endocrine disorder and the affected gland. Additionally, the presence of any complications or manifestations can add to the complexity. Coders must also be aware of exclusions and code sequencing rules.

Key Factors:
  • â–¸Specificity of the endocrine disorder
  • â–¸Identification of the affected gland
  • â–¸Presence of any complications or manifestations
  • â–¸Need for supporting clinical evidence
  • â–¸Exclusions and code sequencing rules

Specialty Focus

The E20-E35 code range is primarily used by endocrinologists, but may also be used by primary care physicians, pediatricians, and surgeons. These codes are used to document a variety of endocrine disorders, excluding diabetes, thyroid, and pituitary gland disorders.

Primary Specialties:
Endocrinology
70%
Primary Care
20%
Pediatrics
5%
Surgery
5%
Clinical Scenarios:
  • • A patient with primary hyperparathyroidism undergoing parathyroidectomy
  • • A child diagnosed with congenital adrenal hyperplasia
  • • A patient with Addison's disease receiving hormone replacement therapy
  • • A patient diagnosed with multiple endocrine neoplasia syndrome undergoing genetic testing

Resources & References

There are several resources available for coding endocrine disorders, including the official ICD-10-CM guidelines, clinical reference books, and educational materials from professional coding organizations.

Official Guidelines:

  • ICD-10-CM Official Guidelines for Coding and Reporting
  • World Health Organization's ICD-10 Classification of Diseases
  • National Center for Health Statistics' ICD-10-CM Index and Tabular List

Clinical References:

  • Endocrine Society's Clinical Practice Guidelines
  • American Association of Clinical Endocrinologists' Clinical Practice Guidelines

Educational Materials:

  • American Academy of Professional Coders' ICD-10-CM Training
  • American Health Information Management Association's ICD-10-CM Coding Resources

Frequently Asked Questions

Can E20-E35 codes be used for diabetes or thyroid disorders?

No, diabetes and thyroid disorders have their own specific code ranges (E08-E13 for diabetes and E00-E07 for thyroid disorders).

What documentation is needed to code within the E20-E35 range?

Documentation should specify the type of endocrine disorder, the affected gland, and any related complications or manifestations. It should be supported by clinical findings, diagnostic tests, and treatment plans.