F10-F19
Medium Complexity

Mental and behavioral disorders due to psychoactive substance use

Primary Specialty: Psychiatry
Last Updated: 2025-09-09

ICD-10 Codes (200)

200 billable
0 category headers
F11
Billable
Opioid related disorders
View
F11.1
Billable
Opioid abuse
View
F11.10
Billable
Opioid abuse, uncomplicated
View
F11.11
Billable
Opioid abuse, in remission
View
F11.12
Billable
Opioid abuse with intoxication
View
F11.120
Billable
Opioid abuse with intoxication, uncomplicated
View
F11.121
Billable
Opioid abuse with intoxication delirium
View
F11.122
Billable
Opioid abuse with intoxication with perceptual disturbance
View
F11.129
Billable
Opioid abuse with intoxication, unspecified
View
F11.13
Billable
Opioid abuse with withdrawal
View
F11.14
Billable
Opioid abuse with opioid-induced mood disorder
View
F11.15
Billable
Opioid abuse with opioid-induced psychotic disorder
View
F11.150
Billable
Opioid abuse with opioid-induced psychotic disorder with delusions
View
F11.151
Billable
Opioid abuse with opioid-induced psychotic disorder with hallucinations
View
F11.159
Billable
Opioid abuse with opioid-induced psychotic disorder, unspecified
View
F11.18
Billable
Opioid abuse with other opioid-induced disorder
View
F11.181
Billable
Opioid abuse with opioid-induced sexual dysfunction
View
F11.182
Billable
Opioid abuse with opioid-induced sleep disorder
View
F11.188
Billable
Opioid abuse with other opioid-induced disorder
View
F11.19
Billable
Opioid abuse with unspecified opioid-induced disorder
View
F11.2
Billable
Opioid dependence
View
F11.20
Billable
Opioid dependence, uncomplicated
View
F11.21
Billable
Opioid dependence, in remission
View
F11.22
Billable
Opioid dependence with intoxication
View
F11.220
Billable
Opioid dependence with intoxication, uncomplicated
View
F11.221
Billable
Opioid dependence with intoxication delirium
View
F11.222
Billable
Opioid dependence with intoxication with perceptual disturbance
View
F11.229
Billable
Opioid dependence with intoxication, unspecified
View
F11.23
Billable
Opioid dependence with withdrawal
View
F11.24
Billable
Opioid dependence with opioid-induced mood disorder
View
F11.25
Billable
Opioid dependence with opioid-induced psychotic disorder
View
F11.250
Billable
Opioid dependence with opioid-induced psychotic disorder with delusions
View
F11.251
Billable
Opioid dependence with opioid-induced psychotic disorder with hallucinations
View
F11.259
Billable
Opioid dependence with opioid-induced psychotic disorder, unspecified
View
F11.28
Billable
Opioid dependence with other opioid-induced disorder
View
F11.281
Billable
Opioid dependence with opioid-induced sexual dysfunction
View
F11.282
Billable
Opioid dependence with opioid-induced sleep disorder
View
F11.288
Billable
Opioid dependence with other opioid-induced disorder
View
F11.29
Billable
Opioid dependence with unspecified opioid-induced disorder
View
F11.9
Billable
Opioid use, unspecified
View
F11.90
Billable
Opioid use, unspecified, uncomplicated
View
F11.91
Billable
Opioid use, unspecified, in remission
View
F11.92
Billable
Opioid use, unspecified with intoxication
View
F11.920
Billable
Opioid use, unspecified with intoxication, uncomplicated
View
F11.921
Billable
Opioid use, unspecified with intoxication delirium
View
F11.922
Billable
Opioid use, unspecified with intoxication with perceptual disturbance
View
F11.929
Billable
Opioid use, unspecified with intoxication, unspecified
View
F11.93
Billable
Opioid use, unspecified with withdrawal
View
F11.94
Billable
Opioid use, unspecified with opioid-induced mood disorder
View
F11.95
Billable
Opioid use, unspecified with opioid-induced psychotic disorder
View
F11.950
Billable
Opioid use, unspecified with opioid-induced psychotic disorder with delusions
View
F11.951
Billable
Opioid use, unspecified with opioid-induced psychotic disorder with hallucinations
View
F11.959
Billable
Opioid use, unspecified with opioid-induced psychotic disorder, unspecified
View
F11.98
Billable
Opioid use, unspecified with other specified opioid-induced disorder
View
F11.981
Billable
Opioid use, unspecified with opioid-induced sexual dysfunction
View
F11.982
Billable
Opioid use, unspecified with opioid-induced sleep disorder
View
F11.988
Billable
Opioid use, unspecified with other opioid-induced disorder
View
F11.99
Billable
Opioid use, unspecified with unspecified opioid-induced disorder
View
F12
Billable
Cannabis related disorders
View
F12.1
Billable
Cannabis abuse
View
F12.10
Billable
Cannabis abuse, uncomplicated
View
F12.11
Billable
Cannabis abuse, in remission
View
F12.12
Billable
Cannabis abuse with intoxication
View
F12.120
Billable
Cannabis abuse with intoxication, uncomplicated
View
F12.121
Billable
Cannabis abuse with intoxication delirium
View
F12.122
Billable
Cannabis abuse with intoxication with perceptual disturbance
View
F12.129
Billable
Cannabis abuse with intoxication, unspecified
View
F12.13
Billable
Cannabis abuse with withdrawal
View
F12.15
Billable
Cannabis abuse with psychotic disorder
View
F12.150
Billable
Cannabis abuse with psychotic disorder with delusions
View
F12.151
Billable
Cannabis abuse with psychotic disorder with hallucinations
View
F12.159
Billable
Cannabis abuse with psychotic disorder, unspecified
View
F12.18
Billable
Cannabis abuse with other cannabis-induced disorder
View
F12.180
Billable
Cannabis abuse with cannabis-induced anxiety disorder
View
F12.188
Billable
Cannabis abuse with other cannabis-induced disorder
View
F12.19
Billable
Cannabis abuse with unspecified cannabis-induced disorder
View
F12.2
Billable
Cannabis dependence
View
F12.20
Billable
Cannabis dependence, uncomplicated
View
F12.21
Billable
Cannabis dependence, in remission
View
F12.22
Billable
Cannabis dependence with intoxication
View
F12.220
Billable
Cannabis dependence with intoxication, uncomplicated
View
F12.221
Billable
Cannabis dependence with intoxication delirium
View
F12.222
Billable
Cannabis dependence with intoxication with perceptual disturbance
View
F12.229
Billable
Cannabis dependence with intoxication, unspecified
View
F12.23
Billable
Cannabis dependence with withdrawal
View
F12.25
Billable
Cannabis dependence with psychotic disorder
View
F12.250
Billable
Cannabis dependence with psychotic disorder with delusions
View
F12.251
Billable
Cannabis dependence with psychotic disorder with hallucinations
View
F12.259
Billable
Cannabis dependence with psychotic disorder, unspecified
View
F12.28
Billable
Cannabis dependence with other cannabis-induced disorder
View
F12.280
Billable
Cannabis dependence with cannabis-induced anxiety disorder
View
F12.288
Billable
Cannabis dependence with other cannabis-induced disorder
View
F12.29
Billable
Cannabis dependence with unspecified cannabis-induced disorder
View
F12.9
Billable
Cannabis use, unspecified
View
F12.90
Billable
Cannabis use, unspecified, uncomplicated
View
F12.91
Billable
Cannabis use, unspecified, in remission
View
F12.92
Billable
Cannabis use, unspecified with intoxication
View
F12.920
Billable
Cannabis use, unspecified with intoxication, uncomplicated
View
F12.921
Billable
Cannabis use, unspecified with intoxication delirium
View
F12.922
Billable
Cannabis use, unspecified with intoxication with perceptual disturbance
View
F12.929
Billable
Cannabis use, unspecified with intoxication, unspecified
View
F12.93
Billable
Cannabis use, unspecified with withdrawal
View
F12.95
Billable
Cannabis use, unspecified with psychotic disorder
View
F12.950
Billable
Cannabis use, unspecified with psychotic disorder with delusions
View
F12.951
Billable
Cannabis use, unspecified with psychotic disorder with hallucinations
View
F12.959
Billable
Cannabis use, unspecified with psychotic disorder, unspecified
View
F12.98
Billable
Cannabis use, unspecified with other cannabis-induced disorder
View
F12.980
Billable
Cannabis use, unspecified with anxiety disorder
View
F12.988
Billable
Cannabis use, unspecified with other cannabis-induced disorder
View
F12.99
Billable
Cannabis use, unspecified with unspecified cannabis-induced disorder
View
F13
Billable
Sedative, hypnotic, or anxiolytic related disorders
View
F13.1
Billable
Sedative, hypnotic or anxiolytic-related abuse
View
F13.10
Billable
Sedative, hypnotic or anxiolytic abuse, uncomplicated
View
F13.11
Billable
Sedative, hypnotic or anxiolytic abuse, in remission
View
F13.12
Billable
Sedative, hypnotic or anxiolytic abuse with intoxication
View
F13.120
Billable
Sedative, hypnotic or anxiolytic abuse with intoxication, uncomplicated
View
F13.121
Billable
Sedative, hypnotic or anxiolytic abuse with intoxication delirium
View
F13.129
Billable
Sedative, hypnotic or anxiolytic abuse with intoxication, unspecified
View
F13.13
Billable
Sedative, hypnotic or anxiolytic abuse with withdrawal
View
F13.130
Billable
Sedative, hypnotic or anxiolytic abuse with withdrawal, uncomplicated
View
F13.131
Billable
Sedative, hypnotic or anxiolytic abuse with withdrawal delirium
View
F13.132
Billable
Sedative, hypnotic or anxiolytic abuse with withdrawal with perceptual disturbance
View
F13.139
Billable
Sedative, hypnotic or anxiolytic abuse with withdrawal, unspecified
View
F13.14
Billable
Sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced mood disorder
View
F13.15
Billable
Sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced psychotic disorder
View
F13.150
Billable
Sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced psychotic disorder with delusions
View
F13.151
Billable
Sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced psychotic disorder with hallucinations
View
F13.159
Billable
Sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced psychotic disorder, unspecified
View
F13.18
Billable
Sedative, hypnotic or anxiolytic abuse with other sedative, hypnotic or anxiolytic-induced disorders
View
F13.180
Billable
Sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced anxiety disorder
View
F13.181
Billable
Sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced sexual dysfunction
View
F13.182
Billable
Sedative, hypnotic or anxiolytic abuse with sedative, hypnotic or anxiolytic-induced sleep disorder
View
F13.188
Billable
Sedative, hypnotic or anxiolytic abuse with other sedative, hypnotic or anxiolytic-induced disorder
View
F13.19
Billable
Sedative, hypnotic or anxiolytic abuse with unspecified sedative, hypnotic or anxiolytic-induced disorder
View
F13.2
Billable
Sedative, hypnotic or anxiolytic-related dependence
View
F13.20
Billable
Sedative, hypnotic or anxiolytic dependence, uncomplicated
View
F13.21
Billable
Sedative, hypnotic or anxiolytic dependence, in remission
View
F13.22
Billable
Sedative, hypnotic or anxiolytic dependence with intoxication
View
F13.220
Billable
Sedative, hypnotic or anxiolytic dependence with intoxication, uncomplicated
View
F13.221
Billable
Sedative, hypnotic or anxiolytic dependence with intoxication delirium
View
F13.229
Billable
Sedative, hypnotic or anxiolytic dependence with intoxication, unspecified
View
F13.23
Billable
Sedative, hypnotic or anxiolytic dependence with withdrawal
View
F13.230
Billable
Sedative, hypnotic or anxiolytic dependence with withdrawal, uncomplicated
View
F13.231
Billable
Sedative, hypnotic or anxiolytic dependence with withdrawal delirium
View
F13.232
Billable
Sedative, hypnotic or anxiolytic dependence with withdrawal with perceptual disturbance
View
F13.239
Billable
Sedative, hypnotic or anxiolytic dependence with withdrawal, unspecified
View
F13.24
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced mood disorder
View
F13.25
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced psychotic disorder
View
F13.250
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced psychotic disorder with delusions
View
F13.251
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced psychotic disorder with hallucinations
View
F13.259
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced psychotic disorder, unspecified
View
F13.26
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced persisting amnestic disorder
View
F13.27
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced persisting dementia
View
F13.28
Billable
Sedative, hypnotic or anxiolytic dependence with other sedative, hypnotic or anxiolytic-induced disorders
View
F13.280
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced anxiety disorder
View
F13.281
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced sexual dysfunction
View
F13.282
Billable
Sedative, hypnotic or anxiolytic dependence with sedative, hypnotic or anxiolytic-induced sleep disorder
View
F13.288
Billable
Sedative, hypnotic or anxiolytic dependence with other sedative, hypnotic or anxiolytic-induced disorder
View
F13.29
Billable
Sedative, hypnotic or anxiolytic dependence with unspecified sedative, hypnotic or anxiolytic-induced disorder
View
F13.9
Billable
Sedative, hypnotic or anxiolytic-related use, unspecified
View
F13.90
Billable
Sedative, hypnotic, or anxiolytic use, unspecified, uncomplicated
View
F13.91
Billable
Sedative, hypnotic or anxiolytic use, unspecified, in remission
View
F13.92
Billable
Sedative, hypnotic or anxiolytic use, unspecified with intoxication
View
F13.920
Billable
Sedative, hypnotic or anxiolytic use, unspecified with intoxication, uncomplicated
View
F13.921
Billable
Sedative, hypnotic or anxiolytic use, unspecified with intoxication delirium
View
F13.929
Billable
Sedative, hypnotic or anxiolytic use, unspecified with intoxication, unspecified
View
F13.93
Billable
Sedative, hypnotic or anxiolytic use, unspecified with withdrawal
View
F13.930
Billable
Sedative, hypnotic or anxiolytic use, unspecified with withdrawal, uncomplicated
View
F13.931
Billable
Sedative, hypnotic or anxiolytic use, unspecified with withdrawal delirium
View
F13.932
Billable
Sedative, hypnotic or anxiolytic use, unspecified with withdrawal with perceptual disturbances
View
F13.939
Billable
Sedative, hypnotic or anxiolytic use, unspecified with withdrawal, unspecified
View
F13.94
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced mood disorder
View
F13.95
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced psychotic disorder
View
F13.950
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced psychotic disorder with delusions
View
F13.951
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced psychotic disorder with hallucinations
View
F13.959
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced psychotic disorder, unspecified
View
F13.96
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced persisting amnestic disorder
View
F13.97
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced persisting dementia
View
F13.98
Billable
Sedative, hypnotic or anxiolytic use, unspecified with other sedative, hypnotic or anxiolytic-induced disorders
View
F13.980
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced anxiety disorder
View
F13.981
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced sexual dysfunction
View
F13.982
Billable
Sedative, hypnotic or anxiolytic use, unspecified with sedative, hypnotic or anxiolytic-induced sleep disorder
View
F13.988
Billable
Sedative, hypnotic or anxiolytic use, unspecified with other sedative, hypnotic or anxiolytic-induced disorder
View
F13.99
Billable
Sedative, hypnotic or anxiolytic use, unspecified with unspecified sedative, hypnotic or anxiolytic-induced disorder
View
F14
Billable
Cocaine related disorders
View
F14.1
Billable
Cocaine abuse
View
F14.10
Billable
Cocaine abuse, uncomplicated
View
F14.11
Billable
Cocaine abuse, in remission
View
F14.12
Billable
Cocaine abuse with intoxication
View
F14.120
Billable
Cocaine abuse with intoxication, uncomplicated
View
F14.121
Billable
Cocaine abuse with intoxication with delirium
View
F14.122
Billable
Cocaine abuse with intoxication with perceptual disturbance
View
F14.129
Billable
Cocaine abuse with intoxication, unspecified
View
F14.13
Billable
Cocaine abuse, unspecified with withdrawal
View
F14.14
Billable
Cocaine abuse with cocaine-induced mood disorder
View
F14.15
Billable
Cocaine abuse with cocaine-induced psychotic disorder
View
F14.150
Billable
Cocaine abuse with cocaine-induced psychotic disorder with delusions
View
F14.151
Billable
Cocaine abuse with cocaine-induced psychotic disorder with hallucinations
View
F14.159
Billable
Cocaine abuse with cocaine-induced psychotic disorder, unspecified
View
F14.18
Billable
Cocaine abuse with other cocaine-induced disorder
View

Updates & Changes

FY 2026 Updates

Current Year

New Codes (2)

F10.288
Alcohol use disorder with other alcohol-induced disorder, severe
F11.288
Opioid use disorder with other opioid-induced disorder, severe

Revised Codes (2)

F11.10
Opioid abuse, uncomplicated - updated to align with DSM-5-TR criteria
F12.10
Cannabis abuse, uncomplicated - updated terminology and criteria

Deleted Codes

No codes deleted in this range for FY 2026

Historical Changes

  • •FY 2025: Updated substance use disorder severity classifications
  • •FY 2024: Enhanced coding for medication-assisted treatment
  • •FY 2023: Added codes for cannabis hyperemesis syndrome

Upcoming Changes

  • •Proposed codes for synthetic drug use disorders
  • •Under review: Enhanced coding for dual diagnosis conditions

Implementation Guidance

  • •Review all FY 2026 updates for F10-F19 codes before implementation
  • •Always verify the most current codes in the ICD-10-CM manual
  • •Ensure clinical documentation supports the selected diagnosis codes
  • +3 more guidance items...

Range Overview

high priority

The F10-F19 range in ICD-10 pertains to mental and behavioral disorders due to psychoactive substance use. This includes conditions resulting from the abuse, dependence, withdrawal, or induced disorders from substances like alcohol, opioids, cannabinoids, sedatives, cocaine, and other stimulants. The codes also account for remission states and unspecified psychoactive substance use disorders.

Key Usage Points:

  • •F10-F19 codes should specify the substance involved, the nature of the disorder (dependence, abuse, etc.), and the current state (acute intoxication, withdrawal, etc.).
  • •The fifth character in these codes typically indicates the clinical state of the disorder.
  • •F10-F19 codes can be used in conjunction with Z codes (Z50-Z59) to indicate ongoing treatment or counseling for substance use.
  • •In cases of polysubstance abuse, multiple codes from this range may be necessary.
  • •F19 codes are used when the substance causing the disorder is not specified.

Coding Guidelines

When to Use:

  • ✓When a patient presents with symptoms of withdrawal from a specific substance.
  • ✓When a patient is diagnosed with substance-induced mental disorders.
  • ✓When a patient is in remission from substance abuse and is receiving ongoing treatment.
  • ✓When a patient's condition is directly caused by the misuse of a psychoactive substance.
  • ✓When a patient has a history of substance abuse, even if currently in remission.

When NOT to Use:

  • ✗When a patient's substance use is recreational and does not meet criteria for abuse or dependence.
  • ✗When a patient's mental disorder is not directly caused by substance use.
  • ✗When a patient's substance use is under the supervision of a physician (e.g., prescription medications).
  • ✗When a patient's symptoms are due to intoxication but do not meet the criteria for a substance use disorder.
  • ✗When a patient has a history of substance use but has never been diagnosed with a substance use disorder.

Code Exclusions

Always verify exclusions with the latest ICD-10-CM official guidelines and the patient's medical record.

Documentation Requirements

Documentation for F10-F19 codes should clearly state the substance involved, the nature of the disorder, and the current clinical state. It should also include any relevant history of substance use and any associated mental or physical health conditions.

Clinical Information:

  • •Specific substance causing the disorder
  • •Nature of the disorder (abuse, dependence, withdrawal, etc.)
  • •Current clinical state (acute intoxication, in remission, etc.)
  • •History of substance use
  • •Associated mental or physical health conditions

Supporting Evidence:

  • •Clinical notes from mental health professionals
  • •Results from substance use screening tools
  • •Laboratory test results confirming substance use
  • •Patient self-reports or reports from family members
Good Documentation Example:

Patient presents with severe withdrawal symptoms from chronic alcohol use. Diagnosed with alcohol dependence, currently in withdrawal (F10.23).

Common Documentation Errors:

  • âš Not specifying the substance involved
  • âš Not indicating the nature of the disorder
  • âš Not documenting the current clinical state
  • âš Not including associated mental or physical health conditions

Range Statistics

10
Total Codes
200
Billable
Complexity:
Medium
Primary Use:Clinical Documentation
Chapter:5

Coding Complexity

Medium
Complexity Rating

Coding for F10-F19 can be complex due to the need to accurately identify the substance involved, the nature of the disorder, and the current clinical state. Additionally, associated mental and physical health conditions can complicate the coding process. In cases of polysubstance abuse, multiple codes may need to be used, further increasing complexity.

Key Factors:
  • â–¸Determining the specific substance involved
  • â–¸Identifying the nature of the disorder
  • â–¸Assessing the current clinical state
  • â–¸Considering associated mental and physical health conditions
  • â–¸Navigating multiple codes in cases of polysubstance abuse

Specialty Focus

F10-F19 codes are most commonly used in psychiatry, addiction medicine, and emergency medicine. They can also be relevant in primary care, especially when managing patients with chronic substance use disorders.

Primary Specialties:
Psychiatry
40%
Addiction Medicine
30%
Emergency Medicine
20%
Primary Care
10%
Clinical Scenarios:
  • • A patient presenting to the ER with symptoms of opioid withdrawal.
  • • A patient in a psychiatric clinic diagnosed with cannabis-induced psychosis.
  • • A patient in an addiction treatment center being treated for alcohol dependence.
  • • A patient in primary care being screened for substance use disorders.

Resources & References

Resources for F10-F19 coding include the ICD-10-CM official guidelines, the DSM-5 criteria for substance use disorders, and various clinical and educational resources on substance use disorders.

Official Guidelines:

  • ICD-10-CM Official Guidelines for Coding and Reporting
  • DSM-5 Criteria for Substance Use Disorders
  • World Health Organization's ICD-10 Classification of Mental and Behavioural Disorders

Clinical References:

  • American Society of Addiction Medicine
  • National Institute on Drug Abuse
  • Substance Abuse and Mental Health Services Administration

Educational Materials:

  • American Health Information Management Association (AHIMA)
  • American Academy of Professional Coders (AAPC)
  • Centers for Disease Control and Prevention (CDC) ICD-10 Training

Frequently Asked Questions

How do I code for a patient with polysubstance abuse?

In cases of polysubstance abuse, you may need to use multiple codes from the F10-F19 range to accurately represent each substance involved.

What if the substance causing the disorder is not specified?

If the substance is not specified, you can use codes from the F19 range.