R40-R69
Medium Complexity

Symptoms and signs involving cognition, perception, emotional state and behavior

Primary Specialty: General Practice
Last Updated: 2025-09-10

ICD-10 Codes (179)

170 billable
0 category headers
R41
Other symptoms and signs involving cognitive functions and awareness
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R41.0
Billable
Disorientation, unspecified
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R41.1
Billable
Anterograde amnesia
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R41.2
Billable
Retrograde amnesia
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R41.3
Billable
Other amnesia
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R41.4
Billable
Neurologic neglect syndrome
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R41.8
Billable
Other symptoms and signs involving cognitive functions and awareness
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R41.81
Billable
Age-related cognitive decline
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R41.82
Billable
Altered mental status, unspecified
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R41.83
Billable
Borderline intellectual functioning
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R41.84
Billable
Other specified cognitive deficit
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R41.840
Billable
Attention and concentration deficit
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R41.841
Billable
Cognitive communication deficit
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R41.842
Billable
Visuospatial deficit
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R41.843
Billable
Psychomotor deficit
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R41.844
Billable
Frontal lobe and executive function deficit
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R41.85
Billable
Anosognosia
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R41.89
Billable
Other symptoms and signs involving cognitive functions and awareness
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R41.9
Billable
Unspecified symptoms and signs involving cognitive functions and awareness
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R42
Billable
Dizziness and giddiness
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R43
Disturbances of smell and taste
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R43.0
Billable
Anosmia
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R43.1
Billable
Parosmia
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R43.2
Billable
Parageusia
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R43.8
Billable
Other disturbances of smell and taste
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R43.9
Billable
Unspecified disturbances of smell and taste
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R44
Billable
Other symptoms and signs involving general sensations and perceptions
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R44.0
Billable
Auditory hallucinations
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R44.1
Billable
Visual hallucinations
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R44.2
Billable
Other hallucinations
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R44.3
Billable
Hallucinations, unspecified
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R44.8
Billable
Other symptoms and signs involving general sensations and perceptions
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R44.9
Billable
Unspecified symptoms and signs involving general sensations and perceptions
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R45
Billable
Symptoms and signs involving emotional state
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R45.0
Billable
Nervousness
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R45.1
Billable
Restlessness and agitation
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R45.2
Billable
Unhappiness
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R45.3
Billable
Demoralization and apathy
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R45.4
Billable
Irritability and anger
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R45.5
Billable
Hostility
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R45.6
Billable
Violent behavior
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R45.7
Billable
State of emotional shock and stress, unspecified
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R45.8
Billable
Other symptoms and signs involving emotional state
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R45.81
Billable
Low self-esteem
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R45.82
Billable
Worries
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R45.83
Billable
Excessive crying of child, adolescent or adult
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R45.84
Billable
Anhedonia
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R45.85
Billable
Homicidal and suicidal ideations
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R45.850
Billable
Homicidal ideations
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R45.851
Billable
Suicidal ideations
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R45.86
Billable
Emotional lability
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R45.87
Billable
Impulsiveness
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R45.88
Billable
Nonsuicidal self-harm
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R45.89
Billable
Other symptoms and signs involving emotional state
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R46
Symptoms and signs involving appearance and behavior
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R46.0
Billable
Very low level of personal hygiene
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R46.1
Billable
Bizarre personal appearance
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R46.2
Billable
Strange and inexplicable behavior
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R46.3
Billable
Overactivity
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R46.4
Billable
Slowness and poor responsiveness
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R46.5
Billable
Suspiciousness and marked evasiveness
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R46.6
Billable
Undue concern and preoccupation with stressful events
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R46.7
Billable
Verbosity and circumstantial detail obscuring reason for contact
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R46.8
Billable
Other symptoms and signs involving appearance and behavior
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R46.81
Billable
Obsessive-compulsive behavior
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R46.89
Billable
Other symptoms and signs involving appearance and behavior
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R47
Speech disturbances, not elsewhere classified
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R47.0
Billable
Dysphasia and aphasia
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R47.01
Billable
Aphasia
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R47.02
Billable
Dysphasia
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R47.1
Billable
Dysarthria and anarthria
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R47.8
Billable
Other speech disturbances
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R47.81
Billable
Slurred speech
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R47.82
Billable
Fluency disorder in conditions classified elsewhere
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R47.89
Billable
Other speech disturbances
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R47.9
Billable
Unspecified speech disturbances
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R48
Billable
Dyslexia and other symbolic dysfunctions, not elsewhere classified
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R48.0
Billable
Dyslexia and alexia
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R48.1
Billable
Agnosia
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R48.2
Billable
Apraxia
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R48.3
Billable
Visual agnosia
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R48.8
Billable
Other symbolic dysfunctions
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R48.9
Billable
Unspecified symbolic dysfunctions
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R49
Billable
Voice and resonance disorders
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R49.0
Billable
Dysphonia
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R49.1
Billable
Aphonia
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R49.2
Billable
Hypernasality and hyponasality
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R49.21
Billable
Hypernasality
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R49.22
Billable
Hyponasality
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R49.8
Billable
Other voice and resonance disorders
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R49.9
Billable
Unspecified voice and resonance disorder
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R50
Billable
Fever of other and unknown origin
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R50.2
Billable
Drug induced fever
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R50.8
Billable
Other specified fever
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R50.81
Billable
Fever presenting with conditions classified elsewhere
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R50.82
Billable
Postprocedural fever
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R50.83
Billable
Postvaccination fever
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R50.84
Billable
Febrile nonhemolytic transfusion reaction
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R50.9
Billable
Fever, unspecified
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R51
Headache
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R51.0
Billable
Headache with orthostatic component, not elsewhere classified
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R51.9
Billable
Headache, unspecified
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R52
Billable
Pain, unspecified
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R53
Billable
Malaise and fatigue
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R53.0
Billable
Neoplastic (malignant) related fatigue
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R53.1
Billable
Weakness
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R53.2
Billable
Functional quadriplegia
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R53.8
Billable
Other malaise and fatigue
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R53.81
Billable
Other malaise
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R53.82
Billable
Chronic fatigue, unspecified
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R53.83
Billable
Other fatigue
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R54
Billable
Age-related physical debility
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R55
Billable
Syncope and collapse
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R56
Billable
Convulsions, not elsewhere classified
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R56.0
Billable
Febrile convulsions
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R56.00
Billable
Simple febrile convulsions
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R56.01
Billable
Complex febrile convulsions
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R56.1
Billable
Post traumatic seizures
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R56.9
Billable
Unspecified convulsions
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R57
Billable
Shock, not elsewhere classified
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R57.0
Billable
Cardiogenic shock
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R57.1
Billable
Hypovolemic shock
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R57.8
Billable
Other shock
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R57.9
Billable
Shock, unspecified
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R58
Billable
Hemorrhage, not elsewhere classified
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R59
Enlarged lymph nodes
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R59.0
Billable
Localized enlarged lymph nodes
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R59.1
Billable
Generalized enlarged lymph nodes
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R59.9
Billable
Enlarged lymph nodes, unspecified
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R60
Billable
Edema, not elsewhere classified
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R60.0
Billable
Localized edema
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R60.1
Billable
Generalized edema
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R60.9
Billable
Edema, unspecified
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R61
Billable
Generalized hyperhidrosis
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R62
Lack of expected normal physiological development in childhood and adults
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R62.0
Billable
Delayed milestone in childhood
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R62.5
Billable
Other and unspecified lack of expected normal physiological development in childhood
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R62.50
Billable
Unspecified lack of expected normal physiological development in childhood
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R62.51
Billable
Failure to thrive (child)
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R62.52
Billable
Short stature (child)
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R62.59
Billable
Other lack of expected normal physiological development in childhood
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R62.7
Billable
Adult failure to thrive
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R63
Symptoms and signs concerning food and fluid intake
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R63.0
Billable
Anorexia
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R63.1
Billable
Polydipsia
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R63.2
Billable
Polyphagia
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R63.3
Billable
Feeding difficulties
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R63.30
Billable
Feeding difficulties, unspecified
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R63.31
Billable
Pediatric feeding disorder, acute
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R63.32
Billable
Pediatric feeding disorder, chronic
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R63.39
Billable
Other feeding difficulties
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R63.4
Billable
Abnormal weight loss
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R63.5
Billable
Abnormal weight gain
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R63.6
Billable
Underweight
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R63.8
Billable
Other symptoms and signs concerning food and fluid intake
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R64
Billable
Cachexia
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R65
Billable
Symptoms and signs specifically associated with systemic inflammation and infection
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R65.1
Billable
Systemic inflammatory response syndrome (SIRS) of non-infectious origin
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R65.10
Billable
Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
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R65.11
Billable
Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
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R65.2
Billable
Severe sepsis
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R65.20
Billable
Severe sepsis without septic shock
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R65.21
Billable
Severe sepsis with septic shock
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R68
Other general symptoms and signs
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R68.0
Billable
Hypothermia, not associated with low environmental temperature
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R68.1
Billable
Nonspecific symptoms peculiar to infancy
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R68.11
Billable
Excessive crying of infant (baby)
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R68.12
Billable
Fussy infant (baby)
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R68.13
Billable
Apparent life threatening event in infant (ALTE)
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R68.19
Billable
Other nonspecific symptoms peculiar to infancy
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R68.2
Billable
Dry mouth, unspecified
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R68.3
Billable
Clubbing of fingers
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R68.8
Billable
Other general symptoms and signs
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R68.81
Billable
Early satiety
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R68.82
Billable
Decreased libido
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R68.83
Billable
Chills (without fever)
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R68.84
Billable
Jaw pain
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R68.89
Billable
Other general symptoms and signs
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R69
Billable
Illness, unspecified
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Updates & Changes

FY 2026 Updates

Current Year

Deleted Codes

No codes deleted in this range for FY 2026

No significant changes for FY 2026

This range maintains stability with current coding practices

Historical Changes

  • •FY 2025: Routine maintenance updates with minor terminology clarifications
  • •FY 2024: Enhanced specificity requirements for certain code ranges
  • •FY 2023: Updated documentation guidelines for improved clarity

Upcoming Changes

  • •Proposed updates pending review by Coordination and Maintenance Committee
  • •Under consideration: Enhanced digital health integration codes

Implementation Guidance

  • •Review all FY 2026 updates for R40-R69 codes before implementation
  • •Always verify the most current codes in the ICD-10-CM manual
  • •Ensure clinical documentation supports the selected diagnosis codes
  • +3 more guidance items...

Range Overview

high priority

The ICD-10 code range R40-R69 encompasses a variety of symptoms and signs involving cognition, perception, emotional state, and behavior. These codes are used to document symptoms and signs that are not associated directly with an underlying condition, or where a definitive diagnosis has not been established. They cover a broad spectrum of clinical presentations, from sleep disturbances (R40) to general symptoms and signs (R69).

Key Usage Points:

  • •These codes are used when a definitive diagnosis has not been established.
  • •The codes can be used in conjunction with other codes to provide a more complete clinical picture.
  • •The codes should not be used if the symptom or sign is routinely associated with a condition, and the condition is known.
  • •The codes can be used to document symptoms and signs on initial presentation, before a definitive diagnosis is made.
  • •The codes can also be used in cases where a symptom or sign is present, but it is not associated with any known condition.

Coding Guidelines

When to Use:

  • ✓When a patient presents with symptoms such as confusion or hallucinations, but no definitive diagnosis has been made.
  • ✓When a patient presents with emotional symptoms such as fear or anxiety, but no underlying condition has been identified.
  • ✓When a patient presents with perceptual disturbances, such as visual disturbances, but no definitive diagnosis has been made.
  • ✓When a patient presents with behavioral symptoms, such as aggression, but no underlying condition has been identified.

When NOT to Use:

  • ✗When the symptom or sign is routinely associated with a known condition.
  • ✗When the symptom or sign is a known side effect of a medication the patient is taking.
  • ✗When the symptom or sign is a known complication of a procedure the patient has undergone.
  • ✗When the symptom or sign is a known manifestation of a disease the patient has.

Code Exclusions

Always verify exclusions in the ICD-10 manual before coding.

Documentation Requirements

Documentation for codes in the R40-R69 range should be detailed and specific, describing the symptom or sign, its severity, duration, and any factors that may influence it. The documentation should also include any relevant clinical findings, diagnostic tests, and treatments.

Clinical Information:

  • •Detailed description of the symptom or sign
  • •Severity and duration of the symptom or sign
  • •Factors influencing the symptom or sign
  • •Relevant clinical findings
  • •Diagnostic tests and treatments

Supporting Evidence:

  • •Patient's medical history
  • •Physical examination findings
  • •Results of diagnostic tests
  • •Treatment plans
Good Documentation Example:

Patient presents with severe visual disturbances lasting for two weeks. No known underlying condition. Physical examination reveals no abnormalities. MRI scheduled.

Poor Documentation Example:

Patient complains of seeing things.

Common Documentation Errors:

  • âš Not providing enough detail about the symptom or sign
  • âš Not documenting the severity or duration of the symptom or sign
  • âš Not including relevant clinical findings or diagnostic tests
  • âš Not documenting the treatment plan

Range Statistics

7
Total Codes
170
Billable
Complexity:
Medium
Primary Use:Clinical Documentation
Chapter:18

Coding Complexity

Medium
Complexity Rating

Coding for symptoms and signs can be complex because it requires a thorough understanding of the patient's medical history, physical examination findings, and diagnostic tests. It also requires careful consideration of whether the symptom or sign has a known underlying cause, is a known side effect of a medication, or is a known complication of a procedure.

Key Factors:
  • â–¸Determining whether a symptom or sign has a known underlying cause
  • â–¸Determining whether a symptom or sign is a known side effect of a medication or a known complication of a procedure
  • â–¸Determining the severity and duration of the symptom or sign
  • â–¸Documenting all relevant clinical findings, diagnostic tests, and treatments

Specialty Focus

While these codes can be used in any medical specialty, they are particularly relevant in psychiatry, neurology, and primary care, where patients often present with symptoms and signs that do not have a clear underlying cause.

Primary Specialties:
Psychiatry
30%
Neurology
30%
Primary Care
40%
Clinical Scenarios:
  • • A patient presents with hallucinations, but no underlying condition has been identified.
  • • A patient presents with severe anxiety, but no underlying condition has been identified.
  • • A patient presents with aggression, but no underlying condition has been identified.
  • • A patient presents with visual disturbances, but no underlying condition has been identified.
  • • A patient presents with confusion, but no underlying condition has been identified.

Resources & References

There are many resources available for coding symptoms and signs, including the ICD-10 manual, official coding guidelines, and clinical reference materials.

Official Guidelines:

  • ICD-10-CM Official Guidelines for Coding and Reporting
  • American Health Information Management Association (AHIMA) Coding Guidelines
  • Centers for Medicare & Medicaid Services (CMS) Coding Guidelines

Clinical References:

  • American Medical Association (AMA) Clinical Guidelines
  • UpToDate Clinical Guidelines

Educational Materials:

  • AHIMA ICD-10 Training Materials
  • CMS ICD-10 Training Materials

Frequently Asked Questions

Can I use a code from the R40-R69 range if the symptom or sign is a known side effect of a medication the patient is taking?

No, if the symptom or sign is a known side effect of a medication, it should be coded with the appropriate code for the side effect, not with a code from the R40-R69 range.