Toxic effects of substances chiefly nonmedicinal as to source
ICD-10 Codes (200)
T52T52.0T52.1T52.2T52.3T52.4T52.8T52.9T52.91T52.92T52.93T52.94T53T53.0T53.1T53.2T53.3T53.4T53.5T53.6T53.7T53.9T53.91T53.92T53.93T53.94T54T54.0T54.1T54.2T54.3T54.9T54.91T54.92T54.93T54.94T55T55.0T55.1T56T56.0T56.1T56.2T56.3T56.4T56.5T56.6T56.7T56.8T56.81T56.811T56.812T56.813T56.814T56.82T56.821T56.822T56.823T56.824T56.89T56.891T56.892T56.893T56.894T56.9T56.91T56.92T56.93T56.94T57T57.0T57.1T57.2T57.3T57.8T57.9T57.91T57.92T57.93T57.94T58T58.0T58.01T58.02T58.03T58.04T58.1T58.11T58.12T58.13T58.14T58.2T58.8T58.9T58.91T58.92T58.93T58.94T59T59.0T59.1T59.2T59.3T59.4T59.5T59.6T59.7T59.8T59.81T59.811T59.812T59.813T59.814T59.89T59.891T59.892T59.893T59.894T59.9T59.91T59.92T59.93T59.94T60T60.0T60.1T60.2T60.3T60.4T60.8T60.9T60.91T60.92T60.93T60.94T61T61.0T61.01T61.02T61.03T61.04T61.1T61.11T61.12T61.13T61.14T61.7T61.77T61.771T61.772T61.773T61.774T61.78T61.781T61.782T61.783T61.784T61.8T61.9T61.91T61.92T61.93T61.94T62T62.0T62.1T62.2T62.8T62.9T62.91T62.92T62.93T62.94T63T63.0T63.00T63.001T63.002T63.003T63.004T63.01T63.011T63.012T63.013T63.014T63.02T63.021T63.022T63.023T63.024T63.03T63.031T63.032T63.033T63.034T63.04T63.041T63.042T63.043T63.044Updates & Changes
FY 2026 Updates
New Codes (2)
Revised Codes (1)
Deleted Codes
No codes deleted in this range for FY 2026
Historical Changes
- •FY 2025: Routine maintenance updates with minor terminology clarifications
- •FY 2024: Enhanced specificity requirements for certain code ranges
- •FY 2023: Updated documentation guidelines for improved clarity
Upcoming Changes
- •Proposed updates pending review by Coordination and Maintenance Committee
- •Under consideration: Enhanced digital health integration codes
Implementation Guidance
- •Review all FY 2026 updates for T51-T65 codes before implementation
- •Always verify the most current codes in the ICD-10-CM manual
- •Ensure clinical documentation supports the selected diagnosis codes
- +3 more guidance items...
Range Overview
The ICD-10 category T51-T65 encompasses codes for toxic effects of substances chiefly nonmedicinal as to source. These codes are used to document cases where patients have been exposed to harmful substances, including alcohol, drugs, heavy metals, and other toxins, which are not typically considered medicinal. They cover both acute and chronic conditions, and can include intentional and unintentional exposures, as well as adverse effects in therapeutic use and complications of care.
Key Usage Points:
- •Always code for the specific substance involved in the toxic exposure.
- •Include additional codes for all associated manifestations.
- •Use additional code(s) for any personal history of substance abuse.
- •For adverse effects in therapeutic use, assign first the code for the nature of the adverse effect, followed by the code for the toxic effect.
- •For underdosing, assign the code from categories T36-T50 first, followed by the code for the condition for which the drug was prescribed.
Coding Guidelines
When to Use:
- ✓When a patient presents with symptoms due to exposure to a toxic substance.
- ✓When a patient has a known history of substance abuse and presents with related complications.
- ✓When a patient has an adverse reaction to a substance used in therapeutic doses.
- ✓When a patient is seen for follow-up care after treatment for toxic exposure.
- ✓When a patient is seen for complications of care related to treatment for toxic exposure.
When NOT to Use:
- ✗When a patient has a reaction to a medication prescribed for therapeutic use (use adverse effect codes instead).
- ✗When a patient has a reaction to a substance that is typically considered medicinal (use poisoning codes instead).
- ✗When a patient has a condition that is due to long-term exposure to a substance (use chronic exposure codes instead).
- ✗When a patient has a condition that is due to a substance that is not typically considered toxic (use other codes as appropriate).
Code Exclusions
Always verify exclusions with the patient's medical record and the official ICD-10 coding guidelines.
Documentation Requirements
Documentation for codes in the T51-T65 range should include the specific substance involved, the nature of the exposure (acute, chronic, intentional, unintentional, adverse effect in therapeutic use, underdosing), and all associated manifestations. It should also include any relevant history of substance abuse and any complications of care.
Clinical Information:
- •Specific substance involved
- •Nature of exposure
- •Associated manifestations
- •History of substance abuse
- •Complications of care
Supporting Evidence:
- •Laboratory test results
- •Imaging studies
- •Physician's clinical notes
- •Emergency medical services report
Good Documentation Example:
Patient presented with acute respiratory distress and confusion after unintentional ingestion of a cleaning product. Lab tests confirmed toxic exposure. Patient has a history of dementia.
Poor Documentation Example:
Patient presented with breathing problems and confusion.
Common Documentation Errors:
- âš Not specifying the substance involved
- âš Not documenting the nature of the exposure
- âš Not including codes for all associated manifestations
- âš Not including codes for history of substance abuse when relevant
- âš Not including codes for complications of care when relevant
Range Statistics
Coding Complexity
Coding for toxic effects of substances chiefly nonmedicinal as to source can be complex due to the need to identify the specific substance involved, determine the nature of the exposure, identify all associated manifestations, and include codes for any relevant history of substance abuse and any complications of care. However, with careful review of the patient's medical record and the official ICD-10 coding guidelines, these codes can be applied accurately and effectively.
Key Factors:
- â–¸Identifying the specific substance involved
- â–¸Determining the nature of the exposure
- â–¸Identifying all associated manifestations
- â–¸Identifying any relevant history of substance abuse
- â–¸Identifying any complications of care
Specialty Focus
These codes are most commonly used in emergency medicine, toxicology, and occupational medicine. They may also be used in other specialties when patients present with conditions related to toxic exposure.
Primary Specialties:
Clinical Scenarios:
- • A patient presents to the ER with acute respiratory distress and confusion after unintentionally ingesting a cleaning product.
- • A patient is seen in an occupational medicine clinic for chronic respiratory symptoms due to long-term exposure to asbestos in the workplace.
- • A patient is seen in a toxicology clinic for follow-up care after treatment for lead poisoning.
- • A patient with a history of alcohol abuse is seen in a primary care clinic for liver damage related to chronic alcohol use.
- • A patient is seen in the ER for complications of care after treatment for toxic exposure.
Resources & References
There are many resources available to help with coding for toxic effects of substances chiefly nonmedicinal as to source. These include the official ICD-10 coding guidelines, clinical reference materials, and educational materials from professional coding organizations.
Official Guidelines:
- ICD-10-CM Official Guidelines for Coding and Reporting
- World Health Organization (WHO) ICD-10 guidelines
- Centers for Disease Control and Prevention (CDC) ICD-10 resources
Clinical References:
- American College of Medical Toxicology resources
- American Academy of Clinical Toxicology resources
Educational Materials:
- American Health Information Management Association (AHIMA) ICD-10 training materials
- American Academy of Professional Coders (AAPC) ICD-10 resources
Frequently Asked Questions
How do I code for a patient with an adverse reaction to a substance used in therapeutic doses?
First, assign the code for the nature of the adverse effect. Then, assign the code for the toxic effect of the substance.