U00-U49
High Complexity

Provisional assignment of new diseases of uncertain etiology or emergency use

Primary Specialty: Infectious Disease
Last Updated: 2025-09-09

ICD-10 Codes (6)

4 billable
1 category headers
U07
Emergency use of U07
View
U07.0
Billable
Vaping-related disorder
View
U07.1
Billable
COVID-19
View
U09
Billable
Post COVID-19 condition
View
U09.9
Billable
Post COVID-19 condition, unspecified
View
U49
View

Updates & Changes

FY 2026 Updates

Current Year

Deleted Codes

No codes deleted in this range for FY 2026

No significant changes for FY 2026

This range maintains stability with current coding practices

Historical Changes

  • FY 2025: Routine maintenance updates with minor terminology clarifications
  • FY 2024: Enhanced specificity requirements for certain code ranges
  • FY 2023: Updated documentation guidelines for improved clarity

Upcoming Changes

  • Proposed updates pending review by Coordination and Maintenance Committee
  • Under consideration: Enhanced digital health integration codes

Implementation Guidance

  • Review all FY 2026 updates for U00-U49 codes before implementation
  • Always verify the most current codes in the ICD-10-CM manual
  • Ensure clinical documentation supports the selected diagnosis codes
  • +3 more guidance items...

Range Overview

high priority

The ICD-10 category U00-U49 is designated for the provisional assignment of new diseases of uncertain etiology or for emergency use. These codes are typically used in situations where a new disease has emerged and there is an immediate need to track cases for public health purposes. This range is unique in that it is not static, but rather evolves as new diseases are identified and classified.

Key Usage Points:

  • These codes are provisional and may change as more is learned about the disease.
  • Use U00-U49 codes to track emerging diseases for public health surveillance.
  • These codes are typically used in emergency situations.
  • The U00-U49 range is not static and evolves as new diseases are identified.
  • Always check for the most recent updates before using a code from this range.

Coding Guidelines

When to Use:

  • When a new disease has been identified and there is an immediate need to track cases.
  • When a disease of uncertain etiology has emerged and needs to be monitored.
  • In emergency situations where rapid response is required.
  • When instructed by public health authorities or official coding guidelines.

When NOT to Use:

  • When a specific code exists for the disease in another ICD-10 category.
  • When the disease has been fully classified and moved out of the U00-U49 range.
  • When the disease is not new or of uncertain etiology.
  • When not instructed by public health authorities or official coding guidelines.

Code Exclusions

Always verify exclusions with the most recent coding guidelines and updates.

Documentation Requirements

Documentation for codes in the U00-U49 range should be thorough and specific, including detailed clinical information and supporting evidence. As these codes are often used in emergency situations, documentation should be completed as quickly as possible.

Clinical Information:

  • Detailed description of the patient's symptoms and condition.
  • Any known information about the disease's etiology.
  • Diagnostic tests performed and their results.
  • Treatment provided and patient's response.

Supporting Evidence:

  • Lab reports.
  • Imaging studies.
  • Consultation notes.
  • Patient's medical history.
Good Documentation Example:

Patient presented with fever, cough, and difficulty breathing. Tested positive for novel coronavirus. Admitted for treatment with antiviral drugs. Responding well to treatment.

Poor Documentation Example:

Patient has a new virus.

Common Documentation Errors:

  • Not providing enough detail about the patient's condition.
  • Failing to include all relevant clinical information.
  • Not updating documentation as more information becomes available.
  • Not checking for the most recent coding updates.

Range Statistics

2
Total Codes
4
Billable
Complexity:
High
Primary Use:Clinical Documentation
Chapter:22

Coding Complexity

High
Complexity Rating

The U00-U49 range is rated as high complexity due to the provisional nature of these codes and the need for detailed, specific documentation. Coders must stay updated with the most recent changes and be prepared for rapid changes in the patient's condition.

Key Factors:
  • The provisional nature of these codes.
  • The need to stay updated with the most recent coding changes.
  • The requirement for detailed and specific documentation.
  • The potential for rapid changes in the patient's condition.

Specialty Focus

The U00-U49 range is primarily used by infectious disease specialists, but can be used by any healthcare provider treating a patient with a new or emerging disease.

Primary Specialties:
Infectious Disease
70%
Emergency Medicine
20%
Primary Care
10%
Clinical Scenarios:
  • A patient presenting with symptoms of a new infectious disease.
  • An outbreak of an unknown disease in a community.
  • A patient with a disease of uncertain etiology that needs to be tracked.
  • An emergency situation where a new disease has emerged.

Resources & References

Resources for the U00-U49 range include the official ICD-10 coding guidelines, clinical reference sources, and educational materials on coding for new and emerging diseases.

Official Guidelines:

  • ICD-10-CM Official Guidelines for Coding and Reporting
  • World Health Organization (WHO) coding guidelines
  • Centers for Disease Control and Prevention (CDC) coding guidelines

Clinical References:

  • UpToDate
  • Medscape

Educational Materials:

  • American Health Information Management Association (AHIMA) coding resources
  • American Academy of Professional Coders (AAPC) coding resources

Frequently Asked Questions

When should I use a code from the U00-U49 range?

Use a code from the U00-U49 range when a new disease has been identified and there is an immediate need to track cases, or when a disease of uncertain etiology has emerged and needs to be monitored.