Primary biliary cirrhosis
ICD-10 K74.3 is a billable code used to indicate a diagnosis of primary biliary cirrhosis.
Primary biliary cirrhosis (PBC), now more commonly referred to as primary biliary cholangitis, is a chronic autoimmune liver disease characterized by the progressive destruction of the small bile ducts within the liver. This condition leads to cholestasis, fibrosis, and ultimately cirrhosis. Clinically, patients may present with fatigue, pruritus, and jaundice, often accompanied by elevated alkaline phosphatase levels. The disease predominantly affects middle-aged women and is associated with other autoimmune disorders such as Sjögren's syndrome and rheumatoid arthritis. As the disease progresses, patients may develop complications related to cirrhosis, including portal hypertension and liver failure. Diagnosis typically involves serological tests for antimitochondrial antibodies (AMA) and liver biopsy to assess the degree of fibrosis. Imaging studies may also be utilized to evaluate bile duct patency and liver architecture. Early diagnosis and management are crucial to slow disease progression and improve quality of life.
Standard ICD-10-CM documentation requirements apply
Various clinical presentations within this specialty area
Follow specialty-specific billing guidelines
Standard ICD-10-CM documentation requirements apply
Various clinical presentations within this specialty area
Follow specialty-specific billing guidelines
K74.3 specifically covers primary biliary cirrhosis, characterized by autoimmune destruction of bile ducts, leading to cholestasis and liver damage. It is important to differentiate it from secondary biliary cirrhosis and other liver diseases.
K74.3 should be used when the diagnosis of primary biliary cirrhosis is confirmed through serological testing for AMA and clinical presentation. It should not be used for other forms of cirrhosis or liver disease without autoimmune features.
Documentation for K74.3 should include clinical findings, laboratory results indicating elevated alkaline phosphatase and positive AMA, and any imaging studies performed. A liver biopsy report may also be necessary to confirm the diagnosis.
