ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
DiagnosesAbnormal Antinuclear Antibody

Abnormal Antinuclear Antibody

ICD-10 Coding for Abnormal Antinuclear Antibody(R76.0, R76.8)

PRIMARY SPECIALTYRheumatology
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Abnormal Antinuclear Antibody?
Essential facts and insights about Abnormal Antinuclear Antibody

Key Clinical Considerations:

  • Presence of abnormal levels of antinuclear antibodies (ANA) in the blood
  • Symptoms consistent with autoimmune diseases such as fatigue, joint pain, skin rashes

Clinical Information

Clinical Criteria & Documentation Requirements

  • Detailed description of the patient's symptoms
  • Specific ANA test results, including titer and pattern
  • Any associated autoimmune disease diagnosis

Coding Guidelines

Usage Guidelines & Examples

  • R76.0 is used for abnormal levels of ANA, while R76.8 is used for other specified abnormal immunological findings in serum
  • R76.0 should not be confused with M32.1, which is the code for systemic lupus erythematosus with organ or system involvement

Code Exclusions

Important Exclusions

  • Systemic lupus erythematosus (M32.-)
  • Other specified systemic involvement of connective tissue (M35.8)

Related ICD-10 Codes

Primary Codes
R76.0
Raised antibody titer
R76.8
Other specified abnormal immunological findings in serum
Ancillary Codes
M32.9
Differential Codes
R76.8
R76.0

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Rheumatology

Specialty Applications

  • Patients with symptoms of autoimmune diseases
  • Patients with abnormal ANA test results

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Template 1

Patient presents with symptoms consistent with autoimmune disease. ANA test results show abnormal levels.

Template 2

ANA titer and pattern: [insert results]. No specific autoimmune disease diagnosed at this time.

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

Can this code be used for a patient with lupus?

No, lupus has its own specific codes (M32.-). This code is for abnormal ANA without a specific autoimmune disease diagnosis.

When should this code be used?

This code should be used when a patient has abnormal ANA test results, but no specific autoimmune disease has been diagnosed.