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v1.0.0
ICD-10 Guide
DiagnosesAids

Aids

ICD-10 Coding for AIDS(B20, Z21)

PRIMARY SPECIALTYInfectious Disease
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Aids?
Essential facts and insights about AIDS

Key Clinical Considerations:

  • Presence of HIV infection with certain specified conditions
  • Progressive systemic illness with no other identifiable cause

Clinical Information

Clinical Criteria & Documentation Requirements

  • Detailed documentation of HIV status
  • Specific documentation of AIDS-defining conditions

Coding Guidelines

Usage Guidelines & Examples

  • B20 is used when the patient has an illness attributable to HIV
  • Z21 is used when the patient is HIV positive but has no symptoms or illness attributable to HIV

Code Exclusions

Important Exclusions

  • Patients who are HIV negative
  • Patients with symptoms of AIDS but not diagnosed with HIV

Related ICD-10 Codes

Primary Codes
B20
Human immunodeficiency virus [HIV] disease
Z21
Asymptomatic human immunodeficiency virus [HIV] infection status
Ancillary Codes
B59
B20
when Pneumocystis pneumonia is present.
Differential Codes
Z21
Z21
for patients who are HIV+ but asymptomatic and without AIDS-defining conditions.
B20
B20
for symptomatic HIV or AIDS-defining conditions.

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Infectious Disease

Specialty Applications

  • Patients diagnosed with HIV and exhibiting symptoms of AIDS
  • Patients who are HIV positive but asymptomatic

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Template 1

Patient diagnosed with HIV and exhibiting symptoms of AIDS

Template 2

Patient is HIV positive but currently asymptomatic

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

Can B20 and Z21 be used together?

No, B20 and Z21 should not be used together. B20 is for symptomatic HIV infection while Z21 is for asymptomatic HIV infection.

When should this code be used?

These codes should be used when a patient has been diagnosed with HIV and is either symptomatic (B20) or asymptomatic (Z21).