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v1.0.0
ICD-10 Guide
DiagnosesGraft Versus Host Disease

Graft Versus Host Disease

ICD-10 Coding for Graft Versus Host Disease(D89.811, D89.82)

PRIMARY SPECIALTYHematology/Oncology
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Graft Versus Host Disease?
Essential facts and insights about Graft Versus Host Disease

Key Clinical Considerations:

  • Skin rash, diarrhea, liver dysfunction, and mucosal involvement
  • Biopsy showing lymphocytic infiltration, elevated liver enzymes, and stool analysis for diarrhea
  • Erythematous rash, jaundice, and oral mucositis on physical examination

Clinical Information

Clinical Criteria & Documentation Requirements

  • Patient history of stem cell transplant, onset and duration of symptoms, and response to treatment
  • Use of terms like 'acute' or 'chronic' GVHD, and specific organ involvement
  • Examples include detailed descriptions of skin lesions, liver function tests, and gastrointestinal symptoms

Coding Guidelines

Usage Guidelines & Examples

  • Follow guidelines for acute vs chronic GVHD coding.
  • Common errors include misclassifying the severity or omitting organ involvement.

Code Exclusions

Important Exclusions

  • Conditions like autoimmune diseases and infections that mimic GVHD
  • Alternative codes for other transplant-related complications

Related ICD-10 Codes

Primary Codes
T86.0
Graft-versus-host disease
Ancillary Codes
L54.0
L94.0
Differential Codes
D89.82
D89.811

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Hematology/Oncology

Specialty Applications

  • Patients post-hematopoietic stem cell transplant
  • Oncology and hematology clinical settings

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

Documentation requirements?

Document the type of transplant, onset of symptoms, and organ involvement.

Billing considerations?

Ensure accurate coding based on severity and organ involvement for appropriate reimbursement.