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v1.0.0
ICD-10 Guide
DiagnosesHypoxic Ischemic Encephalopathy

Hypoxic Ischemic Encephalopathy

ICD-10 Coding for Hypoxic Ischemic Encephalopathy(P91.60, P91.61, P91.62, P91.63)

PRIMARY SPECIALTYNeonatology
COMPLEXITYHigh
LAST UPDATED09/15/2025
Sam Tuffun, PT, DPT
Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Hypoxic Ischemic Encephalopathy?
Essential facts and insights about Hypoxic Ischemic Encephalopathy

Key Clinical Considerations:

  • Altered level of consciousness
  • Seizures
  • Abnormal muscle tone
  • Poor feeding
  • Respiratory distress

Clinical Information

Clinical Criteria & Documentation Requirements

  • Patient history including perinatal events
  • Neurological assessment findings
  • Results of imaging studies (e.g., MRI, CT)
  • Monitoring of vital signs and oxygen saturation

Coding Guidelines

Usage Guidelines & Examples

  • Use specific codes based on severity to avoid denials.
  • Common errors include using unspecified codes when specific codes are available.

Code Exclusions

Important Exclusions

  • Congenital brain malformations
  • Metabolic disorders causing encephalopathy

Related ICD-10 Codes

Primary Codes
P91.60
Hypoxic ischemic encephalopathy, unspecified
P91.61
Hypoxic ischemic encephalopathy, mild
P91.62
Hypoxic ischemic encephalopathy, moderate
P91.63
Hypoxic ischemic encephalopathy, severe
Ancillary Codes
P21.0
Differential Codes
G93.1
P91.62
P91.63

Related CPT Codes

CPT codes will be available in a future update.

Specialty Focus

Primary Specialty

Neonatology

Specialty Applications

  • Neonates with perinatal asphyxia
  • NICU settings

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

  • Comprehensive clinical documentation
  • Accurate code selection based on clinical criteria
  • Proper exclusion considerations
  • Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

  • Ensure proper documentation for billing
  • Verify code specificity requirements
  • Check for any additional codes needed
  • Review payer-specific guidelines

Common Issues

  • Insufficient clinical documentation
  • Incorrect code selection
  • Missing supporting diagnoses
  • Timing and frequency documentation

Frequently Asked Questions

What are the documentation requirements?

Document clinical signs, diagnostic tests, and treatment responses.

What are the billing considerations?

Ensure accurate coding based on severity and associated conditions.