ICD-10 Guide

Myeloma

ICD-10 Coding for Myeloma(C90.00, C90.01, C90.02)

PRIMARY SPECIALTYHematology

COMPLEXITYHigh

LAST UPDATED09/15/2025

Sam Tuffun, PT, DPT

Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Myeloma?

Essential facts and insights about Myeloma

Key Clinical Considerations:

Bone pain, fatigue, anemia, recurrent infections, renal dysfunction
Serum protein electrophoresis showing monoclonal protein, urine protein electrophoresis, bone marrow biopsy revealing abnormal plasma cells
Pallor, bone tenderness, signs of infection, renal impairment

Clinical Information

Clinical Criteria & Documentation Requirements

Patient history, physical examination findings, laboratory results, treatment plans
ICD-10-CM codes for myeloma, related conditions, and complications
Example: 'Patient diagnosed with multiple myeloma based on serum protein electrophoresis and bone marrow biopsy findings.'

Coding Guidelines

Usage Guidelines & Examples

Follow guidelines for coding complications and associated conditions.
Common errors include misclassifying the type of myeloma or omitting complications.

Code Exclusions

Important Exclusions

Plasma cell leukemia, solitary plasmacytoma
Codes for other hematological malignancies

Specialty Focus

Primary Specialty

Hematology

Specialty Applications

Adults, particularly those over 65, patients with chronic kidney disease
Oncology clinics, hematology practices, hospitals

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

Comprehensive clinical documentation
Accurate code selection based on clinical criteria
Proper exclusion considerations
Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

Ensure proper documentation for billing
Verify code specificity requirements
Check for any additional codes needed
Review payer-specific guidelines

Common Issues

Insufficient clinical documentation
Incorrect code selection
Missing supporting diagnoses
Timing and frequency documentation

Frequently Asked Questions

Documentation requirements?

Comprehensive patient history, lab results, and treatment details are required.

Billing considerations?

Ensure accurate coding to reflect the complexity of the case and any complications.

Myeloma

Diagnosis Overview

Key Clinical Considerations:

Clinical Information

Clinical Criteria & Documentation Requirements

Coding Guidelines

Usage Guidelines & Examples

Code Exclusions

Important Exclusions

Related ICD-10 Codes

Related CPT Codes

Specialty Focus

Primary Specialty

Specialty Applications

Coding Complexity

Documentation

Documentation Templates

Billing Information

Billing Considerations

Common Issues

Frequently Asked Questions

Documentation requirements?

Billing considerations?

Myeloma

Diagnosis Overview

Key Clinical Considerations:

Clinical Information

Clinical Criteria & Documentation Requirements

Coding Guidelines

Usage Guidelines & Examples

Code Exclusions

Important Exclusions

Related ICD-10 Codes

Related CPT Codes

Specialty Focus

Primary Specialty

Specialty Applications

Coding Complexity

Documentation

Documentation Templates

Billing Information

Billing Considerations

Common Issues

Frequently Asked Questions

Documentation requirements?

Billing considerations?