ICD-10 Guide

Myeloproliferative Neoplasm

ICD-10 Coding for Myeloproliferative Neoplasm(D47.1, D45)

PRIMARY SPECIALTYHematology

COMPLEXITYHigh

LAST UPDATED09/15/2025

Sam Tuffun, PT, DPT

Physical Therapist | Medical Coding & Billing Contributor

Diagnosis Overview

What is Myeloproliferative Neoplasm?

Essential facts and insights about Myeloproliferative Neoplasm

Key Clinical Considerations:

Symptoms may include fatigue, night sweats, weight loss, and splenomegaly.
Key diagnostic tests include complete blood count (CBC), bone marrow biopsy, and JAK2 mutation testing.
Physical exam findings may reveal splenomegaly, hepatomegaly, and pallor.

Clinical Information

Clinical Criteria & Documentation Requirements

Document patient's symptoms, lab results, and any imaging studies.
Use specific coding terminology such as 'polycythemia vera', 'essential thrombocythemia', or 'myelofibrosis'.
Examples include noting the presence of JAK2 mutation and any treatment plans.

Coding Guidelines

Usage Guidelines & Examples

Follow usage guidelines for each specific type of myeloproliferative neoplasm.
Common errors include misclassifying the type of neoplasm or omitting key diagnostic tests.

Code Exclusions

Important Exclusions

Excluded conditions include secondary causes of polycythemia and thrombocytosis.
Alternative codes may include those for reactive thrombocytosis or anemia.

Specialty Focus

Primary Specialty

Hematology

Specialty Applications

Adult populations, particularly those over 60 years old.
Clinical settings include hematology clinics, oncology practices, and hospitals.

Coding Complexity

High Complexity

This diagnosis requires careful attention to:

Comprehensive clinical documentation
Accurate code selection based on clinical criteria
Proper exclusion considerations
Specialty-specific coding guidelines

Documentation

Documentation Templates

Billing Information

Billing Considerations

Ensure proper documentation for billing
Verify code specificity requirements
Check for any additional codes needed
Review payer-specific guidelines

Common Issues

Insufficient clinical documentation
Incorrect code selection
Missing supporting diagnoses
Timing and frequency documentation

Frequently Asked Questions

What are the documentation requirements?

Include detailed patient history, lab results, and treatment plans.

What are the billing considerations?

Ensure accurate coding to reflect the specific type of myeloproliferative neoplasm for proper reimbursement.

Myeloproliferative Neoplasm

Diagnosis Overview

Key Clinical Considerations:

Clinical Information

Clinical Criteria & Documentation Requirements

Coding Guidelines

Usage Guidelines & Examples

Code Exclusions

Important Exclusions

Related ICD-10 Codes

Related CPT Codes

Specialty Focus

Primary Specialty

Specialty Applications

Coding Complexity

Documentation

Documentation Templates

Billing Information

Billing Considerations

Common Issues

Frequently Asked Questions

What are the documentation requirements?

What are the billing considerations?

Myeloproliferative Neoplasm

Diagnosis Overview

Key Clinical Considerations:

Clinical Information

Clinical Criteria & Documentation Requirements

Coding Guidelines

Usage Guidelines & Examples

Code Exclusions

Important Exclusions

Related ICD-10 Codes

Related CPT Codes

Specialty Focus

Primary Specialty

Specialty Applications

Coding Complexity

Documentation

Documentation Templates

Billing Information

Billing Considerations

Common Issues

Frequently Asked Questions

What are the documentation requirements?

What are the billing considerations?