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ICD-10 Guide
ICD-10 CodesA22.1

A22.1

Anthrax meningitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A22.1 is a billable code used to indicate a diagnosis of anthrax meningitis.

Key Diagnostic Point:

Anthrax meningitis is a severe and rare form of meningitis caused by the bacterium Bacillus anthracis, which is primarily associated with zoonotic infections. This condition arises when anthrax spores enter the central nervous system, often following a systemic infection that can originate from cutaneous, gastrointestinal, or inhalational routes. The clinical presentation may include fever, headache, neck stiffness, altered mental status, and other neurological deficits. Diagnosis is typically confirmed through cerebrospinal fluid analysis, which may reveal pleocytosis, elevated protein levels, and the presence of anthrax bacilli. Given its potential for rapid progression and high mortality rate, prompt recognition and treatment are critical. Public health considerations are paramount, as anthrax is classified as a potential bioterrorism agent, necessitating surveillance and preparedness measures in healthcare settings. Vaccination and prophylactic antibiotics are recommended for individuals at high risk of exposure, particularly in endemic areas or during outbreaks.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires knowledge of zoonotic diseases and their transmission.
  • Involves understanding of public health implications and bioterrorism concerns.
  • Diagnosis often requires specialized laboratory tests.
  • Differentiation from other forms of meningitis can be challenging.

Audit Risk Factors

  • Inadequate documentation of exposure history.
  • Failure to document laboratory confirmation.
  • Misclassification of the type of meningitis.
  • Lack of detail in clinical presentation.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, exposure risks, and laboratory results.

Common Clinical Scenarios

Patients presenting with fever and neurological symptoms after known exposure to anthrax.

Billing Considerations

Need for thorough documentation of diagnostic tests and treatment protocols.

Neurology

Documentation Requirements

Neurological examination findings and imaging results.

Common Clinical Scenarios

Patients with altered mental status and signs of meningitis.

Billing Considerations

Documentation must clearly differentiate between types of meningitis.

Coding Guidelines

Inclusion Criteria

Use A22.1 When
  • Follow official ICD
  • 10 coding guidelines, ensuring accurate documentation of the diagnosis, including the specific type of meningitis and any relevant exposure history

Exclusion Criteria

Do NOT use A22.1 When
  • Inclusion criteria involve confirmed cases of anthrax meningitis, while exclusion criteria pertain to other types of meningitis

Related CPT Codes

87070CPT Code

Culture, bacterial, any source

Clinical Scenario

Used when confirming the presence of Bacillus anthracis.

Documentation Requirements

Document the source of the culture and clinical indications.

Specialty Considerations

Infectious disease specialists should ensure thorough documentation of clinical context.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of anthrax-related conditions, improving the accuracy of epidemiological tracking and resource allocation for public health responses.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of anthrax-related conditions, improving the accuracy of epidemiological tracking and resource allocation for public health responses.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of anthrax-related conditions, improving the accuracy of epidemiological tracking and resource allocation for public health responses.

Resources

Clinical References

  • •
    CDC Anthrax Information

Coding & Billing References

  • •
    CDC Anthrax Information

Frequently Asked Questions

What are the common symptoms of anthrax meningitis?

Common symptoms include fever, severe headache, neck stiffness, altered mental status, and neurological deficits. Prompt recognition is crucial for effective treatment.