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ICD-10 Guide
ICD-10 CodesA27.81

A27.81

Aseptic meningitis in leptospirosis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A27.81 is a billable code used to indicate a diagnosis of aseptic meningitis in leptospirosis.

Key Diagnostic Point:

Aseptic meningitis in leptospirosis is a rare but serious complication of leptospirosis, a zoonotic infection caused by the Leptospira bacteria. This condition is characterized by inflammation of the protective membranes covering the brain and spinal cord, leading to symptoms such as fever, headache, neck stiffness, and altered mental status. Leptospirosis is primarily transmitted through contact with water contaminated by the urine of infected animals, particularly rodents, livestock, and wildlife. The bacteria can enter the body through mucous membranes or broken skin. Public health considerations are critical, as outbreaks can occur in areas with poor sanitation or during flooding, increasing the risk of exposure. Diagnosis typically involves serological testing and lumbar puncture to analyze cerebrospinal fluid (CSF), which may show lymphocytic pleocytosis and elevated protein levels, distinguishing it from bacterial meningitis. Prompt recognition and treatment are essential to prevent severe neurological complications.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation from other types of meningitis
  • Need for specific laboratory confirmation
  • Potential for co-infection with other zoonotic diseases
  • Variability in clinical presentation

Audit Risk Factors

  • Inadequate documentation of exposure history
  • Failure to report public health implications
  • Misdiagnosis as viral or bacterial meningitis
  • Lack of supporting lab results

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, exposure assessment, and laboratory results.

Common Clinical Scenarios

Patients presenting with fever, headache, and neurological symptoms after exposure to contaminated water.

Billing Considerations

Ensure thorough documentation of travel history and potential zoonotic exposure.

Neurology

Documentation Requirements

Neurological examination findings, CSF analysis results, and differential diagnosis considerations.

Common Clinical Scenarios

Patients with aseptic meningitis symptoms and a confirmed or suspected leptospirosis infection.

Billing Considerations

Document neurological deficits and any imaging studies performed.

Coding Guidelines

Inclusion Criteria

Use A27.81 When
  • Follow official ICD
  • 10 coding guidelines, ensuring accurate documentation of the diagnosis, including laboratory confirmation and clinical presentation

Exclusion Criteria

Do NOT use A27.81 When
  • Exclude other types of meningitis unless specified

Related CPT Codes

87490CPT Code

Leptospira serology test

Clinical Scenario

Used to confirm leptospirosis in patients with aseptic meningitis symptoms.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of leptospirosis and its complications, improving data accuracy and public health tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of leptospirosis and its complications, improving data accuracy and public health tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of leptospirosis and its complications, improving data accuracy and public health tracking.

Resources

Clinical References

  • •
    CDC Leptospirosis Information

Coding & Billing References

  • •
    CDC Leptospirosis Information

Frequently Asked Questions

What are the common symptoms of aseptic meningitis in leptospirosis?

Common symptoms include fever, headache, neck stiffness, nausea, vomiting, and altered mental status. Symptoms can vary based on the severity of the infection.