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v1.0.0
ICD-10 Guide
ICD-10 CodesA41.81

A41.81

Sepsis due to Enterococcus

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A41.81 is a billable code used to indicate a diagnosis of sepsis due to enterococcus.

Key Diagnostic Point:

Sepsis due to Enterococcus is a severe systemic infection characterized by the presence of Enterococcus bacteria in the bloodstream, leading to a dysregulated host response. Enterococcus species, particularly Enterococcus faecalis and Enterococcus faecium, are part of the normal intestinal flora but can become pathogenic, especially in immunocompromised patients or those with underlying health conditions. The clinical presentation of sepsis includes fever, chills, tachycardia, hypotension, and altered mental status. Patients may require intensive care unit (ICU) admission for close monitoring and aggressive management, including intravenous fluids, vasopressors, and broad-spectrum antibiotics. The management of sepsis due to Enterococcus is complicated by the potential for antibiotic resistance, necessitating careful antimicrobial stewardship to optimize treatment while minimizing the risk of further resistance development. Early recognition and prompt treatment are critical to improving outcomes in patients with this serious condition.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between sepsis and other severe infections
  • Identifying the specific Enterococcus species involved
  • Understanding the patient's underlying health conditions
  • Navigating antibiotic resistance issues

Audit Risk Factors

  • Inadequate documentation of the causative organism
  • Failure to document the severity of the sepsis
  • Lack of evidence for antibiotic stewardship efforts
  • Inconsistent coding of related conditions

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed microbiological data, treatment plans, and patient history.

Common Clinical Scenarios

Patients with recurrent infections, those with complex medical histories, and cases of antibiotic-resistant infections.

Billing Considerations

Documentation must clearly indicate the organism and its susceptibility profile.

Critical Care

Documentation Requirements

Comprehensive notes on patient monitoring, interventions, and response to treatment.

Common Clinical Scenarios

Patients requiring ICU admission for severe sepsis or septic shock.

Billing Considerations

Accurate recording of vital signs and treatment protocols is essential.

Coding Guidelines

Inclusion Criteria

Use A41.81 When
  • According to ICD
  • 10 guidelines, A41
  • 81 should be used when there is clear documentation of sepsis due to Enterococcus, supported by laboratory results
  • It is important to ensure that the diagnosis is confirmed and that the clinical criteria for sepsis are met

Exclusion Criteria

Do NOT use A41.81 When
No specific exclusions found.

Related CPT Codes

87070CPT Code

Culture, bacterial, any source

Clinical Scenario

Used when blood cultures are taken to identify Enterococcus.

Documentation Requirements

Document the source of the culture and results.

Specialty Considerations

Infectious disease specialists should ensure cultures are properly documented.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of sepsis, including the identification of causative organisms like Enterococcus. This specificity aids in better tracking of infection trends and antibiotic resistance patterns.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of sepsis, including the identification of causative organisms like Enterococcus. This specificity aids in better tracking of infection trends and antibiotic resistance patterns.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    CDC Guidelines for Sepsis Management

Coding & Billing References

  • •
    CDC Guidelines for Sepsis Management

Frequently Asked Questions

What is the importance of identifying Enterococcus in sepsis?

Identifying Enterococcus is crucial for appropriate antibiotic therapy, especially given the potential for resistance. It also helps in understanding the source of infection and guiding further management.