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ICD-10 Guide
ICD-10 CodesA42.1

A42.1

Actinomycotic sepsis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A42.1 is a billable code used to indicate a diagnosis of actinomycotic sepsis.

Key Diagnostic Point:

Actinomycotic sepsis is a severe systemic infection caused by Actinomyces species, which are anaerobic bacteria commonly found in the oral cavity, gastrointestinal tract, and female genital tract. This condition is particularly concerning in immunocompromised patients, such as those with HIV/AIDS, cancer, or those undergoing immunosuppressive therapy. The clinical presentation may include fever, chills, malaise, and localized abscess formation, often leading to septic shock if not promptly treated. Diagnosis can be challenging due to the nonspecific nature of symptoms and the difficulty in culturing Actinomyces, which may require specialized media and conditions. Imaging studies may reveal abscesses or other complications, but definitive diagnosis often relies on histopathological examination or culture from infected tissues. Given the opportunistic nature of this infection, timely recognition and treatment are crucial to prevent severe morbidity and mortality.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Difficulty in diagnosing due to nonspecific symptoms
  • Need for specialized culture techniques
  • Potential for misdiagnosis with other infections
  • Variability in clinical presentation among immunocompromised patients

Audit Risk Factors

  • Inadequate documentation of immunocompromised status
  • Failure to document the source of infection
  • Lack of specificity in clinical notes
  • Misclassification of the type of sepsis

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical history, laboratory results, and treatment plans must be documented.

Common Clinical Scenarios

Patients presenting with fever and abscesses, particularly in immunocompromised individuals.

Billing Considerations

Ensure that the underlying immunocompromised condition is clearly documented to support the diagnosis.

Oncology

Documentation Requirements

Documentation of cancer treatment history and current immunosuppressive therapies is essential.

Common Clinical Scenarios

Cancer patients developing infections during chemotherapy or after surgical procedures.

Billing Considerations

Document the relationship between cancer treatment and the development of actinomycotic sepsis.

Coding Guidelines

Inclusion Criteria

Use A42.1 When
  • According to ICD
  • 10 guidelines, A42
  • 1 should be used when the infection is confirmed and documented
  • It is important to include any underlying conditions that may contribute to the patient's immunocompromised state

Exclusion Criteria

Do NOT use A42.1 When
No specific exclusions found.

Related CPT Codes

87070CPT Code

Culture, bacterial, any other source

Clinical Scenario

Used when culturing for Actinomyces from abscess fluid.

Documentation Requirements

Document the source of the culture and the clinical indication.

Specialty Considerations

Infectious disease specialists should ensure that cultures are sent to appropriate labs for anaerobic bacteria.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of actinomycotic sepsis, improving the accuracy of data collection and reimbursement processes. It emphasizes the importance of documenting the causative organism and the patient's immunocompromised status.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of actinomycotic sepsis, improving the accuracy of data collection and reimbursement processes. It emphasizes the importance of documenting the causative organism and the patient's immunocompromised status.

Reimbursement & Billing Impact

reimbursement processes. It emphasizes the importance of documenting the causative organism and the patient's immunocompromised status.

Resources

Clinical References

  • •
    CDC Actinomycosis Information

Coding & Billing References

  • •
    CDC Actinomycosis Information

Frequently Asked Questions

What are the common symptoms of actinomycotic sepsis?

Common symptoms include fever, chills, malaise, and localized pain, often associated with abscess formation.

How is actinomycotic sepsis diagnosed?

Diagnosis typically involves clinical evaluation, imaging studies, and culture of the organism from infected tissues or fluids.