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ICD-10 Guide
ICD-10 CodesA48.2

A48.2

Toxic shock syndrome

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A48.2 is a billable code used to indicate a diagnosis of toxic shock syndrome.

Key Diagnostic Point:

Toxic shock syndrome (TSS) is a severe, life-threatening condition characterized by sudden onset of fever, rash, hypotension, and multi-organ dysfunction. It is often associated with the presence of certain bacterial toxins, particularly from Staphylococcus aureus and Streptococcus pyogenes. TSS can occur in both immunocompetent and immunocompromised individuals, but those with weakened immune systems are at a higher risk for opportunistic infections that can lead to TSS. The syndrome is often complicated by the presence of underlying conditions such as diabetes, HIV/AIDS, or malignancies, which can obscure the diagnosis. Diagnostic challenges arise due to the nonspecific nature of symptoms, which can mimic other conditions such as sepsis or severe allergic reactions. Early recognition and treatment are crucial, as TSS can progress rapidly, necessitating aggressive management including fluid resuscitation, antibiotic therapy, and sometimes surgical intervention to remove the source of infection. Accurate coding is essential for appropriate reimbursement and to reflect the severity of the patient's condition.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating TSS from other similar conditions like sepsis.
  • Identifying the underlying cause of TSS in immunocompromised patients.
  • Documenting the presence of opportunistic infections.
  • Understanding the clinical presentation variations in different patient populations.

Audit Risk Factors

  • Inadequate documentation of symptoms leading to TSS.
  • Failure to document underlying immunocompromised status.
  • Misclassification of TSS as a less severe infection.
  • Lack of clarity in the source of infection.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on the patient's history, presenting symptoms, and laboratory results.

Common Clinical Scenarios

Patients presenting with fever, rash, and hypotension, particularly those with a history of recent surgery or infection.

Billing Considerations

Documentation must clearly outline the causative organism and any opportunistic infections present.

Emergency Medicine

Documentation Requirements

Comprehensive assessment notes including vital signs, initial treatment provided, and response to interventions.

Common Clinical Scenarios

Patients arriving with acute febrile illness and signs of shock.

Billing Considerations

Timely documentation is critical due to the rapid progression of TSS.

Coding Guidelines

Inclusion Criteria

Use A48.2 When
  • According to ICD
  • 10 guidelines, A48
  • 2 should be used when TSS is diagnosed, and it is essential to document any underlying conditions or opportunistic infections

Exclusion Criteria

Do NOT use A48.2 When
  • Exclusion criteria include conditions that do not meet the definition of TSS

Related CPT Codes

99285CPT Code

Emergency department visit, high severity

Clinical Scenario

Used for patients presenting with TSS symptoms requiring immediate intervention.

Documentation Requirements

Detailed notes on presenting symptoms, treatment provided, and patient response.

Specialty Considerations

Emergency medicine specialists should document the urgency and severity of the condition.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like TSS, improving the accuracy of data collection and reimbursement processes. It emphasizes the need for detailed documentation to support the diagnosis.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like TSS, improving the accuracy of data collection and reimbursement processes. It emphasizes the need for detailed documentation to support the diagnosis.

Reimbursement & Billing Impact

reimbursement processes. It emphasizes the need for detailed documentation to support the diagnosis.

Resources

Clinical References

  • •
    CDC Toxic Shock Syndrome Information

Coding & Billing References

  • •
    CDC Toxic Shock Syndrome Information

Frequently Asked Questions

What are the common causes of Toxic Shock Syndrome?

Toxic Shock Syndrome is commonly caused by toxins from Staphylococcus aureus and Streptococcus pyogenes, often associated with surgical wounds, tampons, or skin infections.