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ICD-10 Guide
ICD-10 CodesA48.52

A48.52

Wound botulism

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A48.52 is a billable code used to indicate a diagnosis of wound botulism.

Key Diagnostic Point:

Wound botulism is a rare but serious form of botulism caused by the bacterium Clostridium botulinum, which produces a potent neurotoxin. This condition typically arises from contaminated wounds, particularly in individuals who inject drugs or have traumatic injuries that become infected. The neurotoxin affects the peripheral nervous system, leading to muscle paralysis, which can progress to respiratory failure if not treated promptly. Patients may present with symptoms such as weakness, dizziness, blurred vision, and difficulty swallowing or speaking. The diagnosis can be challenging, especially in immunocompromised patients who may not exhibit classic symptoms or may have atypical presentations. In these cases, a high index of suspicion is necessary, and laboratory confirmation through toxin detection in serum or wound exudate is crucial. The management of wound botulism involves supportive care, including respiratory support if needed, and the administration of botulinum antitoxin, which can mitigate the effects of the toxin if given early in the course of the illness.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation from other forms of botulism (foodborne, infant)
  • Need for laboratory confirmation of toxin presence
  • Potential for atypical presentations in immunocompromised patients
  • Documentation of wound characteristics and history of drug use

Audit Risk Factors

  • Inadequate documentation of wound characteristics
  • Failure to document history of drug use or potential exposure
  • Lack of laboratory confirmation of botulinum toxin
  • Misclassification of botulism type

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed history of exposure, clinical symptoms, and laboratory results.

Common Clinical Scenarios

Patients presenting with neurological symptoms and a history of injection drug use.

Billing Considerations

Consideration of co-infections and other opportunistic infections in immunocompromised patients.

Emergency Medicine

Documentation Requirements

Immediate assessment of neurological status and wound examination.

Common Clinical Scenarios

Acute presentations of weakness or respiratory distress in patients with suspected botulism.

Billing Considerations

Rapid identification and treatment initiation are critical to prevent complications.

Coding Guidelines

Inclusion Criteria

Use A48.52 When
  • According to ICD
  • 10 guidelines, A48
  • 52 should be used when the diagnosis of wound botulism is confirmed through clinical evaluation and laboratory testing
  • It is important to document the specific circumstances leading to the infection, including any relevant history of drug use or wound contamination

Exclusion Criteria

Do NOT use A48.52 When
No specific exclusions found.

Related CPT Codes

99285CPT Code

Emergency department visit, high severity

Clinical Scenario

Used for patients presenting with acute symptoms of botulism requiring immediate intervention.

Documentation Requirements

Detailed history, physical examination findings, and any laboratory tests performed.

Specialty Considerations

Emergency medicine specialists should document the urgency of the situation and any immediate treatments provided.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of botulism types, improving the accuracy of epidemiological data and treatment tracking. This specificity aids in better understanding the incidence and management of wound botulism.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of botulism types, improving the accuracy of epidemiological data and treatment tracking. This specificity aids in better understanding the incidence and management of wound botulism.

Reimbursement & Billing Impact

reimbursement and to avoid denials.

Resources

Clinical References

  • •
    CDC Botulism Information

Coding & Billing References

  • •
    CDC Botulism Information

Frequently Asked Questions

What are the common symptoms of wound botulism?

Common symptoms include weakness, dizziness, blurred vision, difficulty swallowing, and respiratory distress. Symptoms can vary based on the patient's overall health and immune status.