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ICD-10 Guide
ICD-10 CodesA49.01

A49.01

Methicillin susceptible Staphylococcus aureus infection, unspecified site

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A49.01 is a billable code used to indicate a diagnosis of methicillin susceptible staphylococcus aureus infection, unspecified site.

Key Diagnostic Point:

Methicillin susceptible Staphylococcus aureus (MSSA) is a type of bacteria that can cause a range of infections, from mild skin infections to more severe conditions such as pneumonia, endocarditis, and sepsis. This code is used when the infection is not specified to a particular site, which can complicate diagnosis and treatment. MSSA is particularly concerning in immunocompromised patients, such as those undergoing chemotherapy, organ transplant recipients, or individuals with HIV/AIDS, as their weakened immune systems make them more susceptible to infections. The clinical presentation can vary widely, and diagnostic challenges arise due to the need for specific cultures and sensitivity testing to confirm the presence of MSSA. In these patients, the infection may present atypically, leading to delays in diagnosis and treatment. Furthermore, the lack of specificity in the site of infection can complicate the coding process, as coders must rely on the documentation provided by healthcare providers to accurately capture the nature of the infection and its implications for treatment.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Unspecified site of infection complicates coding.
  • Requires thorough documentation to support the diagnosis.
  • Potential for misdiagnosis or underreporting in immunocompromised patients.
  • Variability in clinical presentation can lead to confusion.

Audit Risk Factors

  • Inadequate documentation of infection site.
  • Failure to specify the immunocompromised status of the patient.
  • Lack of culture results in the medical record.
  • Inconsistent terminology used by providers.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on the patient's history, physical examination findings, and laboratory results.

Common Clinical Scenarios

Patients presenting with fever, skin lesions, or respiratory symptoms without a clear source.

Billing Considerations

Ensure that the documentation clearly states the site of infection when possible, and note any immunocompromised status.

Oncology

Documentation Requirements

Comprehensive records of chemotherapy regimens and any associated complications.

Common Clinical Scenarios

Cancer patients experiencing infections during or after treatment.

Billing Considerations

Highlight the patient's immunocompromised state and any relevant lab results to support coding.

Coding Guidelines

Inclusion Criteria

Use A49.01 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation
  • The unspecified site should be justified in the medical record, and any relevant laboratory findings should be included

Exclusion Criteria

Do NOT use A49.01 When
No specific exclusions found.

Related CPT Codes

87070CPT Code

Culture, bacterial, any source

Clinical Scenario

Used when obtaining cultures to confirm MSSA infection.

Documentation Requirements

Document the source of the culture and the results.

Specialty Considerations

Infectious disease specialists should ensure that culture results are clearly linked to the diagnosis.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of infections, improving data accuracy and facilitating better patient management. A49.01 reflects the need for precise documentation to capture the nuances of MSSA infections.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of infections, improving data accuracy and facilitating better patient management. A49.01 reflects the need for precise documentation to capture the nuances of MSSA infections.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of infections, improving data accuracy and facilitating better patient management. A49.01 reflects the need for precise documentation to capture the nuances of MSSA infections.

Resources

Clinical References

  • •
    CDC Guidelines on Staphylococcus aureus Infections

Coding & Billing References

  • •
    CDC Guidelines on Staphylococcus aureus Infections

Frequently Asked Questions

What is the significance of coding MSSA infections?

Coding MSSA infections accurately is crucial for understanding the epidemiology of these infections, guiding treatment decisions, and ensuring appropriate resource allocation in healthcare settings.