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ICD-10 Guide
ICD-10 CodesA51.41

A51.41

Secondary syphilitic meningitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A51.41 is a billable code used to indicate a diagnosis of secondary syphilitic meningitis.

Key Diagnostic Point:

Secondary syphilitic meningitis is a severe manifestation of syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. This condition arises when the infection disseminates to the central nervous system, leading to inflammation of the meninges. Patients may present with symptoms such as severe headache, fever, neck stiffness, and altered mental status. Diagnosis typically involves serological testing for syphilis, lumbar puncture for cerebrospinal fluid analysis, and imaging studies to assess for complications. Treatment primarily consists of high-dose intravenous penicillin G, which is effective in eradicating the infection. Early diagnosis and treatment are crucial to prevent long-term neurological damage. Contact tracing is essential to identify and treat sexual partners, thereby reducing the risk of further transmission. Given the potential for serious complications, including neurological deficits, timely intervention is critical in managing this condition.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires understanding of syphilis stages and their implications.
  • Involves knowledge of neurological manifestations and their coding.
  • Differentiation from other types of meningitis is necessary.
  • Documentation must clearly indicate the secondary nature of the condition.

Audit Risk Factors

  • Inadequate documentation of neurological symptoms.
  • Failure to document serological test results.
  • Lack of clarity on the secondary nature of the condition.
  • Improper linkage between diagnosis and treatment codes.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, serological test results, and treatment plans.

Common Clinical Scenarios

Patients presenting with neurological symptoms and a history of syphilis.

Billing Considerations

Ensure all relevant tests and treatments are documented to support coding.

Neurology

Documentation Requirements

Neurological examination findings, imaging results, and treatment responses.

Common Clinical Scenarios

Patients with altered mental status and confirmed syphilis infection.

Billing Considerations

Documenting the neurological impact of syphilis is crucial for accurate coding.

Coding Guidelines

Inclusion Criteria

Use A51.41 When
  • Follow official coding guidelines for syphilis and meningitis
  • Ensure that documentation supports the diagnosis of secondary syphilitic meningitis, including serological confirmation and clinical symptoms

Exclusion Criteria

Do NOT use A51.41 When
No specific exclusions found.

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used to confirm syphilis diagnosis in patients with neurological symptoms.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of diagnoses and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of diagnoses and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of diagnoses and treatment tracking.

Resources

Clinical References

  • •
    CDC Syphilis Fact Sheet

Coding & Billing References

  • •
    CDC Syphilis Fact Sheet

Frequently Asked Questions

What are the symptoms of secondary syphilitic meningitis?

Symptoms include severe headache, fever, neck stiffness, and altered mental status, which may vary in severity.

How is secondary syphilitic meningitis diagnosed?

Diagnosis is made through serological testing for syphilis and lumbar puncture to analyze cerebrospinal fluid.

What is the treatment for secondary syphilitic meningitis?

Treatment typically involves high-dose intravenous penicillin G, which is effective in treating the infection.