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ICD-10 Guide
ICD-10 CodesA51.46

A51.46

Secondary syphilitic osteopathy

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A51.46 is a billable code used to indicate a diagnosis of secondary syphilitic osteopathy.

Key Diagnostic Point:

Secondary syphilitic osteopathy is a manifestation of secondary syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. This condition typically arises after the initial primary stage of syphilis, characterized by the appearance of a painless ulcer known as a chancre. In the secondary stage, systemic dissemination of the bacteria occurs, leading to a variety of symptoms, including skin rashes, mucous membrane lesions, and lymphadenopathy. Osteopathy, or bone disease, can occur as a result of the inflammatory response to the infection, leading to bone pain, swelling, and potential deformities. Diagnosis is primarily clinical, supported by serological tests such as the rapid plasma reagin (RPR) and treponemal tests. Treatment involves the administration of antibiotics, typically benzathine penicillin G, which is effective in eradicating the infection and preventing further complications. Early detection and treatment are crucial to prevent long-term sequelae, including tertiary syphilis, which can lead to more severe systemic involvement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires understanding of syphilis stages and manifestations.
  • Differentiation from other osteopathic conditions.
  • Need for accurate documentation of clinical findings.
  • Potential for co-infection with other STIs.

Audit Risk Factors

  • Inadequate documentation of clinical findings.
  • Failure to document treatment response.
  • Misclassification of syphilis stage.
  • Lack of follow-up notes on patient progress.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, serological test results, and treatment plans.

Common Clinical Scenarios

Patients presenting with systemic symptoms of syphilis, including osteopathy.

Billing Considerations

Need for thorough documentation of sexual history and potential exposure.

Orthopedics

Documentation Requirements

Imaging studies, physical examination findings, and treatment interventions.

Common Clinical Scenarios

Patients with bone pain and swelling attributed to secondary syphilis.

Billing Considerations

Differentiating syphilitic osteopathy from other orthopedic conditions.

Coding Guidelines

Inclusion Criteria

Use A51.46 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the condition's clinical manifestations
  • Include relevant history of syphilis and any associated complications

Exclusion Criteria

Do NOT use A51.46 When
  • Exclude codes for primary syphilis unless documented

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used to confirm diagnosis of syphilis in patients presenting with osteopathy.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive STI screening.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of epidemiological data and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of epidemiological data and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of epidemiological data and treatment tracking.

Resources

Clinical References

  • •
    CDC Syphilis Fact Sheet

Coding & Billing References

  • •
    CDC Syphilis Fact Sheet

Frequently Asked Questions

What are the common symptoms of secondary syphilitic osteopathy?

Common symptoms include bone pain, swelling, and systemic signs such as fever and rash. Patients may also present with lymphadenopathy.