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v1.0.0
ICD-10 Guide
ICD-10 CodesA52.0

A52.0

Early syphilis, symptomatic

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A52.0 is a billable code used to indicate a diagnosis of early syphilis, symptomatic.

Key Diagnostic Point:

Early syphilis, symptomatic, refers to the initial stage of syphilis infection characterized by the presence of symptoms such as primary chancre, secondary lesions, or systemic manifestations. This stage typically occurs within the first year of infection and is marked by the appearance of a painless ulcer (chancre) at the site of infection, often accompanied by lymphadenopathy. Secondary syphilis may present with a rash, mucous membrane lesions (such as mucous membrane pemphigoid), and flu-like symptoms. Early diagnosis and treatment are crucial to prevent progression to later stages of syphilis, which can lead to severe complications affecting multiple organ systems. The diagnosis is confirmed through serological testing, including non-treponemal tests (e.g., RPR, VDRL) and treponemal tests (e.g., FTA-ABS). Treatment typically involves the administration of benzathine penicillin G, with follow-up serological testing to ensure treatment efficacy.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between primary and secondary syphilis symptoms
  • Understanding serological testing results and their implications
  • Documenting the presence of symptoms accurately
  • Navigating treatment guidelines and follow-up requirements

Audit Risk Factors

  • Inadequate documentation of symptoms
  • Failure to include serological test results
  • Misclassification of syphilis stage
  • Lack of follow-up documentation

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on symptoms, test results, and treatment plans.

Common Clinical Scenarios

Patients presenting with genital ulcers, rashes, or systemic symptoms.

Billing Considerations

Ensure all serological tests are documented and interpreted correctly.

Primary Care

Documentation Requirements

Comprehensive patient history, including sexual history and risk factors.

Common Clinical Scenarios

Routine screenings in high-risk populations and symptomatic patients.

Billing Considerations

Documenting patient education on STI prevention and follow-up care.

Coding Guidelines

Inclusion Criteria

Use A52.0 When
  • According to ICD
  • 10 guidelines, A52
  • 0 should be used when the patient presents with symptoms indicative of early syphilis
  • Coders must ensure that the diagnosis is supported by clinical documentation and serological testing results

Exclusion Criteria

Do NOT use A52.0 When
  • Exclusion criteria include documented cases of late syphilis or other STIs that may mimic symptoms

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used when testing for syphilis in symptomatic patients.

Documentation Requirements

Document the reason for testing and the results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing protocols are followed.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving the accuracy of epidemiological data and treatment tracking. A52.0 provides a clear distinction for early symptomatic cases, facilitating better management and follow-up.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving the accuracy of epidemiological data and treatment tracking. A52.0 provides a clear distinction for early symptomatic cases, facilitating better management and follow-up.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving the accuracy of epidemiological data and treatment tracking. A52.0 provides a clear distinction for early symptomatic cases, facilitating better management and follow-up.

Resources

Clinical References

  • •
    CDC Syphilis Treatment Guidelines

Coding & Billing References

  • •
    CDC Syphilis Treatment Guidelines

Frequently Asked Questions

What are the common symptoms of early syphilis?

Common symptoms include a painless ulcer (chancre), swollen lymph nodes, and systemic symptoms such as fever and rash.

How is early syphilis diagnosed?

Diagnosis is made through clinical evaluation and serological testing, including both non-treponemal and treponemal tests.

What is the recommended treatment for early syphilis?

The standard treatment is benzathine penicillin G, administered intramuscularly, with follow-up serological testing to confirm treatment success.