ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesA52.1

A52.1

Early syphilis, symptomatic

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A52.1 is a billable code used to indicate a diagnosis of early syphilis, symptomatic.

Key Diagnostic Point:

Early syphilis, symptomatic, refers to the initial stage of syphilis infection characterized by the presence of symptoms such as primary chancre, secondary rash, or mucous membrane lesions. This stage typically occurs within weeks to months after exposure to the Treponema pallidum bacterium. Symptoms may include painless sores at the site of infection, generalized rash, fever, and swollen lymph nodes. Early diagnosis and treatment are crucial to prevent progression to later stages of syphilis, which can lead to severe complications affecting multiple organ systems. The symptomatic nature of this condition necessitates careful clinical evaluation and appropriate laboratory testing, including serological tests for syphilis, to confirm the diagnosis. Treatment usually involves the administration of benzathine penicillin G, which is effective in eradicating the infection. Contact tracing is essential to identify and treat sexual partners to prevent further transmission of the disease.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of presenting symptoms that may overlap with other conditions
  • Need for accurate serological testing and interpretation
  • Potential for co-infection with other STIs
  • Importance of thorough patient history and contact tracing

Audit Risk Factors

  • Inadequate documentation of symptoms
  • Failure to document patient history and risk factors
  • Lack of follow-up on treatment efficacy
  • Insufficient detail in contact tracing efforts

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, symptom description, and treatment plan.

Common Clinical Scenarios

Patients presenting with genital ulcers, rashes, or systemic symptoms.

Billing Considerations

Consideration of co-infections and comprehensive STI screening.

Primary Care

Documentation Requirements

Thorough documentation of sexual history and risk assessment.

Common Clinical Scenarios

Routine screenings in high-risk populations and symptomatic patients.

Billing Considerations

Importance of patient education on STI prevention and treatment adherence.

Coding Guidelines

Inclusion Criteria

Use A52.1 When
  • According to the official coding guidelines, A52
  • 1 should be used when the patient presents with symptoms indicative of early syphilis
  • Coders must ensure that documentation supports the diagnosis and that any relevant laboratory results are included

Exclusion Criteria

Do NOT use A52.1 When
  • Exclusion criteria include cases where syphilis is not the primary diagnosis or when symptoms are attributed to other conditions

Related CPT Codes

86592CPT Code

Syphilis serology

Clinical Scenario

Used for confirming diagnosis in symptomatic patients.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists may require additional tests for co-infections.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of syphilis, improving the accuracy of data collection and treatment tracking. A52.1 provides a clear distinction between symptomatic and asymptomatic cases, aiding in public health reporting and management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of syphilis, improving the accuracy of data collection and treatment tracking. A52.1 provides a clear distinction between symptomatic and asymptomatic cases, aiding in public health reporting and management.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of syphilis, improving the accuracy of data collection and treatment tracking. A52.1 provides a clear distinction between symptomatic and asymptomatic cases, aiding in public health reporting and management.

Resources

Clinical References

  • •
    CDC Syphilis Fact Sheet

Coding & Billing References

  • •
    CDC Syphilis Fact Sheet

Frequently Asked Questions

What are the common symptoms of early syphilis?

Common symptoms include painless sores, rashes, fever, and swollen lymph nodes. Symptoms may vary among individuals.