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ICD-10 Guide
ICD-10 CodesA52.12

A52.12

Other cerebrospinal syphilis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A52.12 is a billable code used to indicate a diagnosis of other cerebrospinal syphilis.

Key Diagnostic Point:

Other cerebrospinal syphilis refers to a specific manifestation of syphilis that affects the central nervous system, particularly the cerebrospinal fluid (CSF). This condition is a late-stage complication of untreated syphilis, which is caused by the bacterium Treponema pallidum. Patients may present with a range of neurological symptoms, including headaches, altered mental status, seizures, and other cognitive impairments. Diagnosis typically involves lumbar puncture to analyze CSF for the presence of the pathogen or specific antibodies. Treatment usually consists of high-dose intravenous penicillin G, which is effective in eradicating the infection. It is crucial for healthcare providers to conduct thorough sexual history assessments and contact tracing to identify and treat sexual partners, thereby preventing further transmission of syphilis. Regular follow-up and monitoring of CSF parameters are also essential to assess treatment efficacy and manage any potential complications.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires understanding of syphilis stages and complications.
  • Involves knowledge of cerebrospinal fluid analysis.
  • Differentiation from other neurological conditions.
  • Need for accurate documentation of symptoms and treatment.

Audit Risk Factors

  • Inadequate documentation of neurological symptoms.
  • Failure to document lumbar puncture results.
  • Misclassification of syphilis stage.
  • Lack of follow-up documentation post-treatment.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed history of syphilis infection, treatment history, and neurological assessment.

Common Clinical Scenarios

Patients presenting with neurological symptoms and a history of syphilis.

Billing Considerations

Ensure comprehensive documentation of all symptoms and treatment responses.

Neurology

Documentation Requirements

Neurological examination findings, CSF analysis results, and treatment plans.

Common Clinical Scenarios

Patients with altered mental status or seizures with a known syphilis history.

Billing Considerations

Document differential diagnoses to support coding.

Coding Guidelines

Inclusion Criteria

Use A52.12 When
  • Follow ICD
  • CM guidelines for coding syphilis, ensuring accurate documentation of the condition's stage and any neurological involvement
  • Include relevant symptoms and diagnostic procedures in the medical record

Exclusion Criteria

Do NOT use A52.12 When
No specific exclusions found.

Related CPT Codes

62270CPT Code

Lumbar puncture

Clinical Scenario

Used to obtain CSF for analysis in suspected cases of cerebrospinal syphilis.

Documentation Requirements

Document indication for lumbar puncture and results of CSF analysis.

Specialty Considerations

Infectious disease specialists should ensure comprehensive documentation of the patient's history and neurological status.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of data collection and treatment tracking for cerebrospinal syphilis.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of data collection and treatment tracking for cerebrospinal syphilis.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of data collection and treatment tracking for cerebrospinal syphilis.

Resources

Clinical References

  • •
    CDC Syphilis Treatment Guidelines

Coding & Billing References

  • •
    CDC Syphilis Treatment Guidelines

Frequently Asked Questions

What are the common symptoms of cerebrospinal syphilis?

Common symptoms include headaches, confusion, seizures, and other neurological deficits. Patients may also experience changes in behavior or cognitive function.