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ICD-10 Guide
ICD-10 CodesA52.13

A52.13

Late syphilitic meningitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A52.13 is a billable code used to indicate a diagnosis of late syphilitic meningitis.

Key Diagnostic Point:

Late syphilitic meningitis is a severe manifestation of tertiary syphilis, occurring typically years after the initial infection with Treponema pallidum. This condition is characterized by inflammation of the meninges, which can lead to significant neurological impairment. Patients may present with symptoms such as headache, fever, neck stiffness, altered mental status, and focal neurological deficits. Diagnosis is often confirmed through cerebrospinal fluid (CSF) analysis, which may show elevated white blood cell counts, elevated protein levels, and positive serological tests for syphilis. Late syphilitic meningitis can lead to serious complications, including seizures, cognitive decline, and even death if left untreated. Treatment typically involves high-dose intravenous penicillin, which is effective in eradicating the infection and preventing further neurological damage. Close monitoring and follow-up are essential to assess treatment efficacy and manage any residual neurological deficits.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires understanding of syphilis stages and their complications.
  • Differentiation from other types of meningitis.
  • Need for accurate documentation of neurological symptoms.
  • Potential for co-infection with other STIs.

Audit Risk Factors

  • Inadequate documentation of neurological symptoms.
  • Failure to document CSF analysis results.
  • Misclassification of the stage of syphilis.
  • Lack of follow-up documentation post-treatment.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed history of syphilis infection, treatment history, and neurological assessment.

Common Clinical Scenarios

Patients presenting with neurological symptoms and a history of syphilis.

Billing Considerations

Ensure all serological tests and CSF findings are documented.

Neurology

Documentation Requirements

Comprehensive neurological examination findings and imaging results.

Common Clinical Scenarios

Patients with cognitive decline or seizures with a history of syphilis.

Billing Considerations

Document any neurological deficits and their impact on daily functioning.

Coding Guidelines

Inclusion Criteria

Use A52.13 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation
  • Include any relevant laboratory results and treatment plans

Exclusion Criteria

Do NOT use A52.13 When
No specific exclusions found.

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used to confirm syphilis diagnosis in patients with neurological symptoms.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of late syphilitic meningitis, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of late syphilitic meningitis, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    CDC Syphilis Treatment Guidelines

Coding & Billing References

  • •
    CDC Syphilis Treatment Guidelines

Frequently Asked Questions

What are the common symptoms of late syphilitic meningitis?

Common symptoms include severe headaches, fever, neck stiffness, altered mental status, and focal neurological deficits.

How is late syphilitic meningitis diagnosed?

Diagnosis is typically made through clinical evaluation, cerebrospinal fluid analysis, and serological testing for syphilis.

What is the treatment for late syphilitic meningitis?

The standard treatment is high-dose intravenous penicillin, which is effective in treating the infection.