ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesA52.74

A52.74

Syphilis of liver and other viscera

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A52.74 is a billable code used to indicate a diagnosis of syphilis of liver and other viscera.

Key Diagnostic Point:

Syphilis of the liver and other viscera is a manifestation of tertiary syphilis, which occurs when the Treponema pallidum bacterium, responsible for syphilis, spreads to various organs after the initial stages of the infection have progressed untreated. This condition can lead to significant liver damage, presenting as hepatitis, cirrhosis, or even liver failure. Patients may exhibit symptoms such as jaundice, abdominal pain, and ascites. Diagnosis typically involves serological testing for syphilis antibodies, liver function tests, and imaging studies to assess liver involvement. Treatment primarily consists of antibiotic therapy, usually with benzathine penicillin G, which is effective in eradicating the infection and preventing further organ damage. Close monitoring of liver function and follow-up serological testing is essential to ensure treatment efficacy and manage any complications that may arise.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires understanding of syphilis stages and organ involvement
  • Need for accurate documentation of liver function tests
  • Potential for co-infections with other STIs
  • Differentiation from other liver diseases

Audit Risk Factors

  • Inadequate documentation of serological test results
  • Failure to document treatment response
  • Lack of follow-up notes on liver function
  • Misclassification of liver involvement severity

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed history of syphilis infection, treatment history, and follow-up care.

Common Clinical Scenarios

Patients presenting with late-stage syphilis and liver dysfunction.

Billing Considerations

Ensure comprehensive documentation of all symptoms and lab results to support coding.

Gastroenterology

Documentation Requirements

Liver function tests, imaging results, and treatment plans.

Common Clinical Scenarios

Patients with liver cirrhosis secondary to syphilis.

Billing Considerations

Document any liver biopsies or additional diagnostic procedures performed.

Coding Guidelines

Inclusion Criteria

Use A52.74 When
  • According to ICD
  • 10 coding guidelines, A52
  • 74 should be used when syphilis has been confirmed and there is documented involvement of the liver or other viscera
  • It is important to ensure that the diagnosis is supported by appropriate clinical documentation and laboratory results

Exclusion Criteria

Do NOT use A52.74 When
No specific exclusions found.

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used to confirm syphilis diagnosis in patients with liver involvement.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing for co-infections.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of data collection and treatment tracking. A52.74 provides a clear indication of organ involvement, which is crucial for treatment planning and epidemiological studies.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of data collection and treatment tracking. A52.74 provides a clear indication of organ involvement, which is crucial for treatment planning and epidemiological studies.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of syphilis-related conditions, improving the accuracy of data collection and treatment tracking. A52.74 provides a clear indication of organ involvement, which is crucial for treatment planning and epidemiological studies.

Resources

Clinical References

  • •
    CDC Syphilis Treatment Guidelines

Coding & Billing References

  • •
    CDC Syphilis Treatment Guidelines

Frequently Asked Questions

What are the common symptoms of syphilis of the liver?

Common symptoms include jaundice, abdominal pain, ascites, and signs of liver dysfunction such as elevated liver enzymes.

How is syphilis of the liver diagnosed?

Diagnosis is made through serological testing for syphilis antibodies, liver function tests, and imaging studies to assess liver involvement.

What is the treatment for syphilis of the liver?

Treatment typically involves antibiotic therapy, primarily benzathine penicillin G, along with monitoring liver function and managing any complications.