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ICD-10 Guide
ICD-10 CodesA52.8

A52.8

Late syphilis, other and unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A52.8 is a billable code used to indicate a diagnosis of late syphilis, other and unspecified.

Key Diagnostic Point:

Late syphilis is a stage of syphilis that occurs after the primary and secondary stages, typically occurring years after the initial infection if left untreated. It is characterized by the presence of gummas, cardiovascular syphilis, and neurosyphilis. Gummas are soft, tumor-like growths that can occur in various tissues, including skin, bones, and organs. Cardiovascular syphilis can lead to aortitis and other cardiovascular complications, while neurosyphilis can manifest as meningitis, tabes dorsalis, or general paresis. The condition is primarily transmitted through sexual contact, but can also be passed from mother to child during pregnancy. Diagnosis is made through serological testing, including non-treponemal tests (e.g., RPR, VDRL) and treponemal tests (e.g., FTA-ABS). Treatment typically involves the administration of benzathine penicillin G, with the dosage and duration depending on the stage and severity of the disease. Late syphilis can have significant health implications if not treated, including potential long-term damage to the cardiovascular and nervous systems.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between late syphilis and other stages of syphilis.
  • Understanding the various manifestations of late syphilis.
  • Need for comprehensive documentation of clinical findings.
  • Potential for co-infection with other STIs.

Audit Risk Factors

  • Inadequate documentation of clinical findings.
  • Failure to document patient history of syphilis.
  • Misclassification of syphilis stage.
  • Lack of follow-up documentation post-treatment.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on symptoms, serological test results, and treatment plans.

Common Clinical Scenarios

Patients presenting with neurological symptoms or gummas.

Billing Considerations

Consideration of co-infections and comprehensive treatment plans.

Obstetrics/Gynecology

Documentation Requirements

Documentation of maternal and fetal health, including serological testing during pregnancy.

Common Clinical Scenarios

Pregnant women with a history of syphilis requiring monitoring.

Billing Considerations

Importance of screening and treatment to prevent congenital syphilis.

Coding Guidelines

Inclusion Criteria

Use A52.8 When
  • According to ICD
  • 10 guidelines, A52
  • 8 should be used when the specific type of late syphilis is not documented
  • It is important to ensure that the diagnosis is confirmed through appropriate serological testing

Exclusion Criteria

Do NOT use A52.8 When
No specific exclusions found.

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used to confirm diagnosis of syphilis in patients presenting with symptoms.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists may require additional tests for comprehensive evaluation.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving the accuracy of data collection and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving the accuracy of data collection and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving the accuracy of data collection and treatment tracking.

Resources

Clinical References

  • •
    CDC Syphilis Treatment Guidelines

Coding & Billing References

  • •
    CDC Syphilis Treatment Guidelines

Frequently Asked Questions

What are the common symptoms of late syphilis?

Common symptoms include gummas, neurological issues, and cardiovascular problems. Patients may also be asymptomatic.

How is late syphilis treated?

Treatment typically involves benzathine penicillin G, with the dosage and duration depending on the severity of the disease.