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v1.0.0
ICD-10 Guide
ICD-10 CodesA53

A53

Syphilis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A53 is a billable code used to indicate a diagnosis of syphilis.

Key Diagnostic Point:

Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. It is characterized by distinct stages: primary, secondary, latent, and tertiary syphilis. The primary stage typically presents with a painless ulcer known as a chancre at the site of infection, which may go unnoticed. Secondary syphilis is marked by systemic manifestations such as skin rashes, mucous membrane lesions, and flu-like symptoms. If untreated, the infection can progress to latent syphilis, where no symptoms are present, and eventually to tertiary syphilis, which can cause severe complications affecting the heart, brain, and other organs. Diagnosis is primarily through serological testing, including non-treponemal tests (e.g., RPR, VDRL) and treponemal tests (e.g., FTA-ABS). Treatment typically involves the administration of benzathine penicillin G, with dosage depending on the stage of the disease. Contact tracing is crucial for preventing further transmission, as syphilis is highly contagious, especially in its early stages. Public health initiatives often focus on education, screening, and treatment to manage and control syphilis outbreaks.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of clinical presentations across different stages
  • Need for accurate serological testing interpretation
  • Potential for co-infection with other STIs
  • Importance of thorough patient history and contact tracing

Audit Risk Factors

  • Inadequate documentation of clinical findings
  • Failure to document patient history and risk factors
  • Missing serological test results in the medical record
  • Inconsistent coding of stages of syphilis

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed documentation of clinical findings, serological test results, and treatment plans.

Common Clinical Scenarios

Diagnosis and management of syphilis in patients with multiple STIs.

Billing Considerations

Ensure comprehensive documentation of patient history and risk factors for accurate coding.

Primary Care

Documentation Requirements

Thorough documentation of symptoms, risk factors, and follow-up care.

Common Clinical Scenarios

Routine screening for syphilis in high-risk populations.

Billing Considerations

Documenting patient education and counseling regarding STI prevention.

Coding Guidelines

Inclusion Criteria

Use A53 When
  • Follow official coding guidelines for STIs, ensuring accurate documentation of the stage of syphilis
  • Include relevant patient history and serological test results to support the diagnosis

Exclusion Criteria

Do NOT use A53 When
No specific exclusions found.

Related Codes

Child Codes

2 codes
A53.0
Gonococcal infection of lower genitourinary tract, unspecified
A53.9
Syphilis, unspecified

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used when testing for syphilis in patients with risk factors.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing protocols.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving data accuracy and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving data accuracy and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of syphilis stages, improving data accuracy and treatment tracking.

Resources

Clinical References

  • •
    CDC Syphilis Fact Sheet

Coding & Billing References

  • •
    CDC Syphilis Fact Sheet

Frequently Asked Questions

What are the common symptoms of syphilis?

Common symptoms include painless ulcers, rashes, and flu-like symptoms, which vary by stage.

How is syphilis treated?

Syphilis is typically treated with benzathine penicillin G, with dosage depending on the stage of the disease.