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v1.0.0
ICD-10 Guide
ICD-10 CodesA68.0

A68.0

Infections caused by Escherichia coli [E. coli] in diseases classified elsewhere

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A68.0 is a billable code used to indicate a diagnosis of infections caused by escherichia coli [e. coli] in diseases classified elsewhere.

Key Diagnostic Point:

Infections caused by Escherichia coli (E. coli) can manifest in various forms, often complicating other diseases classified under different categories. E. coli is a diverse group of bacteria, some of which are pathogenic and can lead to severe gastrointestinal infections, urinary tract infections, and other systemic infections. The pathogenic strains, such as Enterohemorrhagic E. coli (EHEC) and Enterotoxigenic E. coli (ETEC), can cause significant morbidity, particularly in vulnerable populations such as the elderly, immunocompromised individuals, and young children. The clinical presentation may vary widely, from mild diarrhea to severe hemorrhagic colitis and hemolytic uremic syndrome (HUS). The geographic distribution of E. coli infections is global, with endemic areas often linked to contaminated water sources and food products. Infections can be exacerbated by underlying conditions, making accurate coding essential for appropriate treatment and epidemiological tracking.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of clinical presentations associated with E. coli infections.
  • Potential overlap with other gastrointestinal and systemic infections.
  • Need for precise documentation of the underlying disease being classified elsewhere.
  • Variability in pathogenic strains and their associated complications.

Audit Risk Factors

  • Inadequate documentation of the underlying disease.
  • Failure to specify the strain of E. coli involved.
  • Misclassification of the infection as a primary diagnosis.
  • Lack of clarity in the clinical notes regarding the patient's symptoms and history.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on the type of E. coli infection, symptoms, and treatment response.

Common Clinical Scenarios

Patients presenting with severe diarrhea, abdominal pain, or systemic symptoms related to E. coli infections.

Billing Considerations

Consideration of travel history and exposure to contaminated food or water sources.

Gastroenterology

Documentation Requirements

Endoscopy reports, biopsy results, and detailed patient history.

Common Clinical Scenarios

Patients with chronic gastrointestinal symptoms or complications from E. coli infections.

Billing Considerations

Documentation of any co-existing gastrointestinal diseases that may complicate the infection.

Coding Guidelines

Inclusion Criteria

Use A68.0 When
  • According to ICD
  • 10 coding guidelines, A68
  • 0 should be used when E
  • coli infections are documented in the context of other diseases
  • Coders must ensure that the underlying condition is clearly stated in the medical record to justify the use of this code

Exclusion Criteria

Do NOT use A68.0 When
No specific exclusions found.

Related CPT Codes

87045CPT Code

Culture, bacterial, any source

Clinical Scenario

Used when E. coli infection is suspected and cultures are needed.

Documentation Requirements

Document the source of the culture and clinical indications.

Specialty Considerations

Infectious disease specialists may require additional tests based on patient history.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of E. coli infections, improving the accuracy of epidemiological data and treatment tracking. A68.0 provides a clear framework for documenting infections that complicate other diseases.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of E. coli infections, improving the accuracy of epidemiological data and treatment tracking. A68.0 provides a clear framework for documenting infections that complicate other diseases.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    CDC - Escherichia coli (E. coli) Infection

Coding & Billing References

  • •
    CDC - Escherichia coli (E. coli) Infection

Frequently Asked Questions

What are the common symptoms of E. coli infections?

Common symptoms include diarrhea (which may be bloody), abdominal cramps, nausea, and vomiting. In severe cases, it can lead to hemolytic uremic syndrome.