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ICD-10 Guide
ICD-10 CodesA69.2

A69.2

Other neurosyphilis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 A69.2 is a billable code used to indicate a diagnosis of other neurosyphilis.

Key Diagnostic Point:

Neurosyphilis is a complication of syphilis that affects the central nervous system. It can occur at any stage of syphilis and manifests in various forms, including asymptomatic neurosyphilis, meningovascular syphilis, and tabes dorsalis. Symptoms may include headaches, altered mental status, seizures, and sensory deficits. The condition is caused by the spirochete Treponema pallidum, which can invade the nervous system, leading to inflammation and damage. Geographic distribution of neurosyphilis is closely linked to the prevalence of syphilis, which is more common in areas with limited access to healthcare and higher rates of sexually transmitted infections. Endemic areas often include regions in sub-Saharan Africa, parts of Asia, and some urban areas in developed countries. Diagnosis typically involves serological testing for syphilis and may include lumbar puncture to analyze cerebrospinal fluid (CSF) for signs of infection. Treatment involves the use of antibiotics, primarily penicillin, which is effective in eradicating the infection and preventing further neurological damage.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of clinical presentations
  • Need for serological and CSF analysis
  • Differentiation from other neurological conditions
  • Potential for co-infection with other STIs

Audit Risk Factors

  • Inadequate documentation of symptoms
  • Failure to document serological test results
  • Misclassification of neurosyphilis type
  • Lack of follow-up documentation

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed history of syphilis infection, treatment history, and neurological symptoms.

Common Clinical Scenarios

Patients presenting with neurological symptoms and a history of syphilis.

Billing Considerations

Ensure all serological tests and CSF analyses are documented.

Neurology

Documentation Requirements

Neurological examination findings, imaging studies, and treatment plans.

Common Clinical Scenarios

Patients with unexplained neurological deficits and a history of syphilis.

Billing Considerations

Document differential diagnoses to support coding.

Coding Guidelines

Inclusion Criteria

Use A69.2 When
  • Follow the official ICD
  • CM coding guidelines for neurosyphilis, ensuring accurate documentation of the type of neurosyphilis and associated symptoms
  • Include relevant serological and CSF findings

Exclusion Criteria

Do NOT use A69.2 When
No specific exclusions found.

Related CPT Codes

86592CPT Code

Syphilis serology test

Clinical Scenario

Used to confirm syphilis diagnosis in patients with neurological symptoms.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Infectious disease specialists should ensure comprehensive testing.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of neurosyphilis, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of neurosyphilis, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    CDC Syphilis Fact Sheet

Coding & Billing References

  • •
    CDC Syphilis Fact Sheet

Frequently Asked Questions

What are the common symptoms of neurosyphilis?

Common symptoms include headaches, altered mental status, seizures, and sensory deficits. Some patients may be asymptomatic.