Rabies virus encephalitis
ICD-10 A81.1 is a billable code used to indicate a diagnosis of rabies virus encephalitis.
Rabies virus encephalitis is a severe viral infection of the central nervous system (CNS) caused by the rabies virus, a member of the Lyssavirus genus. The disease typically follows an incubation period of 1 to 3 months after exposure, often through bites from infected animals. Initial symptoms may include fever, malaise, and headache, which can progress to neurological manifestations such as confusion, agitation, hallucinations, and paralysis. The hallmark of rabies encephalitis is the rapid progression to severe neurological impairment, including hydrophobia, aerophobia, and ultimately coma and death if not treated promptly. Diagnosis is primarily clinical, supported by history of exposure and laboratory tests, including PCR for rabies virus in saliva or cerebrospinal fluid. Vaccination status is critical; post-exposure prophylaxis (PEP) with rabies vaccine and rabies immune globulin is effective if administered before the onset of symptoms. Once clinical symptoms appear, the prognosis is poor, with a near 100% fatality rate. Understanding the clinical presentation and timely intervention is essential for managing this life-threatening condition.
Thorough documentation of exposure history, vaccination status, and clinical symptoms.
Patients presenting with neurological symptoms after animal bites.
Ensure all relevant lab results and clinical observations are documented to support coding.
Detailed neurological examination findings and progression of symptoms.
Patients with acute neurological decline and suspected viral encephalitis.
Document differential diagnoses and rationale for coding A81.1.
Used when testing for rabies virus in suspected cases.
Document the reason for testing and clinical symptoms.
Infectious disease specialists should ensure thorough documentation of exposure history.
Vaccination status is critical as it influences the management of the patient and the coding process. It helps determine whether post-exposure prophylaxis was administered and impacts the clinical outcome.