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ICD-10 Guide
ICD-10 CodesB05.4

B05.4

Measles with encephalitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B05.4 is a billable code used to indicate a diagnosis of measles with encephalitis.

Key Diagnostic Point:

Measles with encephalitis is a severe complication of measles, a highly contagious viral infection caused by the measles virus. Encephalitis, an inflammation of the brain, can occur in approximately 1 in 1,000 cases of measles. The condition is characterized by symptoms such as high fever, seizures, confusion, and altered consciousness. The pathophysiology involves the immune response to the viral infection, leading to inflammation and potential neurological damage. Diagnosis is typically confirmed through clinical evaluation and serological testing for measles-specific IgM antibodies. Vaccination against measles, primarily through the MMR (measles, mumps, rubella) vaccine, is crucial in preventing this disease and its complications. The incidence of measles has significantly decreased in vaccinated populations, but outbreaks can still occur, particularly in areas with low vaccination rates. Prompt recognition and management of encephalitis are essential to minimize long-term neurological sequelae.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires understanding of both measles and its neurological complications.
  • Differentiation from other viral encephalitides.
  • Need for accurate documentation of encephalitis symptoms.
  • Potential for co-morbid conditions affecting coding.

Audit Risk Factors

  • Inadequate documentation of encephalitis symptoms.
  • Failure to link encephalitis to the measles diagnosis.
  • Misclassification of encephalitis as a separate condition.
  • Lack of vaccination history documentation.

Specialty Focus

Medical Specialties

Pediatrics

Documentation Requirements

Detailed clinical notes on vaccination status, symptoms, and neurological assessments.

Common Clinical Scenarios

Children presenting with fever, rash, and neurological symptoms post-measles infection.

Billing Considerations

Ensure vaccination history is documented to support the diagnosis.

Neurology

Documentation Requirements

Neurological examination findings, imaging results, and treatment plans.

Common Clinical Scenarios

Patients with seizures or altered mental status following measles infection.

Billing Considerations

Document any differential diagnoses considered during evaluation.

Coding Guidelines

Inclusion Criteria

Use B05.4 When
  • Follow ICD
  • CM guidelines for coding infectious diseases and complications
  • Ensure accurate documentation of encephalitis and its relation to measles
  • Include any relevant vaccination history

Exclusion Criteria

Do NOT use B05.4 When
No specific exclusions found.

Related CPT Codes

90460CPT Code

Immunization administration

Clinical Scenario

Administering the MMR vaccine to prevent measles.

Documentation Requirements

Document vaccine type, date administered, and patient consent.

Specialty Considerations

Pediatricians should ensure accurate vaccination records are maintained.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of complications like encephalitis, improving data accuracy and enhancing the ability to track disease outcomes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of complications like encephalitis, improving data accuracy and enhancing the ability to track disease outcomes.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of complications like encephalitis, improving data accuracy and enhancing the ability to track disease outcomes.

Resources

Clinical References

  • •
    CDC Measles Information

Coding & Billing References

  • •
    CDC Measles Information

Frequently Asked Questions

What are the symptoms of measles with encephalitis?

Symptoms include high fever, rash, seizures, confusion, and altered consciousness, typically occurring 7-10 days after the measles rash.