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ICD-10 Guide
ICD-10 CodesB08.010

B08.010

Cowpox

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B08.010 is a billable code used to indicate a diagnosis of cowpox.

Key Diagnostic Point:

Cowpox is a viral infection caused by the cowpox virus, a member of the Orthopoxvirus genus. It primarily affects cattle but can be transmitted to humans, typically through direct contact with infected animals or contaminated materials. The clinical presentation in humans includes localized lesions that resemble those of smallpox, characterized by vesicular and pustular eruptions. The incubation period is usually 7 to 14 days, followed by the appearance of lesions that progress through stages of macules, papules, vesicles, and crusts. While cowpox is generally a self-limiting disease, it can lead to complications such as secondary bacterial infections, particularly in immunocompromised individuals. Vaccination with the smallpox vaccine, which contains a live vaccinia virus, can provide cross-protection against cowpox. However, the use of smallpox vaccination has decreased since the disease was declared eradicated in 1980, leading to a potential resurgence of cowpox cases in unvaccinated populations. Understanding the epidemiology, transmission routes, and clinical management of cowpox is essential for healthcare providers, particularly in veterinary and public health settings.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Limited awareness of cowpox among healthcare providers.
  • Potential for misdiagnosis with other poxvirus infections.
  • Documentation of exposure history may be required.
  • Variability in clinical presentation among patients.

Audit Risk Factors

  • Inadequate documentation of exposure history.
  • Misclassification of cowpox as other poxvirus infections.
  • Failure to document vaccination status.
  • Inconsistent reporting of clinical symptoms.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history including exposure to animals, vaccination status, and clinical symptoms.

Common Clinical Scenarios

Patients presenting with vesicular lesions after contact with infected animals.

Billing Considerations

Consideration of differential diagnoses such as herpes simplex or varicella.

Veterinary Medicine

Documentation Requirements

Records of animal health, vaccination status, and outbreak reports.

Common Clinical Scenarios

Outbreaks in cattle populations and zoonotic transmission cases.

Billing Considerations

Collaboration with public health for tracking and managing outbreaks.

Coding Guidelines

Inclusion Criteria

Use B08.010 When
  • Follow official ICD
  • 10 coding guidelines for viral infections
  • Ensure accurate documentation of the clinical presentation and exposure history

Exclusion Criteria

Do NOT use B08.010 When
  • Exclude other similar conditions before assigning this code

Related CPT Codes

90675CPT Code

Vaccination against smallpox

Clinical Scenario

Administered to individuals at risk of exposure to cowpox.

Documentation Requirements

Record vaccination date, type, and patient response.

Specialty Considerations

Infectious disease specialists should monitor for adverse reactions.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of cowpox, improving data accuracy and facilitating better tracking of viral infections.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of cowpox, improving data accuracy and facilitating better tracking of viral infections.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of cowpox, improving data accuracy and facilitating better tracking of viral infections.

Resources

Clinical References

  • •
    CDC Cowpox Information

Coding & Billing References

  • •
    CDC Cowpox Information

Frequently Asked Questions

What are the common symptoms of cowpox?

Common symptoms include localized vesicular lesions, fever, and malaise, typically appearing 7 to 14 days after exposure.

How is cowpox transmitted?

Cowpox is primarily transmitted through direct contact with infected animals or contaminated materials.

Is there a vaccine for cowpox?

There is no specific vaccine for cowpox; however, smallpox vaccination provides cross-protection.