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v1.0.0
ICD-10 Guide
ICD-10 CodesB16.2

B16.2

Acute hepatitis B with delta-agent infection

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B16.2 is a billable code used to indicate a diagnosis of acute hepatitis b with delta-agent infection.

Key Diagnostic Point:

Acute hepatitis B with delta-agent infection refers to a viral infection of the liver caused by the hepatitis B virus (HBV) in conjunction with the hepatitis D virus (HDV), which can only propagate in the presence of HBV. This condition is characterized by the rapid onset of symptoms such as jaundice, fatigue, abdominal pain, and elevated liver enzymes. The delta agent, or HDV, complicates the clinical picture, often leading to more severe liver disease than HBV infection alone. Transmission occurs primarily through blood and bodily fluids, with high-risk groups including intravenous drug users and individuals with multiple sexual partners. Acute hepatitis B can resolve spontaneously, but the presence of HDV increases the risk of progression to chronic hepatitis and severe liver complications, including cirrhosis and hepatocellular carcinoma. Management typically involves monitoring liver function and, in some cases, antiviral therapy. Understanding the interplay between HBV and HDV is crucial for effective treatment and prevention strategies.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Co-infection with two viruses complicates diagnosis and treatment.
  • Differentiating between acute and chronic hepatitis requires careful evaluation.
  • Documentation must specify the presence of both HBV and HDV.
  • Potential for severe complications necessitates thorough clinical understanding.

Audit Risk Factors

  • Inadequate documentation of co-infection.
  • Failure to specify acute versus chronic status.
  • Misclassification of hepatitis type.
  • Lack of supporting lab results for diagnosis.

Specialty Focus

Medical Specialties

Gastroenterology

Documentation Requirements

Detailed history of liver function tests, serology for HBV and HDV, and imaging studies.

Common Clinical Scenarios

Patients presenting with jaundice, elevated liver enzymes, and a history of high-risk behaviors.

Billing Considerations

Ensure all laboratory results are documented to support the diagnosis of acute hepatitis B with delta-agent.

Infectious Disease

Documentation Requirements

Comprehensive patient history, including risk factors for HBV and HDV, and treatment response.

Common Clinical Scenarios

Patients with acute hepatitis symptoms and a history of exposure to infected individuals.

Billing Considerations

Document any antiviral treatments and patient follow-up plans.

Coding Guidelines

Inclusion Criteria

Use B16.2 When
  • Follow ICD
  • CM guidelines for coding viral hepatitis, ensuring accurate documentation of the acute nature and the presence of delta
  • agent infection
  • Include any relevant laboratory findings and clinical assessments

Exclusion Criteria

Do NOT use B16.2 When
No specific exclusions found.

Related CPT Codes

86803CPT Code

Hepatitis B surface antigen (HBsAg)

Clinical Scenario

Used to confirm the diagnosis of hepatitis B.

Documentation Requirements

Document the reason for testing and results.

Specialty Considerations

Gastroenterology may require additional tests for HDV.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of hepatitis infections, improving the accuracy of data collection and reimbursement processes for acute hepatitis B with delta-agent infection.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of hepatitis infections, improving the accuracy of data collection and reimbursement processes for acute hepatitis B with delta-agent infection.

Reimbursement & Billing Impact

reimbursement processes for acute hepatitis B with delta-agent infection.

Resources

Clinical References

  • •
    CDC Hepatitis B Information

Coding & Billing References

  • •
    CDC Hepatitis B Information

Frequently Asked Questions

What is the significance of delta-agent in hepatitis B?

The delta-agent (HDV) can only infect individuals who are already infected with HBV, leading to more severe liver disease and complications compared to HBV infection alone.