Cytomegaloviral mononucleosis with meningitis
ICD-10 B27.12 is a billable code used to indicate a diagnosis of cytomegaloviral mononucleosis with meningitis.
Cytomegaloviral (CMV) mononucleosis is a viral infection caused by the cytomegalovirus, which is a member of the herpesvirus family. This condition is characterized by symptoms similar to those of infectious mononucleosis, including fever, fatigue, sore throat, and lymphadenopathy. When CMV infection leads to meningitis, it can cause inflammation of the protective membranes covering the brain and spinal cord, resulting in symptoms such as headache, neck stiffness, and altered mental status. Diagnosis typically involves serological tests to detect CMV-specific antibodies, PCR testing for viral DNA, and lumbar puncture to analyze cerebrospinal fluid (CSF) for the presence of the virus. Antiviral treatment options include ganciclovir and foscarnet, which are used primarily in immunocompromised patients, as healthy individuals often recover without specific antiviral therapy. The management of CMV mononucleosis with meningitis requires careful monitoring and supportive care, especially in patients with weakened immune systems.
Detailed history of symptoms, laboratory test results, and treatment plans.
Patients presenting with fever, fatigue, and lymphadenopathy requiring differential diagnosis.
Documentation must clearly indicate the presence of meningitis and the specific viral etiology.
Neurological examination findings, CSF analysis results, and imaging studies.
Patients with altered mental status and neurological symptoms requiring evaluation for viral meningitis.
Accurate documentation of neurological symptoms and their correlation with CMV infection is crucial.
Used when testing for CMV in patients with suspected viral meningitis.
Document the reason for testing and the clinical symptoms leading to the test.
Infectious disease specialists should ensure that the clinical context supports the need for testing.
Common symptoms include fever, fatigue, sore throat, swollen lymph nodes, and in cases with meningitis, headache and neck stiffness.
Diagnosis is made through clinical evaluation, serological tests for CMV antibodies, PCR testing for CMV DNA in CSF, and lumbar puncture.
Antiviral medications such as ganciclovir or foscarnet are used, especially in immunocompromised patients, along with supportive care.
