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v1.0.0
ICD-10 Guide
ICD-10 CodesB33.2

B33.2

Herpesviral Meningitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B33.2 is a billable code used to indicate a diagnosis of herpesviral meningitis.

Key Diagnostic Point:

Herpesviral meningitis is a viral infection of the meninges, the protective membranes covering the brain and spinal cord, primarily caused by the herpes simplex virus (HSV). This condition can manifest as a complication of primary herpes infection or as a reactivation of latent virus. Symptoms typically include fever, headache, neck stiffness, and altered mental status. Diagnosis is often confirmed through lumbar puncture, where cerebrospinal fluid (CSF) analysis reveals pleocytosis, elevated protein levels, and normal glucose levels. PCR testing of the CSF is the gold standard for identifying HSV. Antiviral treatment, primarily with acyclovir, is initiated promptly to reduce morbidity and improve outcomes. Early recognition and treatment are crucial, as herpesviral meningitis can lead to severe neurological complications if left untreated. The condition is more common in immunocompromised patients and can also occur in neonates born to mothers with active genital herpes. Understanding the clinical presentation and diagnostic methods is essential for effective management and coding.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between types of viral meningitis
  • Need for specific laboratory confirmation (PCR testing)
  • Potential for co-infections with other viruses
  • Variability in clinical presentation

Audit Risk Factors

  • Inadequate documentation of symptoms and clinical findings
  • Failure to document laboratory results supporting the diagnosis
  • Misclassification of viral meningitis types
  • Lack of clarity on patient history regarding herpes simplex virus

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, laboratory results, and treatment plans.

Common Clinical Scenarios

Patients presenting with fever, headache, and neck stiffness; patients with known HSV infection.

Billing Considerations

Ensure accurate documentation of HSV status and any prior episodes of meningitis.

Neurology

Documentation Requirements

Neurological examination findings, imaging studies, and CSF analysis results.

Common Clinical Scenarios

Patients with altered mental status and neurological deficits.

Billing Considerations

Document any neurological sequelae and the patient's response to antiviral therapy.

Coding Guidelines

Inclusion Criteria

Use B33.2 When
  • Follow official ICD
  • 10 coding guidelines, ensuring accurate documentation of the diagnosis, laboratory confirmation, and any relevant patient history
  • Include any co
  • existing conditions that may impact treatment

Exclusion Criteria

Do NOT use B33.2 When
No specific exclusions found.

Related CPT Codes

62270CPT Code

Lumbar puncture

Clinical Scenario

Used to obtain CSF for analysis in suspected meningitis cases.

Documentation Requirements

Document indication for procedure, patient consent, and results of CSF analysis.

Specialty Considerations

Neurology specialists should ensure thorough documentation of neurological assessments.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of herpesviral meningitis, improving data accuracy and facilitating better tracking of viral infections.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of herpesviral meningitis, improving data accuracy and facilitating better tracking of viral infections.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of herpesviral meningitis, improving data accuracy and facilitating better tracking of viral infections.

Resources

Clinical References

  • •
    CDC - Viral Meningitis

Coding & Billing References

  • •
    CDC - Viral Meningitis

Frequently Asked Questions

What is the primary cause of herpesviral meningitis?

Herpesviral meningitis is primarily caused by the herpes simplex virus, which can be either type 1 or type 2.

How is herpesviral meningitis diagnosed?

Diagnosis is typically made through lumbar puncture and analysis of cerebrospinal fluid, with PCR testing confirming the presence of HSV.

What are the treatment options for herpesviral meningitis?

The main treatment for herpesviral meningitis is antiviral therapy, primarily with acyclovir, which should be initiated as soon as the diagnosis is suspected.