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v1.0.0
ICD-10 Guide
ICD-10 CodesB38.4

B38.4

Coccidioidomycosis, unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B38.4 is a billable code used to indicate a diagnosis of coccidioidomycosis, unspecified.

Key Diagnostic Point:

Coccidioidomycosis, commonly known as Valley Fever, is a fungal infection caused by the inhalation of spores from the Coccidioides species, primarily C. immitis and C. posadasii. This infection is endemic to certain regions, particularly the southwestern United States, parts of Mexico, and Central and South America. The disease can manifest in various forms, ranging from asymptomatic to severe pulmonary infections, and can disseminate to other parts of the body, including the skin, bones, and central nervous system. Patients may present with flu-like symptoms such as fever, cough, chest pain, and fatigue. In immunocompromised individuals, such as those with HIV/AIDS, cancer, or those on immunosuppressive therapies, the risk of severe disease and dissemination is significantly increased. Diagnosis is typically made through clinical evaluation, serological tests, and imaging studies. Treatment often involves antifungal medications, with fluconazole and itraconazole being the most commonly prescribed. In severe cases, amphotericin B may be indicated. The unspecified designation of this code indicates that the specific manifestation or severity of the disease has not been documented, which can complicate treatment and management.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in clinical presentation and severity of the disease.
  • Need for accurate documentation of symptoms and patient history.
  • Differentiation from other fungal infections.
  • Potential for co-infection in immunocompromised patients.

Audit Risk Factors

  • Inadequate documentation of clinical findings.
  • Failure to specify the severity or site of infection.
  • Misclassification of the infection type.
  • Inconsistent use of antifungal treatment codes.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on symptoms, diagnostic tests, and treatment plans.

Common Clinical Scenarios

Patients presenting with respiratory symptoms, fever, and travel history to endemic areas.

Billing Considerations

Documentation must clearly indicate the immunocompromised status of the patient if applicable.

Pulmonology

Documentation Requirements

Pulmonary function tests, imaging results, and treatment response documentation.

Common Clinical Scenarios

Patients with chronic cough and chest pain who have a history of exposure to Coccidioides.

Billing Considerations

Ensure that any pulmonary complications are well documented to support coding.

Coding Guidelines

Inclusion Criteria

Use B38.4 When
  • According to ICD
  • 10 guidelines, B38
  • 4 should be used when the specific type or severity of coccidioidomycosis is not documented
  • Coders must ensure that the documentation supports the use of this unspecified code and that more specific codes are not applicable

Exclusion Criteria

Do NOT use B38.4 When
No specific exclusions found.

Related CPT Codes

87481CPT Code

Coccidioides antibody test

Clinical Scenario

Used to confirm diagnosis in suspected cases of coccidioidomycosis.

Documentation Requirements

Document the reason for testing and the clinical findings leading to the test.

Specialty Considerations

Infectious disease specialists should ensure comprehensive documentation of the patient's history and exposure.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of fungal infections, including coccidioidomycosis. This specificity aids in better tracking of disease prevalence and treatment outcomes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of fungal infections, including coccidioidomycosis. This specificity aids in better tracking of disease prevalence and treatment outcomes.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of fungal infections, including coccidioidomycosis. This specificity aids in better tracking of disease prevalence and treatment outcomes.

Resources

Clinical References

  • •
    CDC Coccidioidomycosis Information

Coding & Billing References

  • •
    CDC Coccidioidomycosis Information

Frequently Asked Questions

What are the common symptoms of coccidioidomycosis?

Common symptoms include fever, cough, chest pain, fatigue, and in some cases, skin rashes or joint pain. Severe cases may lead to pneumonia or disseminated disease.

How is coccidioidomycosis diagnosed?

Diagnosis is typically made through clinical evaluation, serological tests for antibodies, and imaging studies to assess pulmonary involvement.

What antifungal treatments are used for coccidioidomycosis?

Common antifungal treatments include fluconazole and itraconazole for mild to moderate cases, while amphotericin B may be used for severe cases.