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ICD-10 Guide
ICD-10 CodesB40.81

B40.81

Blastomycotic meningoencephalitis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B40.81 is a billable code used to indicate a diagnosis of blastomycotic meningoencephalitis.

Key Diagnostic Point:

Blastomycotic meningoencephalitis is a severe fungal infection caused by the organism Blastomyces dermatitidis, which primarily affects the lungs but can disseminate to the central nervous system (CNS). This condition is characterized by inflammation of the meninges and brain tissue, leading to symptoms such as fever, headache, neck stiffness, altered mental status, and neurological deficits. The infection is more common in immunocompromised individuals, including those with HIV/AIDS, cancer, or those on immunosuppressive therapy. Diagnosis typically involves a combination of clinical evaluation, imaging studies, and laboratory tests, including cultures and serological tests to identify the presence of the fungus. Treatment usually involves antifungal medications such as itraconazole or amphotericin B, depending on the severity of the infection and the patient's immune status. Early recognition and treatment are crucial to improve outcomes and reduce the risk of complications.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires understanding of fungal infections and their systemic effects.
  • Differentiation from other types of meningoencephalitis.
  • Documentation of immunocompromised status is essential.
  • Potential for co-infections complicating the clinical picture.

Audit Risk Factors

  • Inadequate documentation of the immunocompromised status.
  • Failure to document the specific fungal organism.
  • Lack of supporting lab results for diagnosis.
  • Misclassification of the type of meningoencephalitis.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical history, laboratory results, and treatment plans.

Common Clinical Scenarios

Patients presenting with fever, neurological symptoms, and a history of exposure to endemic areas.

Billing Considerations

Documentation must clearly indicate the diagnosis and any underlying immunocompromising conditions.

Neurology

Documentation Requirements

Neurological examination findings, imaging results, and treatment response.

Common Clinical Scenarios

Patients with altered mental status and neurological deficits requiring differential diagnosis.

Billing Considerations

Ensure that neurological assessments are documented to support the diagnosis of meningoencephalitis.

Coding Guidelines

Inclusion Criteria

Use B40.81 When
  • According to ICD
  • 10 guidelines, B40
  • 81 should be used when the clinical documentation supports a diagnosis of blastomycotic meningoencephalitis
  • It is important to ensure that the documentation includes the specific fungal organism and any relevant immunocompromised status
  • infection is documented

Exclusion Criteria

Do NOT use B40.81 When
  • Exclusion criteria include other types of meningoencephalitis unless co

Related CPT Codes

87481CPT Code

Fungal culture, any source

Clinical Scenario

When a fungal culture is performed to confirm the diagnosis of blastomycosis.

Documentation Requirements

Document the source of the culture and the clinical indication.

Specialty Considerations

Infectious disease specialists should ensure that the culture results are clearly linked to the diagnosis.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of fungal infections, including blastomycosis, which enhances data accuracy and improves patient care through better tracking of disease prevalence and treatment outcomes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of fungal infections, including blastomycosis, which enhances data accuracy and improves patient care through better tracking of disease prevalence and treatment outcomes.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of fungal infections, including blastomycosis, which enhances data accuracy and improves patient care through better tracking of disease prevalence and treatment outcomes.

Resources

Clinical References

  • •
    CDC - Blastomycosis

Coding & Billing References

  • •
    CDC - Blastomycosis

Frequently Asked Questions

What are the common symptoms of blastomycotic meningoencephalitis?

Common symptoms include fever, headache, neck stiffness, altered mental status, and neurological deficits. Patients may also present with respiratory symptoms if there is pulmonary involvement.