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v1.0.0
ICD-10 Guide
ICD-10 CodesB42.81

B42.81

Cerebral sporotrichosis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B42.81 is a billable code used to indicate a diagnosis of cerebral sporotrichosis.

Key Diagnostic Point:

Cerebral sporotrichosis is a rare form of fungal infection caused by the dimorphic fungus Sporothrix schenckii. This organism is typically found in soil, decaying vegetation, and on the skin of infected animals. Cerebral sporotrichosis occurs when the fungus disseminates to the central nervous system, often following a primary cutaneous infection or through direct inoculation. Patients may present with neurological symptoms such as headaches, seizures, altered mental status, and focal neurological deficits. Diagnosis is confirmed through culture of the organism from cerebrospinal fluid (CSF) or brain tissue, as well as serological tests. Treatment typically involves antifungal therapy, with itraconazole being the first-line agent. In severe cases, especially in immunocompromised patients, amphotericin B may be required. The prognosis varies depending on the patient's immune status and the timeliness of treatment initiation. Immunocompromised individuals, such as those with HIV/AIDS or undergoing immunosuppressive therapy, are at a higher risk for disseminated infections, including cerebral sporotrichosis, necessitating vigilant monitoring and prompt intervention.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Rarity of the condition leading to potential unfamiliarity among coders.
  • Need for precise documentation of clinical presentation and treatment.
  • Differentiation from other fungal infections that may present similarly.
  • Potential for misclassification if the underlying immunocompromised state is not documented.

Audit Risk Factors

  • Inadequate documentation of the immunocompromised status.
  • Failure to document the clinical presentation and treatment response.
  • Misdiagnosis or lack of differential diagnosis documentation.
  • Inconsistent coding of related conditions or complications.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on the patient's history, presenting symptoms, and treatment response.

Common Clinical Scenarios

Patients presenting with neurological symptoms and a history of cutaneous sporotrichosis.

Billing Considerations

Ensure thorough documentation of the patient's immune status and any underlying conditions.

Neurology

Documentation Requirements

Neurological examination findings, imaging results, and treatment plans.

Common Clinical Scenarios

Patients with seizures or altered mental status suspected of having cerebral infections.

Billing Considerations

Document any neurological deficits and their progression over time.

Coding Guidelines

Inclusion Criteria

Use B42.81 When
  • Follow the official ICD
  • CM coding guidelines for fungal infections, ensuring accurate documentation of the site of infection and any underlying conditions
  • Include details on the patient's immune status and treatment response

Exclusion Criteria

Do NOT use B42.81 When
No specific exclusions found.

Related CPT Codes

87481CPT Code

Fungal culture, any source

Clinical Scenario

Used when culturing CSF or tissue for diagnosis.

Documentation Requirements

Document the source of the culture and the clinical indication.

Specialty Considerations

Infectious disease specialists should ensure proper specimen handling.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of cerebral sporotrichosis, improving the accuracy of data collection and reimbursement for this rare condition.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of cerebral sporotrichosis, improving the accuracy of data collection and reimbursement for this rare condition.

Reimbursement & Billing Impact

reimbursement for this rare condition.

Resources

Clinical References

  • •
    CDC Fungal Diseases

Coding & Billing References

  • •
    CDC Fungal Diseases

Frequently Asked Questions

What are the common symptoms of cerebral sporotrichosis?

Common symptoms include headaches, seizures, altered mental status, and focal neurological deficits, often following a primary cutaneous infection.