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v1.0.0
ICD-10 Guide
ICD-10 CodesB46.5

B46.5

Candidal endocarditis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B46.5 is a billable code used to indicate a diagnosis of candidal endocarditis.

Key Diagnostic Point:

Candidal endocarditis is a rare but serious fungal infection of the heart valves, primarily caused by Candida species, particularly Candida albicans. This condition typically occurs in immunocompromised patients, such as those with HIV/AIDS, cancer, or those undergoing immunosuppressive therapy. The infection can lead to severe complications, including heart failure, embolic events, and systemic infections. Symptoms may include fever, chills, fatigue, and signs of heart failure. Diagnosis is often confirmed through blood cultures, echocardiography, and clinical evaluation. Treatment usually involves antifungal therapy, with agents such as fluconazole or amphotericin B, and may require surgical intervention for valve replacement in severe cases. Early recognition and management are crucial to improve outcomes in affected patients.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Differentiating candidal endocarditis from bacterial endocarditis
  • Identifying the immunocompromised status of the patient
  • Understanding the nuances of antifungal therapy
  • Documenting the clinical presentation and diagnostic criteria accurately

Audit Risk Factors

  • Inadequate documentation of immunocompromised status
  • Failure to document antifungal treatment plans
  • Lack of clarity in distinguishing between fungal and bacterial infections
  • Insufficient detail in clinical presentation

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed history of immunocompromised conditions, laboratory results, and treatment plans.

Common Clinical Scenarios

Patients with a history of cancer or HIV presenting with fever and heart murmur.

Billing Considerations

Ensure clear documentation of the fungal nature of the infection and any prior antifungal treatments.

Cardiology

Documentation Requirements

Echocardiographic findings, clinical symptoms, and treatment interventions.

Common Clinical Scenarios

Patients with known heart disease presenting with signs of infection.

Billing Considerations

Document the need for surgical intervention if applicable, and the patient's overall cardiac status.

Coding Guidelines

Inclusion Criteria

Use B46.5 When
  • Follow the official ICD
  • CM coding guidelines for infectious diseases, ensuring accurate documentation of the patient's immunocompromised status and the specific fungal infection

Exclusion Criteria

Do NOT use B46.5 When
No specific exclusions found.

Related CPT Codes

93306CPT Code

Echocardiography, transthoracic, real-time with interpretation and report

Clinical Scenario

Used to assess for vegetations in suspected endocarditis cases.

Documentation Requirements

Document the indication for the echocardiogram and findings.

Specialty Considerations

Cardiology specialists should ensure comprehensive reporting of echocardiographic findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of candidal infections, improving the ability to track and manage these cases effectively. It emphasizes the importance of documenting the fungal nature of infections.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of candidal infections, improving the ability to track and manage these cases effectively. It emphasizes the importance of documenting the fungal nature of infections.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of candidal infections, improving the ability to track and manage these cases effectively. It emphasizes the importance of documenting the fungal nature of infections.

Resources

Clinical References

  • •
    CDC - Fungal Diseases

Coding & Billing References

  • •
    CDC - Fungal Diseases

Frequently Asked Questions

What are the common symptoms of candidal endocarditis?

Common symptoms include fever, chills, fatigue, and signs of heart failure such as shortness of breath and edema.

How is candidal endocarditis diagnosed?

Diagnosis is typically made through blood cultures, echocardiography, and clinical evaluation of symptoms.

What antifungal treatments are used for candidal endocarditis?

Common antifungal treatments include fluconazole and amphotericin B, depending on the severity of the infection and the patient's overall health.