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v1.0.0
ICD-10 Guide
ICD-10 CodesB46.8

B46.8

Other specified zygomycoses

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B46.8 is a billable code used to indicate a diagnosis of other specified zygomycoses.

Key Diagnostic Point:

Zygomycosis, also known as mucormycosis, is a rare but serious fungal infection caused by a group of molds called mucormycetes. These fungi are commonly found in soil, decaying organic matter, and even in the nasal mucus of healthy individuals. Zygomycosis primarily affects immunocompromised patients, including those with uncontrolled diabetes, cancer, or those undergoing immunosuppressive therapy. The infection can manifest in various forms, including rhinocerebral, pulmonary, gastrointestinal, and cutaneous zygomycosis. Symptoms may vary depending on the site of infection but often include fever, cough, chest pain, and necrotic lesions. Diagnosis typically involves imaging studies and tissue biopsy. Treatment is aggressive and usually requires antifungal therapy, primarily with amphotericin B, along with surgical debridement of necrotic tissue. Early diagnosis and intervention are crucial for improving outcomes, especially in high-risk populations. The complexity of coding for zygomycosis arises from the need to specify the type of zygomycosis and the underlying conditions of the patient, making accurate documentation essential.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Variety of clinical presentations requiring specific coding
  • Need for detailed patient history and underlying conditions
  • Differentiation from other fungal infections
  • Potential for co-infections complicating the diagnosis

Audit Risk Factors

  • Inadequate documentation of the type of zygomycosis
  • Failure to document the patient's immunocompromised status
  • Misclassification of the infection site
  • Lack of supporting lab results or imaging studies

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on the patient's history, symptoms, and treatment plan.

Common Clinical Scenarios

Patients presenting with fever and respiratory symptoms who are immunocompromised.

Billing Considerations

Ensure all relevant lab results and imaging studies are documented to support the diagnosis.

Oncology

Documentation Requirements

Comprehensive documentation of cancer treatment history and current immunosuppressive therapy.

Common Clinical Scenarios

Cancer patients developing opportunistic infections during chemotherapy.

Billing Considerations

Document the type of cancer and treatment regimen to clarify the patient's risk factors.

Coding Guidelines

Inclusion Criteria

Use B46.8 When
  • Follow the official ICD
  • CM guidelines for coding fungal infections, ensuring to document the specific type of zygomycosis and any underlying conditions
  • Include any relevant laboratory findings and imaging results

Exclusion Criteria

Do NOT use B46.8 When
No specific exclusions found.

Related CPT Codes

87502CPT Code

Fungal culture

Clinical Scenario

Used to confirm the diagnosis of zygomycosis.

Documentation Requirements

Document the reason for the culture and any relevant clinical findings.

Specialty Considerations

Infectious disease specialists should ensure cultures are obtained before starting antifungal therapy.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of zygomycosis, improving the ability to track and manage these infections in clinical practice. It has also enhanced the granularity of data for research and epidemiological studies.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of zygomycosis, improving the ability to track and manage these infections in clinical practice. It has also enhanced the granularity of data for research and epidemiological studies.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of zygomycosis, improving the ability to track and manage these infections in clinical practice. It has also enhanced the granularity of data for research and epidemiological studies.

Resources

Clinical References

  • •
    CDC - Fungal Diseases

Coding & Billing References

  • •
    CDC - Fungal Diseases

Frequently Asked Questions

What are the common symptoms of zygomycosis?

Common symptoms include fever, cough, facial swelling, and necrotic lesions, depending on the site of infection.

How is zygomycosis diagnosed?

Diagnosis typically involves imaging studies, tissue biopsy, and culture of the organism.

What is the primary treatment for zygomycosis?

The primary treatment includes antifungal therapy, particularly with amphotericin B, and surgical debridement of affected tissues.