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ICD-10 Guide
ICD-10 CodesC10.4

C10.4

Billable

Malignant neoplasm of branchial cleft

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C10.4 is a billable code used to indicate a diagnosis of malignant neoplasm of branchial cleft.

Key Diagnostic Point:

C10.4 refers to a malignant neoplasm originating from the branchial cleft, which is a developmental structure in the embryonic phase that can give rise to various types of tumors. These neoplasms are often found in the oropharynx and nasopharynx regions, where they can present with symptoms such as dysphagia, hoarseness, or a palpable mass in the neck. The association of these tumors with human papillomavirus (HPV) is significant, particularly in oropharyngeal cancers, where HPV-positive tumors tend to have a better prognosis compared to HPV-negative ones. Treatment typically involves a multidisciplinary approach, including surgery, radiation therapy, and possibly chemotherapy. Radiation therapy is particularly crucial in managing these tumors, especially when they are locally advanced or when surgical margins are not clear. Accurate coding for C10.4 requires a thorough understanding of the patient's clinical presentation, HPV status, and treatment modalities, as these factors can influence the coding process and subsequent reimbursement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between HPV-positive and HPV-negative tumors
  • Understanding the anatomical location and its implications for treatment
  • Variability in treatment approaches (surgery vs. radiation therapy)
  • Need for precise documentation of clinical findings and treatment plans

Audit Risk Factors

  • Inadequate documentation of HPV status
  • Failure to specify the exact location of the neoplasm
  • Lack of clarity in treatment plans (surgery vs. radiation)
  • Misclassification of tumor type or stage

Specialty Focus

Medical Specialties

Otolaryngology

Documentation Requirements

Detailed clinical notes on tumor location, size, and HPV status; imaging studies; and treatment plans.

Common Clinical Scenarios

Diagnosis of oropharyngeal cancer in patients with a history of HPV; management of neck masses.

Billing Considerations

Ensure accurate staging and documentation of treatment response.

Oncology

Documentation Requirements

Comprehensive treatment plans including chemotherapy and radiation therapy details; follow-up notes.

Common Clinical Scenarios

Management of advanced branchial cleft tumors; coordination of care with radiation oncologists.

Billing Considerations

Documenting the multidisciplinary approach to treatment is essential for accurate coding.

Coding Guidelines

Inclusion Criteria

Use C10.4 When
  • According to the official ICD
  • CM coding guidelines, C10
  • 4 should be used when the documentation clearly indicates a malignant neoplasm of the branchial cleft
  • Coders must ensure that the diagnosis is confirmed by pathology and that any relevant staging information is included

Exclusion Criteria

Do NOT use C10.4 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

21550CPT Code

Excision, tumor, soft tissue of neck or thorax

Clinical Scenario

Used when excising a malignant neoplasm of the branchial cleft.

Documentation Requirements

Operative report detailing the excision and pathology results.

Specialty Considerations

Otolaryngology specialists must ensure clear documentation of tumor margins.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of malignant neoplasms, including those of the branchial cleft, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of malignant neoplasms, including those of the branchial cleft, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What is the significance of HPV status in coding C10.4?

HPV status is crucial as it can influence treatment decisions and prognosis. Accurate documentation of HPV status is necessary for proper coding and may affect reimbursement.