ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesC18.3

C18.3

Billable

Malignant neoplasm of hepatic flexure

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C18.3 is a billable code used to indicate a diagnosis of malignant neoplasm of hepatic flexure.

Key Diagnostic Point:

C18.3 refers to a malignant neoplasm located at the hepatic flexure of the colon, which is the bend between the ascending colon and the transverse colon. This area is significant in colorectal cancer (CRC) as it can be a site for tumor development due to various risk factors including age, family history, and lifestyle choices. Colorectal cancer is characterized by the uncontrolled growth of abnormal cells in the colon or rectum, often presenting with symptoms such as changes in bowel habits, rectal bleeding, and abdominal discomfort. Screening for colorectal cancer typically begins at age 45, with methods including colonoscopy, fecal occult blood tests, and imaging studies. Staging of the cancer is crucial for determining treatment options and prognosis, with the TNM system being the most widely used. Additionally, microsatellite instability (MSI) testing can provide insights into the tumor's genetic characteristics, influencing treatment decisions. Surgical approaches may include resection of the affected segment of the colon, often accompanied by chemotherapy or radiation therapy depending on the stage of the disease.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Specificity of the location within the colon
  • Need for accurate staging information
  • Variability in treatment approaches based on tumor characteristics
  • Documentation of screening and diagnostic procedures

Audit Risk Factors

  • Inadequate documentation of tumor location
  • Failure to document staging information
  • Misclassification of the neoplasm type
  • Lack of supporting documentation for screening procedures

Specialty Focus

Medical Specialties

Oncology

Documentation Requirements

Detailed pathology reports, imaging studies, and treatment plans.

Common Clinical Scenarios

Diagnosis and treatment planning for colorectal cancer, follow-up care post-surgery.

Billing Considerations

Ensure accurate staging and documentation of treatment response.

Gastroenterology

Documentation Requirements

Endoscopy reports, biopsy results, and screening recommendations.

Common Clinical Scenarios

Screening for colorectal cancer, management of polyps, and follow-up after diagnosis.

Billing Considerations

Document the rationale for screening and any findings during procedures.

Coding Guidelines

Inclusion Criteria

Use C18.3 When
  • According to ICD
  • CM guidelines, C18
  • 3 should be used when the documentation specifies a malignant neoplasm at the hepatic flexure
  • Coders must ensure that the diagnosis is confirmed by pathology and that staging is documented when applicable

Exclusion Criteria

Do NOT use C18.3 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

45378CPT Code

Colonoscopy, flexible, diagnostic

Clinical Scenario

Used for screening or diagnosis of colorectal cancer.

Documentation Requirements

Indication for procedure, findings, and any biopsies taken.

Specialty Considerations

Gastroenterologists should document findings thoroughly to support coding.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of colorectal cancers, improving the accuracy of data collection and reimbursement processes. C18.3 provides a clear designation for tumors located at the hepatic flexure, which was less specific in ICD-9.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of colorectal cancers, improving the accuracy of data collection and reimbursement processes. C18.3 provides a clear designation for tumors located at the hepatic flexure, which was less specific in ICD-9.

Reimbursement & Billing Impact

reimbursement processes. C18.3 provides a clear designation for tumors located at the hepatic flexure, which was less specific in ICD-9.

Resources

Clinical References

  • •
    American Cancer Society - Colorectal Cancer

Coding & Billing References

  • •
    American Cancer Society - Colorectal Cancer

Frequently Asked Questions

What is the significance of microsatellite instability in colorectal cancer?

Microsatellite instability (MSI) is a condition of genetic hypermutability that can indicate a higher risk for certain types of colorectal cancer, particularly in patients with Lynch syndrome. Testing for MSI can help guide treatment decisions, including the use of immunotherapy.