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v1.0.0
ICD-10 Guide
ICD-10 CodesC22.2

C22.2

Billable

Hepatoblastoma

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C22.2 is a billable code used to indicate a diagnosis of hepatoblastoma.

Key Diagnostic Point:

Hepatoblastoma is a rare malignant tumor of the liver that primarily affects children, typically under the age of 3. It arises from immature liver cells and is characterized by a variety of histological patterns. The tumor can present as a solitary mass or multiple nodules within the liver. Symptoms may include abdominal swelling, pain, jaundice, and elevated alpha-fetoprotein (AFP) levels, which are often used as a tumor marker for diagnosis and monitoring treatment response. Hepatoblastoma is associated with certain genetic syndromes, such as Beckwith-Wiedemann syndrome and familial adenomatous polyposis. Treatment usually involves a combination of surgical resection and chemotherapy, with liver transplantation being considered in cases of unresectable tumors or those with significant liver dysfunction. The prognosis for hepatoblastoma is generally favorable, especially when diagnosed early and treated appropriately.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in presentation and staging of the tumor
  • Need for accurate documentation of AFP levels
  • Differentiation from other liver tumors, such as hepatocellular carcinoma
  • Consideration of associated conditions like cirrhosis

Audit Risk Factors

  • Inadequate documentation of tumor staging
  • Failure to document AFP levels
  • Misclassification of tumor type
  • Lack of clarity on treatment modalities used

Specialty Focus

Medical Specialties

Pediatric Oncology

Documentation Requirements

Detailed clinical notes on tumor characteristics, treatment plans, and response to therapy.

Common Clinical Scenarios

Diagnosis and management of hepatoblastoma, monitoring AFP levels, and planning for potential liver transplantation.

Billing Considerations

Ensure accurate staging and documentation of associated genetic syndromes.

Pediatric Surgery

Documentation Requirements

Operative reports detailing surgical interventions, including resection and transplantation.

Common Clinical Scenarios

Surgical management of hepatoblastoma, including indications for liver transplantation.

Billing Considerations

Document the rationale for surgical decisions and any complications encountered.

Coding Guidelines

Inclusion Criteria

Use C22.2 When
  • Follow official ICD
  • CM coding guidelines for neoplasms, ensuring accurate documentation of tumor type, stage, and associated conditions
  • Include any relevant laboratory results, such as AFP levels, in the medical record

Exclusion Criteria

Do NOT use C22.2 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

47120CPT Code

Liver resection

Clinical Scenario

Used in cases where the hepatoblastoma is resectable.

Documentation Requirements

Operative report detailing the extent of resection and any complications.

Specialty Considerations

Pediatric surgical documentation must include indications for surgery and post-operative care.

47133CPT Code

Liver transplantation

Clinical Scenario

Indicated for unresectable hepatoblastoma.

Documentation Requirements

Comprehensive documentation of the transplant procedure and post-operative management.

Specialty Considerations

Ensure coordination between oncology and transplant teams.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of hepatoblastoma, improving the accuracy of data collection and reimbursement processes. It has also facilitated better tracking of treatment outcomes and epidemiological studies.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of hepatoblastoma, improving the accuracy of data collection and reimbursement processes. It has also facilitated better tracking of treatment outcomes and epidemiological studies.

Reimbursement & Billing Impact

reimbursement processes. It has also facilitated better tracking of treatment outcomes and epidemiological studies.

Resources

Clinical References

  • •
    National Cancer Institute - Hepatoblastoma

Coding & Billing References

  • •
    National Cancer Institute - Hepatoblastoma

Frequently Asked Questions

What is the typical age of onset for hepatoblastoma?

Hepatoblastoma typically occurs in children under the age of 3, with the majority of cases diagnosed in infants and toddlers.

How is hepatoblastoma diagnosed?

Diagnosis is made through imaging studies, elevated AFP levels, and histological examination of liver tissue.

What are the treatment options for hepatoblastoma?

Treatment options include surgical resection, chemotherapy, and in some cases, liver transplantation.