ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesC46.0

C46.0

Billable

Kaposi's sarcoma of skin

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C46.0 is a billable code used to indicate a diagnosis of kaposi's sarcoma of skin.

Key Diagnostic Point:

Kaposi's sarcoma (KS) is a type of cancer that manifests as lesions on the skin and is characterized by the proliferation of blood vessels and connective tissue. It is most commonly associated with immunocompromised states, particularly in patients with HIV/AIDS. The lesions can appear as red, purple, or brown spots on the skin and may also affect mucosal surfaces and internal organs. KS is caused by the human herpesvirus 8 (HHV-8), which is often found in individuals with weakened immune systems. The condition can be classified into different types, including classic, endemic, epidemic (associated with HIV), and iatrogenic. The epidemic form is particularly aggressive and can lead to significant morbidity if not treated promptly. Treatment options vary based on the extent of the disease and may include antiretroviral therapy for HIV-positive patients, chemotherapy, radiation therapy, and local treatments such as cryotherapy or laser therapy. Early diagnosis and intervention are crucial for improving outcomes in patients with Kaposi's sarcoma.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Association with HIV/AIDS complicates coding due to the need for additional codes.
  • Variety of treatment options may require documentation of specific interventions.
  • Differentiation from other skin lesions can be challenging.
  • Potential for multiple site involvement necessitates careful coding.

Audit Risk Factors

  • Inadequate documentation of HIV status.
  • Failure to document the extent of lesions.
  • Misclassification of KS as another skin condition.
  • Lack of clarity on treatment modalities used.

Specialty Focus

Medical Specialties

Oncology

Documentation Requirements

Detailed pathology reports and treatment plans must be documented.

Common Clinical Scenarios

Patients presenting with skin lesions and a known history of HIV.

Billing Considerations

Ensure that the relationship between KS and HIV is clearly documented.

Infectious Disease

Documentation Requirements

Documentation of viral load and CD4 counts is essential.

Common Clinical Scenarios

Patients with advanced HIV presenting with skin lesions.

Billing Considerations

Linkage between HIV management and KS treatment must be clear.

Coding Guidelines

Inclusion Criteria

Use C46.0 When
  • Follow ICD
  • CM guidelines for coding neoplasms, ensuring that the primary diagnosis reflects the site and type of cancer
  • Include additional codes for HIV status and any related complications

Exclusion Criteria

Do NOT use C46.0 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used for patients receiving chemotherapy for KS.

Documentation Requirements

Document the specific chemotherapy agent and dosage.

Specialty Considerations

Oncology specialists must ensure accurate coding of treatment regimens.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of Kaposi's sarcoma, improving the ability to capture the nuances of the disease and its association with HIV, which is crucial for appropriate treatment and reimbursement.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of Kaposi's sarcoma, improving the ability to capture the nuances of the disease and its association with HIV, which is crucial for appropriate treatment and reimbursement.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    Kaposi's Sarcoma Foundation

Coding & Billing References

  • •
    Kaposi's Sarcoma Foundation

Frequently Asked Questions

What is the significance of coding C46.0 in relation to HIV?

Coding C46.0 accurately reflects the association between Kaposi's sarcoma and HIV, which is critical for treatment planning and understanding the patient's overall health status.