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v1.0.0
ICD-10 Guide
ICD-10 CodesChapter 2: NeoplasmsC53

C53

Billable

Malignant neoplasm of cervix uteri

Chapter 2:Neoplasms

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C53 is a billable code used to indicate a diagnosis of malignant neoplasm of cervix uteri.

Key Diagnostic Point:

C53 refers to malignant neoplasms of the cervix uteri, which are cancers that arise from the cervical tissue. The cervix is the lower part of the uterus that connects to the vagina. The most common type of cervical cancer is squamous cell carcinoma, followed by adenocarcinoma. Risk factors include persistent infection with high-risk human papillomavirus (HPV), smoking, and immunosuppression. Symptoms may include abnormal vaginal bleeding, pelvic pain, and unusual discharge. Diagnosis typically involves a Pap smear, HPV testing, and biopsy. Staging of cervical cancer is crucial for determining treatment options and prognosis, classified from Stage 0 (carcinoma in situ) to Stage IV (advanced disease). CA-125 is a tumor marker that may be elevated in some cases, but it is not specific for cervical cancer. Treatment options include surgery (such as hysterectomy), radiation therapy, and chemotherapy, depending on the stage and overall health of the patient.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of staging classifications (FIGO staging)
  • Differentiation between types of cervical cancer
  • Need for accurate documentation of symptoms and diagnostic tests
  • Potential for co-existing conditions affecting treatment

Audit Risk Factors

  • Inadequate documentation of staging
  • Failure to specify type of cervical cancer
  • Misreporting of treatment modalities
  • Inconsistent use of CA-125 levels in documentation

Specialty Focus

Medical Specialties

Gynecologic Oncology

Documentation Requirements

Detailed pathology reports, staging information, treatment plans, and follow-up care notes.

Common Clinical Scenarios

Diagnosis and management of cervical cancer, including pre-operative assessments and post-operative care.

Billing Considerations

Ensure accurate coding of the specific type of cervical cancer and any associated procedures.

Radiation Oncology

Documentation Requirements

Radiation treatment plans, dosimetry calculations, and patient response assessments.

Common Clinical Scenarios

Administration of radiation therapy for cervical cancer treatment.

Billing Considerations

Documentation must clearly link the diagnosis to the treatment provided.

Coding Guidelines

Inclusion Criteria

Use C53 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the diagnosis, staging, and treatment
  • Include any relevant history and co
  • morbidities that may affect the coding

Exclusion Criteria

Do NOT use C53 When
No specific exclusions found.

Related CPT Codes

58150CPT Code

Total abdominal hysterectomy

Clinical Scenario

Performed for treatment of cervical cancer.

Documentation Requirements

Operative report detailing the procedure and findings.

Specialty Considerations

Gynecologic oncology specialists must ensure accurate coding of the procedure.

88305CPT Code

Pathology examination of cervical biopsy

Clinical Scenario

Used to confirm diagnosis of cervical cancer.

Documentation Requirements

Pathology report must be linked to the diagnosis.

Specialty Considerations

Ensure that the pathology report is complete and accurate.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of cervical cancer, improving the accuracy of data collection and treatment tracking. It has also enhanced the ability to capture the complexity of staging and treatment options.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of cervical cancer, improving the accuracy of data collection and treatment tracking. It has also enhanced the ability to capture the complexity of staging and treatment options.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of cervical cancer, improving the accuracy of data collection and treatment tracking. It has also enhanced the ability to capture the complexity of staging and treatment options.

Resources

Clinical References

  • •
    American Cancer Society - Cervical Cancer
  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Coding & Billing References

  • •
    American Cancer Society - Cervical Cancer
  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Frequently Asked Questions

What are the common symptoms of cervical cancer?

Common symptoms include abnormal vaginal bleeding, pelvic pain, and unusual discharge. Early-stage cervical cancer may not present any symptoms.

How is cervical cancer staged?

Cervical cancer is staged using the FIGO system, which classifies the cancer from Stage 0 (carcinoma in situ) to Stage IV (advanced disease).