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v1.0.0
ICD-10 Guide
ICD-10 CodesC82.19

C82.19

Billable

Follicular lymphoma grade II, extranodal and solid organ sites

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.19 is a billable code used to indicate a diagnosis of follicular lymphoma grade ii, extranodal and solid organ sites.

Key Diagnostic Point:

Follicular lymphoma grade II is a type of non-Hodgkin lymphoma characterized by the proliferation of follicle center (germinal center) B-cells. This subtype is classified as grade II due to its intermediate histological features, which indicate a higher proliferation rate than grade I but lower than grade III. Extranodal involvement refers to the presence of lymphoma outside of lymph nodes, affecting solid organ sites such as the spleen, liver, or bone marrow. Patients may present with B-symptoms, which include fever, night sweats, and unexplained weight loss. Diagnosis typically involves imaging studies, biopsy, and immunophenotyping to confirm the presence of CD10, CD19, and BCL2 markers. Treatment protocols often include chemotherapy regimens such as R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone) or targeted therapies, depending on the stage and patient factors. The prognosis varies based on the extent of disease and response to initial therapy.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation between grades of follicular lymphoma
  • Identification of extranodal involvement
  • Need for precise staging information
  • Documentation of B-symptoms

Audit Risk Factors

  • Inadequate documentation of B-symptoms
  • Failure to specify extranodal involvement
  • Incorrect staging information
  • Misclassification of lymphoma grade

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Comprehensive clinical notes, pathology reports, imaging studies, and treatment plans.

Common Clinical Scenarios

Diagnosis and management of patients with newly diagnosed follicular lymphoma, monitoring treatment response, and managing relapsed disease.

Billing Considerations

Ensure accurate documentation of staging and treatment response to support coding and billing.

Pathology

Documentation Requirements

Detailed histopathology reports, immunohistochemistry results, and grading information.

Common Clinical Scenarios

Biopsy interpretation for suspected lymphoma cases and grading of lymphoma specimens.

Billing Considerations

Accurate reporting of immunophenotyping results is crucial for correct coding.

Coding Guidelines

Inclusion Criteria

Use C82.19 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the lymphoma grade, extranodal involvement, and any associated symptoms
  • Include staging information as per the Ann Arbor classification

Exclusion Criteria

Do NOT use C82.19 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used for administering chemotherapy to patients with follicular lymphoma.

Documentation Requirements

Document the specific chemotherapy regimen and patient response.

Specialty Considerations

Oncology specialists must ensure accurate coding of chemotherapy administration.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and reimbursement processes. It has also facilitated better tracking of treatment outcomes and disease progression.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and reimbursement processes. It has also facilitated better tracking of treatment outcomes and disease progression.

Reimbursement & Billing Impact

reimbursement processes. It has also facilitated better tracking of treatment outcomes and disease progression.

Resources

Clinical References

  • •
    American Cancer Society - Lymphoma

Coding & Billing References

  • •
    American Cancer Society - Lymphoma

Frequently Asked Questions

What are the common symptoms of follicular lymphoma?

Common symptoms include painless swelling of lymph nodes, fever, night sweats, weight loss, and fatigue. Some patients may also experience abdominal discomfort if there is splenic or liver involvement.