Follicular lymphoma grade III, unspecified, spleen
ICD-10 C82.27 is a billable code used to indicate a diagnosis of follicular lymphoma grade iii, unspecified, spleen.
Follicular lymphoma is a type of non-Hodgkin lymphoma characterized by the proliferation of follicle center (germinal center) B-cells. Grade III follicular lymphoma indicates a more aggressive form of the disease, with a higher proliferation index and a tendency to transform into a more aggressive lymphoma. When classified as 'unspecified,' it indicates that the specific characteristics of the lymphoma have not been detailed. In cases where the spleen is involved, patients may present with splenomegaly, which can lead to symptoms such as abdominal discomfort or fullness. The disease may also manifest with B-symptoms, including fever, night sweats, and weight loss, which are indicative of systemic involvement. Treatment protocols often include chemotherapy regimens, immunotherapy, or targeted therapies, depending on the stage of the disease and the patient's overall health. Regular monitoring and staging through imaging studies are crucial for assessing disease progression and treatment efficacy.
Detailed clinical notes on patient history, physical examination findings, and treatment plans.
Diagnosis of follicular lymphoma, treatment initiation, and follow-up assessments.
Ensure accurate staging and grading are documented to support coding.
Histopathological reports detailing the grade and subtype of lymphoma.
Biopsy evaluations and interpretation of lymph node or spleen samples.
Pathology reports must clearly indicate the grade and any transformation of the lymphoma.
Used to monitor blood counts during treatment for lymphoma.
Document the reason for the CBC and any findings.
Hematology/Oncology specialists should ensure CBC results are correlated with clinical findings.
Common treatments include chemotherapy regimens such as R-CHOP, immunotherapy with monoclonal antibodies, and targeted therapies. Treatment plans are individualized based on the patient's overall health and disease stage.
